三叶豆紫檀苷 /Trifolirhizin
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货号：A466656
同义名：
红车轴草根甙
/ (–)-Maackiain-3-O-glucoside;Sophojaponicin B1
Trifolirhizin is purified from the roots of sophora flavescens L. that possesses potential anti-inflammatory and anti-cancer activities.
Trifolirhizin 化学结构
Trifolirhizin 3D分子结构
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Trifolirhizin 纯度/质量文件 产品仅供科研
货号：A466656
标准纯度：
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产品说明书
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Trifolirhizin 质控信息
Hexylresorcinol
+++
diphenolase, IC50: 0.85 μM
++
monophenolase, IC50: 1.24 μM
+++
monophenolase, IC50: 0.85 μM
diphenolase, IC50: 0.85 μM
99%+
Aloin
✔
98%
Arbutin
+
tyrosinase, IC50: 1.09 mM
98%
Monobenzone
✔
98%
Deoxyarbutin
++++
98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
Trifolirhizin 生物活性
描述
Trifolirhizin, a pterocarpan flavonoid, was isolated from the roots of Sophora flavescens. Trifolirhizin not only dose-dependently inhibited LPS-induced expression of pro-inflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) but also inhibited lipopolysaccharide (LPS)-induced expression of cyclooxygenase-2 (COX-2). In addition, trifolirhizin showed in vitro inhibitory effects on the growth of human A2780 ovarian and H23 lung cancer cells[2] [3] [4]
Trifolirhizin 参考文献
[1] Yang N, Liang B, et al. The Sophora flavescens flavonoid compound trifolirhizin inhibits acetylcholine induced airway smooth muscle contraction. Phytochemistry. 2013 Nov;95:259-67.
[2] Zhou H, Lutterodt H, Cheng Z, Yu LL. Anti-Inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots. J Agric Food Chem. 2009;57(11):4580-4585
[3] Lu X, Ma J, Qiu H, Yang L, Cao L, Shen J. Anti-proliferation effects of trifolirhizin on MKN45 cells and possible mechanism. Oncol Rep. 2016;36(5):2785-2792
[4] Yang N, Liang B, Srivastava K, et al. The Sophora flavescens flavonoid compound trifolirhizin inhibits acetylcholine induced airway smooth muscle contraction. Phytochemistry. 2013;95:259-267
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Trifolirhizin 实验方案
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总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.24mL
0.45mL
0.22mL
11.20mL
2.24mL
1.12mL
22.40mL
4.48mL
2.24mL
Trifolirhizin 技术信息
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