Hesperidin | Hesperetin 7-rutinoside;Cirantin;USAF CF-3;Hesperitin-7-rhamnoglucoside;NSC 44184;Hesperidoside | 二氢黄酮甙 | Additive and Auxiliary Reagent | Plant Standard | Sugar | Vitamin

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橙皮苷 /Hesperidin {[allProObj[0].p_purity_real_show]}

货号：A154091 同义名： 二氢黄酮甙 / Hesperetin 7-rutinoside;Cirantin

Hesperidin is a flavanone glycoside which can be extracted in citrus fruits.

Hesperidin 化学结构
CAS号：520-26-3

Hesperidin 3D分子结构
CAS号：520-26-3

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Hesperidin 纯度/质量文件产品仅供科研

货号：A154091 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]; • JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]; • BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]; • J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]; • PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]; 更多 >

Hesperidin 生物活性

描述

Hesperidin is a flavonoid present in high concentration in citrus species and has numerous biological properties, principally antioxidant and anti-inflammatory^[3]. The AUC values for total hesperitin were 6.82 μM/h after administration of Bg1A-treated hesperidin and 7.91 μM/h after administration of pure hesperitin. In AD mice,after a relatively short-term treatments of 10 days, hesperidin (100 mg/kg) significantly ameliorated deficits in nesting and in social interactive behaviors, and attenuated β-amyloid deposition and microglial activation in brain. Low concentration of hesperitin (0.1 μM) scavenge reactive oxygen species and activate Akt in PC12 cells and increase seladin-1 secondary to estrogen signaling.

Hesperidin 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03482401	Breast Cancer	Not Applicable	Active, not recruiting	June 1, 2019	Spain ... 展开 >> Hospital General Universitario Reina Sofía Murcia, Spain, 30003 收起 <<
NCT03372109	Body Weight Changes	Not Applicable	Completed	-	United States, Florida ... 展开 >> Life Extension Clinical Research, Inc. Fort Lauderdale, Florida, United States, 33308 收起 <<
NCT01477281	Chronic Venous Insufficiency ... 展开 >> Disease 收起 <<	Phase 3	Unknown	August 2012	-

Hesperidin 参考文献

[1]Saiprasad G, Chitra P, et al. Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis. Eur J Cancer. 2014 Sep;50(14):2489-507.

[2]Hamdan DI, Mahmoud MF, et al. Effect of hesperidin and neohesperidin from bittersweet orange (Citrus aurantium var. bigaradia) peel on indomethacin-induced peptic ulcers in rats. Environ Toxicol Pharmacol. 2014 May;37(3):907-15.

[3]Tejada S, Pinya S, Martorell M, Capó X, Tur JA, Pons A, Sureda A. Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus. Curr Med Chem. 2018;25(37):4929-4945. doi: 10.2174/0929867324666170718104412. PMID: 28721824.

Hesperidin 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.64mL

0.33mL

0.16mL

8.19mL

1.64mL

0.82mL

16.38mL

3.28mL

1.64mL

Hesperidin 技术信息

CAS号	520-26-3
分子式	C₂₈H₃₄O₁₅
分子量	610.561

别名	二氢黄酮甙 ;Hesperetin 7-rutinoside;Cirantin;USAF CF-3;Hesperitin-7-rhamnoglucoside;NSC 44184;Hesperidoside
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度

