产品说明书
Sophoridine
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同义名 : | Sophoradin;5-Epidihydrosophocarpine;(-)-Sophoridine;Dihydro-5-episophocarpine |
| CAS号 : | 6882-68-4 | |
| 货号 : | A102794 | |
| 分子式 : | C15H24N2O | |
| 纯度 : | 96% | |
| 分子量 : | 248.364 | |
| MDL号 : | MFCD00238686 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(201.32 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Sophoridine is monomer alkaloids which extracts from Sophora alopecuroides L, is a potential antitumor natural product with high application value. Sophoridine exhibited remarkable inhibition effects to the growth of human pancreatic, gastric, liver, colon, gallbladder, and prostate carcinoma cells with IC50 values of about 20 μmol/L to 200 μmol/L[3]. Moreover, the cell proliferation of difference concentrations Sophoridine treated groups(134.62 ± 5.76%, 98.96 ± 4.88%, 80.26 ± 6.70% and 80.08 ± 5.65%) was significantly reduced compared with 0 μg/ml group. And Sophoridine had suppressed Hep G2 proliferation with dose-depend[4]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.03mL 0.81mL 0.40mL |
20.13mL 4.03mL 2.01mL |
40.26mL 8.05mL 4.03mL |
| 参考文献 |
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