Infigratinib（BGJ-398；NVP-BGJ398）对FGFR家族具有强效抑制作用，对FGFR1、FGFR2、FGFR3和FGFR4的IC50值分别为0.9 nM、1.4 nM、1 nM和60 nM。

Nintedanib（BIBF 1120）是一种强效的三重血管激酶抑制剂，对VEGFR1/2/3、FGFR1/2/3和PDGFRα/β的IC50值分别为34 nM、13 nM、13 nM、69 nM、37 nM、108 nM、59 nM和65 nM。

Pemigatinib, also known as INCB054828, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. FGFR inhibitor INCB054828 binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells.

ODM-203 is a selective inhibitor of FGFR and VEGFR with IC50 values of 11, 16, 6, 35nM for recombinant FGFR1-4 and 26, 9, 5nM for VEGFR1-3, respectively.

FGFR-IN-1 is a potent and highly selective FGFR inhibitor, used for antitumor treatment.

ASP5878 是一种口服活性的 FGFR 1、2、3 和 4 的抑制剂，IC50 值分别为 0.47 nM、0.6 nM、0.74 nM 和 3.5 nM，具有潜在的抗肿瘤活性。

Derazantinib is a fibroblast growth factor receptor (FGFR) inhibitor that has antitumor activity.

H3B-6527 是一种口服活性、高选择性且共价的 FGFR4 抑制剂，IC50 小于 1.2 nM。它对 FGFR1-3 的 IC50 值分别为 320、1290 和 1060 nM。H3B-6527 表现出强大的抗癌活性。

FGF401, an inhibitor of human fibroblast growth factor receptor 4 (FGFR4, IC50 = 1.1 nM), has potential antineoplastic activity.

PRN1371 is an irreversible covalent FGFR inhibitor used for the treatment of solid tumor.

BLU-554 is a selective inhibitor of FGFR4 with the IC50 of 5 nM.

BLU9931 is an inhibitor of FGFR4 with IC50 of 3 nM and is less potent for FGFR1/2/3 (IC50 > 150 nM).

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.

CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM.

FIIN-3 is an irreversible inhibitor of FGFR1-4 with IC50s of 13, 21, 31, and 35 nM, respectively.