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Fluralaner {[allProObj[0].p_purity_real_show]}

货号:A724974 同义名: A1443;AH252723

Fluralaner (INN) 是一种全身性杀虫剂和杀螨剂,通过强效阻断 GABA 和 L-glutamate氯离子通道发挥作用。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Fluralaner 化学结构 CAS号:864731-61-3
Fluralaner 化学结构
CAS号:864731-61-3
Fluralaner 3D分子结构
CAS号:864731-61-3
Fluralaner 化学结构 CAS号:864731-61-3
Fluralaner 3D分子结构 CAS号:864731-61-3
规格 价格 会员价 库存 数量
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Fluralaner 纯度/质量文件 产品仅供科研

货号:A724974 标准纯度: {[allProObj[0].p_purity_real_show]}
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Fluralaner 生物活性

描述 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
体内研究

On dogs treated with fluralaner in a simulated flea-infested environment, the efficacy in controlling fleas exceeds 99% consistently over 12 weeks, without adverse effects observed. Fluralaner ensures complete control over egg production, larval growth, and flea reproduction at concentrations below insecticidal levels. Its oral administration in dogs proves extremely efficient in eradicating fleas in such environments[1].[2].

体外研究

Fluralaner strongly curtails the reproductive capacity of fleas in vitro, halting egg production at as low as 25.0 ng/mL. Although it shows no effect on eggs, it has a larvicidal impact at very low concentrations (6.25 ng/mL)[1].

Fluralaner 参考文献

[1]Williams H, et al. Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in asimulated home environment. Parasit Vectors. 2014 Jun 19;7:275.

[2]Walther FM, et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1(-/-) Collies after oral administration. Parasit Vectors. 2014 Mar 6;7:86.

Fluralaner 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.80mL

0.36mL

0.18mL

8.99mL

1.80mL

0.90mL

17.98mL

3.60mL

1.80mL

Fluralaner 技术信息

CAS号864731-61-3
分子式C22H17Cl2F6N3O3
分子量 556.285
别名 A1443;AH252723;Fluralaner, trade name: Bravecto.
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度

DMSO: 190 mg/mL(341.55 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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