DMSO: 105 mg/mL(171.97 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03482401	Breast Cancer	Not Applicable	Active, not recruiting	June 1, 2019	Spain ... 展开 >> Hospital General Universitario Reina Sofía Murcia, Spain, 30003 收起 <<
NCT03372109	Body Weight Changes	Not Applicable	Completed	-	United States, Florida ... 展开 >> Life Extension Clinical Research, Inc. Fort Lauderdale, Florida, United States, 33308 收起 <<
NCT01477281	Chronic Venous Insufficiency ... 展开 >> Disease 收起 <<	Phase 3	Unknown	August 2012	-
NCT01110512	Venous Insufficiency	Phase 3	Unknown	March 2011	Brazil ... 展开 >> Lal Clínica Pesquisa e Desenvolvimento Ltda Not yet recruiting Valinhos, SP, Brazil, 13270000 Contact: Alexandre Frederico, Psysician 55 19 3829-3822 alexandre@lalclinica.com.br 收起 <<
NCT02380144	Healthy	Not Applicable	Unknown	July 2017	Germany ... 展开 >> Chair of Plant Foodstuff Technology and Analysis (150d), University of Hohenheim Stuttgart, Baden-Württemberg, Germany, 70599 收起 <<
NCT03522896	Effect of Food on Postprandial... 展开 >> Hyperglycemia 收起 <<	Not Applicable	Completed	-	United Kingdom ... 展开 >> University of Leeds Leeds, United Kingdom, LS29JT 收起 <<
NCT02479568	Cardiovascular Risk Factors	Phase 3	Unknown	January 2018	Spain ... 展开 >> Technological Centre of Nutrition and Health (CTNS) Recruiting Reus, Tarragona, Spain, 43204 Contact: Rosa Maria Valls, PhD +34 636 944 723 estudis@ctns.cat Contact: Ignasi Papell, BSc +34 977 300 431 estudis@ctns.cat 收起 <<
NCT02907320	Venous Disease Classification ... 展开 >>(CEAP): C2 or C3 收起 <<	Phase 2	Withdrawn	May 2018	-
NCT03032861	Intestinal Diseases	Not Applicable	Completed	-	Brazil ... 展开 >> Sao Paulo State University "Julio de Mesquita Filho", Faculdade de Ciências Farmacêuticas Araraquara, Sao Paulo, Brazil, 14800-903 收起 <<
NCT03734510	Non Alcoholic Steatohepatitis	Not Applicable	Recruiting	February 1, 2019	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran (the Islamic Republic Of), Iran, Islamic Republic of, 1981619573 Contact: Azits Hekmatdoost, MD,PhD +982122357484 收起 <<
NCT00330096	Osteoporosis, Osteopenia	Phase 3	Completed	-	France ... 展开 >> Centre de Recherche en Nutrition Humaine. Laboratoire de Nutrition Humaine Clermont-Ferrand, Auvergne, France, 63009 收起 <<
NCT02927483	Chronic Venous Insufficiency	Phase 3	Unknown	June 2017	-
NCT02610491	Metabolic Syndrome ... 展开 >> Obesity 收起 <<	Phase 2	Completed	-	Netherlands ... 展开 >> MUMC+ Maastricht, Limburg, Netherlands, 6221EG 收起 <<
NCT03734835	Metabolic Syndrome	Not Applicable	Recruiting	March 1, 2019	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran (the Islamic Republic Of), Iran, Islamic Republic of, 1981619573 Contact: Azits Hekmatdoost, MD,PhD +982122357484 收起 <<
NCT00545116	Osteopenia Os... 展开 >>teoporosis 收起 <<	Phase 2	Completed	-	Malaysia ... 展开 >> Hospital of UKM, National University of Malaysia Kuala Lumpur, Malaysia, 56000 收起 <<
NCT03377153	Non Alcoholic Steatohepatitis	Not Applicable	Recruiting	March 20, 2018	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran, Islamic Republic of Contact: Azits Hekmatdoost 收起 <<
NCT03737422	Metabolic Syndrome	Not Applicable	Recruiting	December 1, 2018	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran, Islamic Republic of Contact: azita hekmatdoost, MD,PhD 收起 <<
NCT03377140	Non Alcoholic Steatohepatitis	Not Applicable	Recruiting	March 20, 2018	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran, Islamic Republic of Contact: Azits Hekmatdoost 收起 <<
NCT03734874	Metabolic Syndrome	Not Applicable	Recruiting	December 1, 2018	Iran, Islamic Republic of ... 展开 >> National Nutrition and Food Technology Research Institute Recruiting Tehran, Iran, Islamic Republic of Contact: azita hekmatdoost, MD,PhD 收起 <<
NCT00914251	Endothelial Dysfunction ... 展开 >> Metabolic Syndrome 收起 <<	Phase 2	Unknown	December 2010	Italy ... 展开 >> University of Rome Tor Vergata Recruiting Rome, Italy, 00133 Contact: Stefano Rizza, MD rizza@med.uniroma2.it Principal Investigator: Stefano Rizza, MD Sub-Investigator: Manfredi Tesauro, MD Sub-Investigator: Davide Lauro, MD 收起 <<
NCT03471910	Venous Insufficiency	Phase 4	Completed	-	Brazil ... 展开 >> Centro Universitário Serra dos Órgãos - UNIFESO Teresópolis, RJ, Brazil, 25964004 收起 <<
NCT01773486	Obesity Insul... 展开 >>in Resistance 收起 <<	Phase 2	Withdrawn(Not funded)	-	United States, Maryland ... 展开 >> University of Maryland Baltimore, Maryland, United States, 21201 收起 <<
NCT01881204	Osteoporosis, Postmenopausal	Not Applicable	Completed	-	United States, Indiana ... 展开 >> Purdue University West Lafayette, Indiana, United States, 47907 收起 <<

橙皮苷 /Hesperidin {[allProObj[0].p_purity_real_show]}

Hesperidin 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Hesperidin 质控信息

Hesperidin 生物活性

Hesperidin 临床研究

Hesperidin 参考文献

Hesperidin 实验方案

Hesperidin 技术信息

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橙皮苷 /Hesperidin {[allProObj[0].p_purity_real_show]}

Hesperidin 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Hesperidin 质控信息

Hesperidin 生物活性

Hesperidin 临床研究

Hesperidin 参考文献

Hesperidin 实验方案

Hesperidin 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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