货号:A102794 同义名: Sophoradin;5-Epidihydrosophocarpine
Sophoridine is naturally occuring alkaloid found in the plant Sophora flavescens, which could suppresses cell growth of human medulloblastoma through the inhibition of the FoxM1, NF‑κB and AP‑1 signaling pathway.
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Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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免费溶解
描述 | Sophoridine is monomer alkaloids which extracts from Sophora alopecuroides L, is a potential antitumor natural product with high application value. Sophoridine exhibited remarkable inhibition effects to the growth of human pancreatic, gastric, liver, colon, gallbladder, and prostate carcinoma cells with IC50 values of about 20 μmol/L to 200 μmol/L[3]. Moreover, the cell proliferation of difference concentrations Sophoridine treated groups(134.62 ± 5.76%, 98.96 ± 4.88%, 80.26 ± 6.70% and 80.08 ± 5.65%) was significantly reduced compared with 0 μg/ml group. And Sophoridine had suppressed Hep G2 proliferation with dose-depend[4]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
4.03mL 0.81mL 0.40mL |
20.13mL 4.03mL 2.01mL |
40.26mL 8.05mL 4.03mL |
CAS号 | 6882-68-4 |
分子式 | C15H24N2O |
分子量 | 248.364 |
别名 | Sophoradin;5-Epidihydrosophocarpine;(-)-Sophoridine;Dihydro-5-episophocarpine |
运输 | 蓝冰 |
存储条件 |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 50 mg/mL(201.32 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |