β,β-Dimethylacrylshikonin | Dimethylacrylshikonin;Isoarnebin I | HIF | Lithospermum | Quinones

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β,β-Dimethylacrylshikonin {[allProObj[0].p_purity_real_show]}

货号：A393692 同义名： Dimethylacrylshikonin;Isoarnebin I

Dimethylacrylshikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc. with anti-proliferate activity, is a promising agent for developing an improved strategy for radiotherapy against tumors.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

β,β-Dimethylacrylshikonin 化学结构
CAS号：24502-79-2

β,β-Dimethylacrylshikonin 3D分子结构
CAS号：24502-79-2

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β,β-Dimethylacrylshikonin 纯度/质量文件产品仅供科研

货号：A393692 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]; • JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]; • BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]; • J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]; • PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]; 更多 >

HIF 亚型比较

产品名称	HIF ↓ ↑	HIF1 ↓ ↑	PHD1 ↓ ↑	PHD2 ↓ ↑	PHD3 ↓ ↑	其他靶点	纯度
KC7F2	+ HIF-1α, IC50: 20 μM	+ HIF-1α, IC50: 20 μM					98%
Lificiguat	✔						99%+
BAY 87-2243	✔						99%+
PX-478·2HCl	✔						98%+
2-Methoxyestradiol	✔						98%
CAY10585	++ HIF, IC50: 4.4 μM					BCRP	97%
DMOG			✔				98%
FG 2216				++ PHD2, IC50: 3.9 μM			99%+
MK-8617			++++ PHD1, IC50: 1 nM	++++ PHD2, IC50: 1 nM	++++ PHD3, IC50: 14 nM		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

β,β-Dimethylacrylshikonin 生物活性

描述	Dimethylacrylshikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc. with anti-proliferate activity, is a promising agent for developing an improved strategy for radiotherapy against tumors.

β,β-Dimethylacrylshikonin 参考文献

[1]Kwak SY, Jeong YK, et al. β,β-Dimethylacrylshikonin sensitizes human colon cancer cells to ionizing radiation through the upregulation of reactive oxygen species. Oncol Lett. 2014 Jun;7(6):1812-1818.

[2]Wu YY, Wan LH, et al. Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo. Phytother Res. 2012 May;26(5):764-71.

β,β-Dimethylacrylshikonin 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.70mL

0.54mL

0.27mL

13.50mL

2.70mL

1.35mL

27.00mL

5.40mL

2.70mL

β,β-Dimethylacrylshikonin 技术信息

CAS号	24502-79-2
分子式	C₂₁H₂₂O₆
分子量	370.4

别名	Dimethylacrylshikonin;Isoarnebin I
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Store in freezer, under -20°C

溶解度

DMSO: 12 mg/mL(32.4 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

β,β-Dimethylacrylshikonin {[allProObj[0].p_purity_real_show]}

β,β-Dimethylacrylshikonin 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

β,β-Dimethylacrylshikonin 质控信息

β,β-Dimethylacrylshikonin 生物活性

β,β-Dimethylacrylshikonin 参考文献

β,β-Dimethylacrylshikonin 实验方案

β,β-Dimethylacrylshikonin 技术信息

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β,β-Dimethylacrylshikonin {[allProObj[0].p_purity_real_show]}

β,β-Dimethylacrylshikonin 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

β,β-Dimethylacrylshikonin 质控信息

β,β-Dimethylacrylshikonin 生物活性

β,β-Dimethylacrylshikonin 参考文献

β,β-Dimethylacrylshikonin 实验方案

β,β-Dimethylacrylshikonin 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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C

F

G

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β,β-Dimethylacrylshikonin 纯度/质量文件产品仅供科研