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全部(71) Modulator(1) Agonist(1) Inhibitor(2) Activator(7)
1alpha-Hydroxy VD4 , a 1alpha (OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
Falecalcitriol is an analog of calcitriol with a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.
Calcifediol-d3 是 Calcifediol 的氘代物。Calcifediol 是维生素 D3 的主要循环代谢物,并且是一种有效的 VDR 配体。
MeTC7是一种维生素 D 受体 (VDR) 拮抗剂,IC50 值为 2.9 μM,显示出良好的抗肿瘤活性。
Calcipotriol monohydrate是维生素D3的合成类似物,对维生素D受体具有高亲和力。
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
Vitamin D4 is the active analogue of Vitamin D.
Alfacalcidol is a non-selective VDR activator medication.
Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
Paricalcitol是一种维生素D类似物,作为维生素D受体激动剂,用于预防和治疗与慢性肾衰竭相关的继发性甲状旁腺功能亢进症。
Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
Eldecalcitol, an analog of vitamin D, is a drug used for the treatment of osteoporosis.
Calcifediol is an active metabolite of vitamin D. It can inhibit the secretion of parathyroid hormone with 2 nM and commonly used as an indicator of body vitamin D status.
Calcitriol 是维生素 D3 的活性形式,对维生素 D 受体(VDR)具有高亲和力,IC50 值为 1 nM。Calcitriol 具有调节钙磷代谢、抗炎和抗肿瘤作用,可用于骨质疏松症、慢性肾病和癌症的研究。
Calcitriol Impurities A is an impurity of calcitriol, and calcitriol is the hormonally active form of vitamin D, an active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
Tacalcitol promotes normal bone development by regulating calcium.
Vitamin D3 是一种脂溶性维生素,具有调节钙和磷代谢的作用。Vitamin D3 主要用于骨骼健康、免疫功能和癌症预防的研究。
Calcifediol-d6是氘代的Calcifediol,其为维生素D3在肝脏经羟基化后的前激素,是一种有效的VDR抑制剂。
Tags: VD/VDR | 维生素D相关/核受体 | Vitamin D related/nuclear receptor | 代谢酶 | Metabolic Enzyme | VD/VDR 相关产品
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