NI 42 is a selective inhibitor of BRPF with Kd values of 40, 210 and 943 nM for BRPF1B, 2 and 3, respectively. It also exhibits modest activity at BRD9 (Kd = 1130 nM).

GSK5959 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with IC50 ~ 80 nM.

GSK6853是一种有效而选择性的RPF1乙酰赖氨酸（pKd=9.5）抑制剂，与其他乙酰赖氨酸相比，选择性高达1600倍。

PFI-4 selectively inhibits BRPF1 bromodomain with IC50 of 80 nM.

OF-1 is an inhibitor of the proteins BRPF1B (Kd = 100 nM) and BRPF2 (Kd = 500 nM) bromodomain.