LDN193189是一种有效的选择性BMP I型受体（BMP I）抑制剂，有效抑制BMP I型受体ALK2和ALK3的转录活性，IC50值分别为5 nM和30 nM。它用于研究骨形态发生蛋白信号传导，如进行性纤维发育性骨化症。

K02288 is an inhibitor of type I BMP receptor. It targeting ALK2, ALK1 and ALK6 with IC50 of 1.1, 1.8, 6.4 nM, respectively.

LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM with > 100 fold selectivity for ALK5, and also inhibits BMP6 (IC50=100 nM).

ML347 is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM and shows > 300-fold selectivity for ALK2 vs. ALK3.

LDN-212854 is an inhibitor of BMP and can inhibit ALK2 with IC50 of 1.3 nM. It is used to prevent heterotopic ossification.

DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/< 5 nM for ALK1/2/3 respectively and inactive on ALK5, BMPR2, AMPK and VEGFR2.

LDN-193189 2HCl is a potent and selective ALK2 and ALK3 inhibitor.