产品说明书
Fangchinoline
 |
同义名 : | 防己醇灵 ;7-O-Demethyltetrandrine;NSC 77036;Hanfangchin B |
| CAS号 : | 436-77-1 | |
| 货号 : | A334684 | |
| 分子式 : | C37H40N2O6 | |
| 纯度 : | 98% | |
| 分子量 : | 608.723 | |
| MDL号 : | MFCD00221726 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 50 mg/mL(82.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Fangchinoline, as a natural product, has the characteristics of enhancing immune function, low toxicity and good liver protection features. Fangchinoline inhibited the proliferation of A375 and A875 cells activity with IC50 values of 12.41 and 16.20 µM. Fangchinoline significantly decreased the invasion and migration potential of A375 cells and A875 cells in a dose-dependent manner [3]. Fangchinoline inhibited the growth of MDA-MB-231 cells in concentration-dependent manner and it induced MDA-MB-231 cell apoptosis[4]. In addition, fangchinoline suppressed the growth of subcutaneous osteosarcoma tumors in Balb/c mice subcutaneously injected with osteosarcoma cells[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.64mL 0.33mL 0.16mL |
8.21mL 1.64mL 0.82mL |
16.43mL 3.29mL 1.64mL |
| 参考文献 |
|---|