Chlorprothixene is an antagonist of multiple receptors including 5-HT2 (Ki = 3.4 nM), D1 (Ki = 18 nM), D2 (Ki = 18 nM), D3 (Ki = 4.56 nM), H1 (Ki = 3.75 nM), muscarinic acetylcholine receptors, α1-Adrenergic.

Lurasidone functions as an antagonist of the dopamine D2 and D3 receptors, the serotonin 5-HT2A and 5-HT7 receptors, the α2C-adrenergic receptor, and as a partial agonist of the serotonin 5-HT1A receptor.

Pimethixene maleate是一种抗组胺药物，主要用于过敏性疾病的研究。它通过阻断 H1 受体，对过敏反应有显著的抑制作用。

Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00).

Ropinirole HCl selectively inhibit dopamine D2 receptor with Ki of 29 nM. It is used for the treatment of spontaneous parkinson's disease.

Rotundine is antagonist for domapmine D1 receptor(Ki = 124 nM) and has a lower binding activity of domapmine D2 receptor and domapmine D3 receptor. It can also inhibit 5-HT1A (Ki = 340 nM).

Olanzapine is a multiple-target antagonist for 5-HT2A receptors and D2 dopamine receptors, as well as muscarinic M3 receptor.

Phenothiazine, a dopamine2 (D2) receptor antagonist, could reduce the expression of dopamine in the brain.

Levosulpiride, an atypical antipsychotic, can selectively inhibit D2 receptor and it is the (S)-enantiomer of sulpiride.

Pridopidine exhibits high affinity towards sigma 1 receptor (S1R) (Ki = 70-80 nM) which can counteract the effects of excessive or insufficient dopaminergic transmission and it can used as a dopamine (DA) stabilizer.

ONC206 是 ONC201 的类似物。ONC206 是一种选择性拮抗剂，对多巴胺 D2 类受体 (DRD2/3/4) 具有纳摩尔效力。ONC206 表现出广谱抗肿瘤活性。

Molindone HCl, the salt form of molindone which is a dopamine receptor antagonist, can be used in the treatment of schizophrenia and act as a therapeutic antipsychotic.

Sulpiride is a typical antipsychotic drug that binds to dopamine D2 receptor. Sulpiride is an effective treatment for schizophrenia and depressive disorder.

Prochlorperazine dimaleate is an antagonist of dopamine (D2) receptor with Ki value of 4.7 nM.

Metoclopramide is an antagonist of dopamine D2 and is commonly used as an antiemetic.

Loxapine succinate salt is an multiple-target antagonist of both D2/D4 dopamine receptor and 5-HT2A/2B, 5-H7 serotonin receptor, used as an antipsychotic agent.

Trifluoperazine is a typical antipsychotic of the phenothiazine chemical class.

In CHO cells expressing human 5-HT1A receptors, perospirone shows a high affinity (Ki = 0.72 nM), and exhibits partial agonistic efficacy.

Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; also inhibits STAT3 and STAT5.