A2A receptor antagonist 1是一种腺苷 A2A 受体拮抗剂，同时对 A1 受体也具有拮抗作用。它在研究 A2A 受体相关信号通路及其在各种疾病中的治疗应用中具有潜力。

MIPS521是一种腺苷受体（A1AR）的正向变构调节剂，能有效调节腺苷水平。其潜力在于减轻疼痛的研究，特别是在大鼠体内显示了显著的效果。

DPCPX is a potent and selective A1 adenosine receptor antagonist, both in vitro and in vivo, with Ki of 3.9 nM for human A1.

Vipadenant is an adenosine antagonist with Ki of 1.3 nM and 68 nM for A2A and A1, respectively. Vipadenant is a selective A2A receptor antagonist with Ki values of 1.3, 68, 63, and 1,005 nM for A2A, A1, A2B, and A3 receptors, respectively, used in development for for Parkinson's disease.

PD117519 is an adenosine agonist.

PSB-1115是一种选择性 A2B 腺苷受体拮抗剂，能抑制三硝基苯磺酸 (TNBS) 诱导的乙酰胆碱 (ACh) 收缩抑制现象。

Tozadenant is a selective adenosine A2A receptor antagonist with Ki values of 11.5 nM on human A2A and 6 nM on rhesus A2A, which can improve motor function in animal models of Parkinson's disease.

Preladenant is a highly selective and competitive A2A receptor antagonist with Ki value of 1.1nM, used in trials studying the treatment of brain diseases, such as parkinson disease, movement disorders, antipsychotic agents and parkinsonian disorders.

SCH-442416 is a selective adenosine A2A receptor antagonist. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). It displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).

CPI-444 is an orally administered antagonist of the adenosine A2A receptor. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs).

IB-MECA is an agonist of the adenosine A3 receptor with EC50 values of 0.11 μM. IB-MECA is a potent and selective A3 adenosine receptor agonist with Ki value of 1.1, 54 and 56 nM for A3, A1 and A2A receptors, respectively, which possessing cardioprotective effect and reduces infarct size upon reperfusion in rats.

BAY 2416964 is an antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM.

Tecadenoson is a selective A1 adenosine receptor agonist.

Taminadenant is an antagonist of adenosine receptor.

2-Chloro-N6-cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist with Ki of 0.8 nM for human A1.

CGS 15943 is a potent adenosine receptor antagonist with Ki values of 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively.

AZD4635 is an A2AR antagonist which can reverse adenosine mediated T cell suppression.

MRS 1754 is a selective adenosine A2B receptor antagonist with Ki of 1.97 nM for hA2B.

GS-6201（CVT-6883）是一种选择性的腺苷A2B受体拮抗剂，对人类腺苷A2B受体具有高亲和力和选择性（Ki=22 nM）。

AB928 is a dual A2aR/A2bR antagonist that inhibits A2aR and A2bR with an equilibrium binding constant of 1.4 and 2 nM, respectively.