货号:A158758 同义名: 氧化白黎芦醇 / trans-Oxyresveratrol;trans-2',3,4',5-Tetramethoxystilbene
Oxyresveratrol is a naturallly occuring stilbenoid found in the heartwood of Artocarpus lakoocha, which works as a potent tyrosinase inhibitor and also possesses anti-proliferative, anti-inflammatory, and cardioprotective properties.
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产品名称 | diphenolase ↓ ↑ | monophenolase ↓ ↑ | tyrosinase ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hexylresorcinol |
+++
diphenolase, IC50: 0.85 μM |
++
monophenolase, IC50: 1.24 μM |
+++
monophenolase, IC50: 0.85 μM diphenolase, IC50: 0.85 μM |
99%+ | |||||||||||||||
Aloin | ✔ | 98% | |||||||||||||||||
Arbutin |
+
tyrosinase, IC50: 1.09 mM |
98% | |||||||||||||||||
Monobenzone | ✔ | 98% | |||||||||||||||||
Deoxyarbutin |
++++
tyrosinase, IC50: 50 nM |
98% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Oxyresveratrol(OXY), a stilbene extracted from C. mori root, its bioactivities include antioxidation, anti-inflammatory, neuroprotective, anti-viral, and tyrosinase-inhibitory activities[3]. Oxyresveratrol treatment of MDA-MB-231 cells showed the IC50 value at 48 h calculated from the MTT assay was 42 μM [4].OXY (10 μM) possesses an estrogenic activity and can induce proliferation of MCF-7 cells and upregulation of ERα/β expression [3].Oxyresveratrol ( 100 μM )dose-dependently inhibited lipid accumulation.The adipocyte markers of Pparγ and Fabp4 expressions were consistently suppressed by oxyresveratrol in the 3T3-L1 cells[5]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
4.09mL 0.82mL 0.41mL |
20.47mL 4.09mL 2.05mL |
40.94mL 8.19mL 4.09mL |
CAS号 | 29700-22-9 |
分子式 | C14H12O4 |
分子量 | 244.243 |
别名 | 氧化白黎芦醇 ;trans-Oxyresveratrol;trans-2',3,4',5-Tetramethoxystilbene |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Keep in dark place,Inert atmosphere,Room temperature |
溶解度 |
DMSO: 50 mg/mL(204.71 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |