| Penfluridol |
+
Dopamine receptor, Ki: 1.6 μM
|
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Ansofaxine HCl |
++
Dopamine receptor, IC50: 491 nM
|
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Tetrahydroberberine,THB |
|
+
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Prochlorperazine Maleate |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Olanzapine |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Trifluoperazine |
|
++++
Dopamine D2 receptor, IC50: 1.1 nM
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Ropinirole hydrochloride |
|
++
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Lurasidone |
|
++++
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Levosulpiride |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Pridopidine |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Metoclopramide |
|
✔
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Molindone HCl |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Sulpiride |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Perospirone |
|
++++
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Perospirone HCl |
|
++++
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Phenothiazine |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Pimozide |
+
Dopamine D1 receptor, Ki: 6600 nM
|
+++
Dopamine D2 receptor, Ki: 3.0 nM
|
++++
Dopamine D3 receptor, Ki: 0.83 nM
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Rotundine |
++
D1 receptor, IC50: 166 nM
|
+
D2 receptor, IC50: 1.47 μM
|
+
D3 receptor, IC50: 3.25 μM
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Domperidone |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| ONC206 |
|
✔
|
|
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Pimethixene maleate |
++
Dopamine D1 Receptor, pKi: 6.37
|
+++
Dopamine D2 Receptor, pKi: 8.19
|
|
++
Dopamine D4.4 Receptor, pKi: 7.54
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Loxapine succinate |
++
D2 receptor (Human), Ki: 62 nM
D1 receptor (human), Ki: 26 nM
|
++
D2 receptor (bovine), Ki: 26 nM
D2 receptor (human), Ki: 24 nM
|
|
+++
D4 receptor (human), Ki: 7.5 nM
|
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Chlorprothixene |
+++
|
+++
|
+++
|
|
+++
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| SCH-23390 HCl |
++++
D1 dopamine receptor, Ki: 0.2 nM
|
|
|
|
++++
D5 dopamine receptor, Ki: 0.3 nM
|
|
|
|
{[allProObj[0].p_purity_real_show]} |
| MPP+ iodide |
|
|
|
|
|
✔
|
|
|
{[allProObj[0].p_purity_real_show]} |
| σ1 Receptor antagonist-1 |
|
|
|
|
|
+
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Benztropine mesylate |
|
|
|
|
|
++
|
|
|
{[allProObj[0].p_purity_real_show]} |
| Azaperone |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Ziprasidone HCl |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Paliperidone |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Alizapride HCl |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Amisulpride |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
| Quetiapine hemifumarate |
|
|
|
|
|
|
✔
|
Adrenergic Receptor
|
{[allProObj[0].p_purity_real_show]} |
| Clozapine N-oxide |
|
|
|
|
|
|
✔
|
|
{[allProObj[0].p_purity_real_show]} |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
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