Tyrosinase-IN-16是一种高效的酪氨酸酶 (Tyrosinase) 抑制剂，Ki 值为 470 nM，能够有效抑制 B16F10 细胞的生长，在 20 μM 浓度下抑制率超过 90%，适用于黑色素生成抑制和抗癌研究。

Methyl 3-(2,4-dihydroxyphenyl)propionate, a natural product isolated and purified from the herbs of Juniperus formosana, has inhibitory effects on tyrosinase, antioxidant ability, and lightening effect of ultraviolet B (UVB)-induced hyperpigmentation.

hTYR/AbTYR-IN-1是一种 hTYR/AbTYR 双重抑制剂，对 hTYR 和 AbTYR 的 IC50 值分别为 5.4 μM 和 3.52 μM。

β-Tocopherol是维生素 E 的一种类似物，具有抗氧化作用，并能抑制酪氨酸酶活性和黑色素合成。该化合物还能够防止 d-α-Tocopherol 引起的细胞生长抑制及 PKC 活性降低，广泛用于皮肤美白和抗衰老的研究。

(R)-Trolox是一种维生素 E 类似物，为竞争性酪氨酸酶抑制剂，Ki 值为 0.83 mM，ID50 值为 1.88 mM，具有比 (S) 对映异构体更高的酪氨酸酶亲和力（Ki 值为 0.61 mM）。

Kojic acid dipalmitate是一种酪氨酸酶 (tyrosinase) 抑制剂，用于皮肤美白研究，具有竞争性抑制作用。

2,4-Dihydroxyhydrocinnamic Acid shows tyrosinase inhibition activity when mixed with l-ascorbic acid, it is a natural product isolated and purified from the herbs of Juniperus formosana.

3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth.

4-Butylresorcinol, a phenol derivative, is an inhibit of tyrosinase with IC50 of 11.27 μM.

Norartocarpetin 是一种酪氨酸酶抑制剂，具有较强的抑制活性，IC50 为 0.47 μM。它作为一种抗褐变剂可用于食品体系的研究，对肺癌细胞 (NCI-H460) 也具有显著的抗癌活性，IC50 为 22 μM。

Tyrosinase-IN-2是一种有效的超长链脂肪酸 1 (ELOVL1) 酶抑制剂，能抑制黑色素合成，适用于皮肤美白剂的开发研究，并可用于延缓食物中的酶促褐变。

Kushenol A, a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors isolated and purified from the roots of Sophora flavescens Ait., exhibits inhibitory activity against sodium-dependent glucose cotransporter 2(SGLT2 and shows selective alpha-glucosidase inhibitory activity.

Benzylacetone is an aromatic compound from agarwood[1]. Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity， with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively[2]. Benzylacetone has appetite-enhancing and locomotor-reducing effects[3].

Kojic acid is a chelation agent produced by several species of fungi.

Deoxyarbutin is a reversible inhibitor of tyrosinase with IC50 of 50 nM.

Oxyresveratrol is a naturallly occuring stilbenoid found in the heartwood of Artocarpus lakoocha, which works as a potent tyrosinase inhibitor and also possesses anti-proliferative, anti-inflammatory, and cardioprotective properties.

Arbutin is an inhibitor of tyrosinase with IC50 of 1.09 mM and can prevent the formation of melanin. It is a glycosylated hydroquinone found in the leaves of arctostaphylos uvaursi.

Methyl cinnamate is the methyl ester of cinnamic acid found naturally in a variety of plants. It could be used in the flavor and perfume industries.

Aloin A, an anthracycline from aloe plants, can be used as a chemopreventive factor with antineoplastic activity. It exhibits inhibition of phosphodiesterase and tyrosinase.

Fumaric acid a reversible inhibitor of tyrosinase.