货号:A146452
同义名:
吡哆醇盐酸盐;维生素B6
/ Pyridoxol hydrochloride;Vitamin B6 hydrochloride
Pyridoxine HCI是维生素 B6 的一种形式,通过 Nrf-2/HO-1 通路表现抗氧化活性,用于神经退行性疾病和代谢性疾病的研究。
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描述 | Pyridoxine Hydrochloride is a water- soluble pyridine derivative. Pyridoxine exerted a protective potential against AD, attenuated ROS levels, decreased the expressions of cytoplasmic Nrf2, and upregulated whole-cell HO-1 expression[3]. Vitamin B6 (pyridoxine) is closely associated with the functions of the nervous, immune and endocrine systems. It also participates in the metabolic processes of proteins, lipids and carbohydrates. Pyridoxine deficiency may result in neurological disorders including convulsions and epileptic encephalopathy and may lead to infant abnormalities[4]. Moreover, vitamin B6 (Pyridoxine) significantly increased the amount of dream content participants recalled but did not significantly affect dream vividness, bizarreness, or color, nor did it significantly affect other sleep-related variables[5]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT00001166 | - | Completed | - | United States, Maryland ... 展开 >> National Eye Institute (NEI) Bethesda, Maryland, United States, 20892 收起 << | |
NCT00000638 | HIV Infections ... 展开 >> Tuberculosis 收起 << | Not Applicable | Completed | - | - |
NCT00642408 | Multiple Micronutrient Deficie... 展开 >>ncies During Pregnancy 收起 << | Phase 4 | Completed | - | Burkina Faso ... 展开 >> Centre Muraz, 2054, Avenue Mamadou KONATE Bobo-Dioulasso, Burkina Faso, BP 390 收起 << |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
4.86mL 0.97mL 0.49mL |
24.31mL 4.86mL 2.43mL |
48.63mL 9.73mL 4.86mL |
CAS号 | 58-56-0 |
分子式 | C8H12ClNO3 |
分子量 | 205.639 |
别名 | 吡哆醇盐酸盐;维生素B6 ;Pyridoxol hydrochloride;Vitamin B6 hydrochloride;Pyridoxine HCl |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Keep in dark place,Inert atmosphere,Room temperature |
溶解方案 |
DMSO: 50 mg/mL(243.14 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 50 mg/mL(243.14 mM) 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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动物实验配方 |