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帕立骨化醇 /Paricalcitol {[allProObj[0].p_purity_real_show]}

货号:A494988 同义名: 1α,25-Dihydroxy-19-nor-vitamin D2;Zemplar

Paricalcitol是一种维生素D类似物,作为维生素D受体激动剂,用于预防和治疗与慢性肾衰竭相关的继发性甲状旁腺功能亢进症。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Paricalcitol 化学结构 CAS号:131918-61-1
Paricalcitol 化学结构
CAS号:131918-61-1
Paricalcitol 3D分子结构
CAS号:131918-61-1
Paricalcitol 化学结构 CAS号:131918-61-1
Paricalcitol 3D分子结构 CAS号:131918-61-1
规格 价格 会员价 库存 数量
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Paricalcitol 纯度/质量文件 产品仅供科研

货号:A494988 标准纯度: {[allProObj[0].p_purity_real_show]}
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Paricalcitol 生物活性

描述 Paricalcitol is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.

Paricalcitol 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01204528 Chronic Kidney Disease Phase 2 Phase 3 Completed - Sweden ... 展开 >> Karolinska Institute at Danderyd University Hospital Danderyd, Stockholm, Sweden, 18288 收起 <<
NCT02018133 CKD Stage 3/4 Phase 3 Completed - United States, Illinois ... 展开 >> University of Illinois at Chicago Chicago, Illinois, United States, 60612 收起 <<
NCT03138720 Resectable Pancreatic Cancer ... 展开 >> Unresectable Pancreatic Cancer Pancreatic Adenocarcinoma 收起 << Phase 2 Recruiting March 1, 2020 United States, Arizona ... 展开 >> HonorHealth Research Institute Recruiting Scottsdale, Arizona, United States, 85258 Contact: Joyce Schaffer, MSN, AOCNS    480-323-1339 ext option #2    Joyce.Schaffer@HonorHealth.com    Principal Investigator: Erkut Borazanci, MD 收起 <<

Paricalcitol 参考文献

[1]Suarez-Martinez E, Husain K, et al. Adiponectin expression and the cardioprotective role of the vitamin D receptor activator paricalcitol and the angiotensin converting enzyme inhibitor enalapril in ApoE-deficient mice. Ther Adv Cardiovasc Dis. 2014 Dec;8(6):224-36.

[2]Halder SK, Sharan C, et al. Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids. Reprod Sci. 2014 Sep;21(9):1108-19.

Paricalcitol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

12.00mL

2.40mL

1.20mL

24.00mL

4.80mL

2.40mL

Paricalcitol 技术信息

CAS号131918-61-1
分子式C27H44O3
分子量 416.637
别名 1α,25-Dihydroxy-19-nor-vitamin D2;Zemplar;paricalcitol-d6;Abbott brand of paricalcitol;Paracalcin;19-Nor-1alpha,25-dihydroxyvitamin D2;Compound 49510;19-nor-1,25-Dihydroxyvitamin D2
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Store in freezer, under -20°C

溶解度

DMSO: 105 mg/mL(252.02 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 12.5 mg/mL(30 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

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