CCG-100602是一种选择性MRTF-A/SRF信号转导抑制剂，通过阻断MRTF-A的核定位，抑制纤维生成转录因子的活性，用于研究纤维化和相关疾病。

APS6-45是一种针对肿瘤细胞的校准抑制剂 (TCI)，通过干扰 RAS/MAPK 信号通路，具有抗肿瘤活性。

ML-097 (CID-2160985) 是一种泛 Ras 相关的 GTPases 激活剂，可以激活 Rac1、cell division cycle 42、Ras 和 Rab7。

CID44216842是一种新型的 GPR40 受体拮抗剂，用于治疗糖尿病及相关代谢疾病的研究中显示出应用前景。

BRD7-IN-1 是 BI7273 (BRD7/9 抑制剂) 的一种改良衍生物，通过与 VHL 配体连接形成 PROTAC VZ185。VZ185 对 BRD7 和 BRD9 的 DC50 值分别为 4.5 nM 和 1.8 nM。

Kobe2602 is an effective small-molecule compound inhibiting Ras–Raf interaction by SBDD exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.

CASIN is an inhibitor of GTPase Cdc42 with IC50 of 2 μM that can generat a rejuvenated phenotype of HSCs.

ARS-853 is an inhibitor of KRAS G12C with IC50 of 2.5 μM.

RBC8 is an inhibitor of GTPases RalA and RalB with IC50 of 3.5 μM in cell assay.

MDK-3017 is a K-Ras inhibitor, by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.

Kobe0065 inhibits the binding of H-Ras·GTP to c-Raf-1 RBD with Ki of 46 ± 13 μM.

FTI-277 HCl is an inhibitor of farnesyl transferase (FTase) and a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.

CMC2.24是一种口服活性的三羰基甲烷化合物，能够通过抑制 Ras 及其下游 ERK1/2 途径来抑制胰腺肿瘤的生长，同时作为锌依赖性 MMPs 的抑制剂，适用于抗癌、软骨内稳态调节及骨关节炎等疾病的研究。

Antineoplaston A10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.

1A-116 is a specific Rac1 inhibitor.

BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth similar to depletion of Ral by siRNA.

Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations and also leads to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells.

Rac1-IN-3 是一种 Rac1 抑制剂，IC50 为 46.1 μM。

MLS-573151是一种选择性 Cdc42 GTPase 抑制剂。它通过阻止 GTP 与 Cdc42 的结合来发挥作用，对其他 GTPase 家族成员如 Rab2 和 RhoA 无效。MLS-573151 在研究细胞迁移、增殖和相关癌症过程中具有潜在应用价值。

MRTX1133是一种高选择性的KRAS G12D抑制剂，专门针对KRAS G12D突变体，能够有效抑制其信号转导。