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氧卡地平 /Oxysophocarpine {[allProObj[0].p_purity_real_show]}

货号:A633566 同义名: 氧化槐果碱 / Sophocarpine N-oxide;OSC

Oxysophocarpine, a natural product isolated and purified from the root of Styphnolobium japonicum (L.) Schott., can decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, and may be a drug for colonic inflammation and NASH.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Oxysophocarpine 化学结构 CAS号:26904-64-3
Oxysophocarpine 化学结构
CAS号:26904-64-3
Oxysophocarpine 3D分子结构
CAS号:26904-64-3
Oxysophocarpine 化学结构 CAS号:26904-64-3
Oxysophocarpine 3D分子结构 CAS号:26904-64-3
规格 价格 会员价 库存 数量
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Oxysophocarpine 纯度/质量文件 产品仅供科研

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Oxysophocarpine 生物活性

描述 Oxysophocarpine, a natural product isolated and purified from the root of Styphnolobium japonicum (L.) Schott., can decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, and may be a drug for colonic inflammation and NASH.

Oxysophocarpine 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02239237 - Completed - China, Hebei ... 展开 >> HanDan Central Hospital HanDan, Hebei, China, 056001 Handan First Hospital Handan, Hebei, China, 056002 Bai Qiu'en International Peace Hospital Shijiazhuang, Hebei, China, 050082 China, Henan Henan University Huaihe Hospital Kaifeng, Henan, China, 475001 The First Affiliated Hospital of Henan University of Science & Technology Luoyang, Henan, China, 471000 Luoyang Central Hospital Affiliated to Zhengzhou University Luoyang, Henan, China, 471009 Xinxiang Central Hospital Xinxiang, Henan, China, 453000 The First Affiliated Hospital of Xinxiang Medical University Xinxiang, Henan, China, 453199 Xinyang Central Hospital Xinyang, Henan, China, 464000 People's Hospital of Zhengzhou Zhengzhou, Henan, China, 450003 Henan Cancer Hospital Zhengzhou, Henan, China, 450008 The First Hospital of Henan College of Traditional Chinese Medicine Zhengzhou, Henan, China, 451199 China, Shandong Shandong Provincial Western Hospital Jinan, Shandong, China, 250022 Qingdao Center Hospital Qingdao, Shandong, China, 266031 Tai'an Central Hospital Tai'an, Shandong, China, 271000 The 88th Hospital of People's Liberation Army Tai'an, Shandong, China, 271002 People's Hospital of Xintai City Tai'an, Shandong, China, 271200 Weifang No.2 People's Hospital Weifang, Shandong, China, 261041 Weihai Municipal Hospital Weihai, Shandong, China, 264299 Central Hospital of Zibo Zibo, Shandong, China, 255020 China, Shanxi Jincheng General Hospital Jincheng, Shanxi, China, 048006 The Fourth People's Hospital of Linfen Linfen, Shanxi, China, 041099 Traditional Chinese Hospital of Shanxi Taiyuan, Shanxi, China, 030012 Yuncheng Central Hospital Yuncheng, Shanxi, China, 044099 China, Sichuan Chengdu Second People's Hospital Chengdu, Sichuan, China, 610017 AVIC 363 Hospital Chengdu, Sichuan, China, 610041 Teaching Hospital of Chengdu University of T.C.M. Chengdu, Sichuan, China, 610072 The Second People's Hospital of Yibin Yibin, Sichuan, China, 644000 China, Tianjin Tianjin medical university cancer institute & hosptial Tianjin, Tianjin, China, 300060 收起 <<

Oxysophocarpine 参考文献

[1]Wu L, Zhong W, et al. Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and its intestinal absorption and metabolism in rat. Fitoterapia. 2015 Sep;105:26-36.

[2]Yang Y, Li YX, et al. Oxysophocarpine Ameliorates Carrageenan-induced Inflammatory Pain via Inhibiting Expressions of Prostaglandin E2 and Cytokines in Mice. Planta Med. 2015 Jul;81(10):791-7.

Oxysophocarpine 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.81mL

0.76mL

0.38mL

19.06mL

3.81mL

1.91mL

38.12mL

7.62mL

3.81mL

Oxysophocarpine 技术信息

CAS号26904-64-3
分子式C15H22N2O2
分子量 262.347
别名 氧化槐果碱 ;Sophocarpine N-oxide;OSC;Oxysophocarpine, Sophocarpine N-oxide;(+)-Oxysophocarpine
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,2-8°C

溶解度

DMSO: 35 mg/mL(133.41 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 50 mg/mL(190.59 mM),配合低频超声助溶

动物实验配方
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