Mometasone furoate | 糠酸莫米松 | Sch32088 | Glucocorticoid Receptor Agonist

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糠酸莫美他松 /Mometasone furoate

货号：A133834 同义名： 糠酸莫米松 / Sch32088

Mometasone furoate是一种前药，具有高亲和力与糖皮质激素受体结合，用于治疗皮肤炎症、慢性湿疹及气道炎症等。

Mometasone furoate 化学结构
CAS号：83919-23-7

Mometasone furoate 3D分子结构
CAS号：83919-23-7

规格	价格	库存
100μL*10mM(DMSO)	￥109随货￥79	咨询
250μL*10mM(DMSO)	￥99随货￥69	咨询
500μL*10mM(DMSO)	￥159随货￥119	咨询
10mM*1mL(DMSO)	￥280	咨询
25mg	￥255	咨询
50mg	￥315	咨询
100mg	￥504	咨询
250mg	￥781	咨询
500mg	￥1449	咨询

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Mometasone furoate 纯度/质量文件产品仅供科研

货号：A133834 标准纯度：产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Neuron, 2025. Ambeed. [ A1440350 ]; • Nature Communications, 2025, 16, 996. Ambeed. [ A111960 , A505336 ]; • JACS, 2025. Ambeed. [ A349578 , A2270125 ]; • PLoS Biol., 2025, 23(2): e3002961. Ambeed. [ A181909 ]; • Redox Rep., 2025, 30(1): 2454887. Ambeed. [ A1155014 ]; 更多 >

Mometasone furoate 生物活性

描述

Mometasone furoate is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. Mometasone furoate acts as a corticosteroid agent and used for topical applications in chronic skin eczema and airway inflammation management of asthma in vivo. Mometasone furoate exhibits high potency with greater anti-inflammatory activity and a longer duration of action than betamethasone. The molecular biotransformation of mometasone furoate in the skin results in a lower affinity with dermal cells than epidermal cells, which contributes to its low atrophogenicity^[3]. Breast cancer patients receiving MF (Mometasone Furoate) during PMRT (postmastectomy radiation) experienced significantly reduced rates of moist desquamation in comparison with a control cream^[4].

Mometasone furoate 参考文献

[1]Magari M, Ikeda M, et al. Suppressive effects of mometasone furoate on an antigen-specific IgE antibody response and production of IL-4 in mice. Immunopharmacol Immunotoxicol. 2006;28(3):491-500.

[2]Tsumuro T, Ogawa M, et al. Effects of mometasone furoate on a rat allergic rhinitis model. Eur J Pharmacol. 2005 Nov 7;524(1-3):155-8.

[3]Spada F, Barnes TM, Greive KA. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. Australas J Dermatol. 2018 Aug;59(3):e168-e174

[4]Ho AY, Olm-Shipman M, Zhang Z, Siu CT, Wilgucki M, Phung A, Arnold BB, Porinchak M, Lacouture M, McCormick B, Powell SN, Gelblum DY. A Randomized Trial of Mometasone Furoate 0.1% to Reduce High-Grade Acute Radiation Dermatitis in Breast Cancer Patients Receiving Postmastectomy Radiation. Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):325-333

Mometasone furoate 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.92mL

0.38mL

0.19mL

9.59mL

1.92mL

0.96mL

19.18mL

3.84mL

1.92mL

Mometasone furoate 技术信息

CAS号	83919-23-7
分子式	C₂₇H₃₀Cl₂O₆
分子量	521.429

别名	糠酸莫米松 ;Sch32088
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,2-8°C

溶解方案

细胞实验：

DMSO: 50 mg/mL(95.89 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

摩尔计算器

计算溶液所需的质量，体积或浓度。 Ambeed 摩尔浓度计算器基于以下方程式：

浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)=质量 (g)

浓度

体积

分子量

质量

糠酸莫美他松 /Mometasone furoate

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Mometasone furoate 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Mometasone furoate 质控信息

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Mometasone furoate 参考文献

Mometasone furoate 实验方案

Mometasone furoate 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

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确认信息

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