C646 是一种选择性竞争性的乙酰化酶histone acetyltransferase p300 抑制剂，Ki 值为 400 nM，对其他乙酰转移酶的作用较小。

SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor with IC50 of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively.

GNE-781 是一种有效、口服活性和选择性的 CBP 抑制剂，在 TR-FRET 测定中的 IC50 为 0.94 nM。GNE-781 还抑制 BRET 和 BRD4 (1)，IC50 值分别为 6.2 nM 和 5100 nM。

Histone Acetyltransferase inhibitor II, insulin producing cells capable of secreting blood glucose regulating hormones, specially insulin, in response to physiological signals, method of production of said cells and uses thereof.

NEO2734 is an orally dual p300/CBP and BET bromodomain inhibitor with IC50 values of <30 nM for both p300/CBP and BET bromodomains.

A 485 is a potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor with IC50 of 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively.

CPI-637 is an efficient inhibitor of CBP/EP300 bromodomain with IC50 of 0.03 ± 0.01μM.

PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein (CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.

Anacardic acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity,prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

PRI-724 is a selective inhibitor of the CBP/β-catenin interaction.

Curcumin (Diferuloylmethane) 是一种天然酚类化合物，是乙酰转移酶 p300/CREB 结合蛋白的特异性抑制剂，抑制组蛋白/非组蛋白的乙酰化和组蛋白乙酰转移酶依赖的染色质转录。Curcumin 对 NF-κB 和 MAPKs 有抑制作用，具有抗炎、抗氧化、抗增殖和抗血管生成等药理作用。

Nordihydroguaiaretic Acid is a naturally occuring mTORC1 inhibitor.

I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that targets the CBP/p300 bromodomains.