CAY 10465是一种高亲和性的芳香烃受体（AhR）激动剂，对雌激素受体无作用。它在研究AhR信号通路和相关疾病中具有重要意义。

Brevifolincarboxylic acid 是从蓼属植物提取的，对芳烃受体 (AhR) 有抑制作用，也是 α-葡萄糖苷酶的抑制剂，IC50 值为 323.46 μM。

GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.

ANI-7是一种 AhR 通路激活剂，能够通过激活 AhR 途径抑制多种癌细胞的生长，尤其对 MCF-7 乳腺癌细胞具有选择性抑制作用，GI50 为 0.56 μM，适用于乳腺癌和其他癌症的研究。

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

Formononetin can act as an agonist of aryl hydrocarbon receptor (EC50 = 130 nM) and has prevention of breast cancer, prostate cancer and colon cancer. Formononetin could be extracted from the bark of Ononis natrix L..

Potassium 1H-indol-3-yl sulfate是一种内源性代谢产物，通常用于代谢研究和病理分析中，以评估其在不同代谢通路中的作用。

MeBIO是一种有效的 AhR 激动剂，其 IC50 对 GSK-3 和 CDK1/cyclin b 分别为 44 μM 和 55 μM，对 GSK-3β 无效。

PDM 11 is a derivative of the antioxidant trans-resveratrol.

SGA360通过 AHR 依赖性的方式抑制炎症相关的 SAA1 通路，但其机制无需 AHR 绑定到同源响应元件 (XRE)。SGA360 具有在炎症和免疫相关疾病中的研究潜力，特别适用于 AHR 介导的信号通路研究。

AHR antagonist 5 free base是一种选择性、口服活性的芳烃受体 (AHR) 抑制剂，能够阻止 AHR 从细胞质转移到细胞核。该化合物对 AHR 具有高度选择性，并在抗癌研究中展现了重要的应用潜力。

Tapinarof是一种芳烃受体 (AhR) 激动剂，具有消除小鼠皮肤炎症的作用，可能用于皮肤病研究。

D-Kynurenine是 D-色氨酸的代谢产物，可作为健尿酸 (KYNA) 和 3-羟基犬尿氨酸的前体，激活 G 蛋白偶联受体 GPR109B，并用作 D-氨基酸氧化酶荧光分析的底物，还可通过激活芳香烃受体 (AHR) 促进上皮细胞向间充质细胞的转化。

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

ITE is an AhR agonist with Ki value of 3nM, and also inhibits TGF-β-induced human myofibroblast differentiation.

1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).

L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway .

Galangin functions as an antagonist of the aryl hydrocarbon receptor and also inhibits CYP1A1 (IC50 = 1 μM). It belongs to flavonoids and can be extracted from the rhizome of Zingiber officinale Roscoe with anti-inflammatory properties.

Indole-3-Carbinol is a naturally occuring plant hormone found in cruciferous vegetables, which can both inhibit carcinogenesis in several animal species and enhance tumor incidence if administered at a post-initiation stage.