Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

Saikosaponin D, a natural product isolated and purified from the herb of Bupleurum chinense DC., is a SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity and a potent inhibitor on acute hepatic injury by CCl4 and a potent cytotoxicity agent for human hepatocellular carcinoma cells, and has the antiproliferative effect in A549 cells that may be the induction of p53 and activity of the Fas/FasL apoptotic system.

Ginsenoside Re is a panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.

Acetylcysteine is an inhibitor of ROS and the production of TNF. It is a pharmaceutical drug and nutritional supplement used as mucolytic agent.

L-Glutamine is an essential amino acid which serves as a substrate for biosynthesis of neurotransmitters glutamate and GABA in neurons.

Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP.

Y-27632 dihydrochloride 是一种 ATP 竞争性的 ROCK 抑制剂，具有口服活性。Y-27632 dihydrochloride 具有一定的抗癫痫作用.

SB 431542 是一种用于 SMAD 信号传导的 TGF-β 受体激酶抑制剂 (TRKI)。

Retinoic acid (Vitamin A acid)作为 RAR 核受体的激动剂，用于细胞疗法中的辅助试剂。

IWR-1是一种抑制Wnt/β-连环蛋白信号通路的tankyrase抑制剂。

Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase. It is commonly used to raise levels of cAMP in the research of cell physiology.

Laduviglusib (CHIR-99021)是一种有效、选择性且具有口服活性的 GSK-3α/β 抑制剂，可用作细胞疗法中的辅助试剂。

DAPT (GSI-IX)是一种强效且具有口服活性的 γ-secretase 抑制剂，可用于细胞疗法中的辅助试剂。

A 83-01（GMP）是一种GMP级别的A 83-01。 GMP级别的小分子可以用作细胞治疗的辅助试剂。 A 83-01是一种有效的ALK4/5/7抑制剂。

Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.