NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.

Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites, which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission.

ANO1-IN-1是一种选择性 ANO1 通道阻断剂，抑制胶质瘤细胞增殖，IC₅₀ 分别为 2.56 μM 和 15.43 μM，适用于神经胶质瘤的研究。

Afoxolaner是一种针对 γ-氨基丁酸受体（GABA） 和谷氨酸受体 (glutamate receptors)的药物，用于控制寄生虫和螨类，广泛用于兽医学。

Ani 9 is selective TMEM16A blocker with IC50 of 77 nM.

Adjudin exhibits anti-inflammatory properties by suppression of NF-κB p65 nuclear translocation and DNA binding activity as well as ERK MAPK phosphorylation.

Eact is an activator of TMEM16A calcium-activated chloride channel (CaCC) with EC50 of 3 μM. It is also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM).

R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels.

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).

Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.

(Rac)-Shikonin是一种天然产物，具有强效的抗肿瘤活性，能够绕过癌症耐药性。

Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 μM, it's a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc..

NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 µM and inhibitor of cyclooxygenase (IC50 = 8 µM).

Fluralaner (INN) 是一种全身性杀虫剂和杀螨剂，通过强效阻断 GABA 和 L-glutamate氯离子通道发挥作用。

Endovion is a blocker of both VRAC and CaCC with IC50 value around 400nM for blocking swelling-activated anion currents in HEK293 cells.

Fluxametamide 是一种广谱杀虫剂和 GABA 及谷氨酸门控氯离子通道拮抗剂，其对 M. domestica 中的 GABACl 和 GluCl 的 IC50 值分别为 1.95 nM 和 225 nM。

DCPIB是一种体积调节性阴离子通道（VRAC）抑制剂，能有效抑制细胞的钠钾通道和氯电流。它在细胞肿胀和离子通道研究中具有应用潜力。

9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.