Fangchinoline is an isolate of Stephania tetrandra and has anticancer activity through induction of G1 arrest in breast cancer cells.
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HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
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Accessible (Haz class 3, 4, 5 or 8), International
Fangchinoline, as a natural product, has the characteristics of enhancing immune function, low toxicity and good liver protection features. Fangchinoline inhibited the proliferation of A375 and A875 cells activity with IC50 values of 12.41 and 16.20 µM. Fangchinoline significantly decreased the invasion and migration potential of A375 cells and A875 cells in a dose-dependent manner [3]. Fangchinoline inhibited the growth of MDA-MB-231 cells in concentration-dependent manner and it induced MDA-MB-231 cell apoptosis[4]. In addition, fangchinoline suppressed the growth of subcutaneous osteosarcoma tumors in Balb/c mice subcutaneously injected with osteosarcoma cells[5].
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