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Methyl Salicylate is a natural product produced by many species of plants, used as a fragrance, in foods and beverages, and in liniments.
(±)-Naproxen ((Rac)-Naproxen) 是 Naproxen 的外消旋体,作为一种 COX-1 和 COX-2 抑制剂,其 IC50 分别为 8.72 μM 和 5.15 μM。
Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
Racecadotril is an enkephalinase inhibitor with IC50 value of 4.5 μM, used as an antidiarrheal drug.
Clobetasol propionate is a corticosteroid with anti-inflammatory effect and is used to treat various skin disorders.
Medroxyprogesterone acetate, the acetate form of medroxyprogesterone which is a progesterone receptor agonist and a synthetic variant of the human hormone progesterone
Flufenamic Acid is a COX inhibitor and prevents formation of prostaglandins, binds to and reduce the activity of prostaglandin F synthase and activate TRPC6, it is a NSAID drug.
Piroxicam is a selective COX1 inhibitor with anti-inflammatory effects.
Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. It's a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.
Diclofenac sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.
Sulfasalazine(NSC 667219) 是一种抗风湿剂,用于类风湿性关节炎和溃疡性结肠炎的研究。它抑制 NF-κB 活性并作为 I 型铁死亡诱导剂。
Etodolac is a non-selective inhibitor of COX with IC50 of 53.5 nM, it is a non-steroidal anti-inflammatory compound.
Voriconazole is a second-generation triazole antifungal used to treat serious fungal infections by inhibiting the synthesis of ergosterol, the major sterol of the fungal cell membrane.
Tropicamide is a mAchR M4 antagonist, used to dilate the pupil and help with examination of the eye.
Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes.
4-Biphenylacetic acid is used in the synthesis of gastrosparing non-steroidal antiinflammatory drug as a potential non-steroidal antiinflammatory agent.
Mometasone furoate is a prodrug of mometasone with high affinity for glucocorticoid receptor.
RG108 is a DNA methyltransferase inhibitor with IC50 of 115 nM.
Fenretinide, the deriverative of retinoid, can bind to retinoic acid receptors (RAR) and induce cell death.
Rolipram is a selective inhibitor of phosphodiesterases PDE 4, especially the PDE 4B with IC50 of 130 nM while IC50 for PDE4D is 240 nM, it's an anti-inflammatory agent.
Tags: 抗炎 | Anti-inflammation | 小分子阳性药 | Small Molecule Positive Drug | 其他抑制剂/激动剂 | Other Inhibitors/Agonists | 抗炎 相关产品
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