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首页 / 生化试剂 / 脂类 / 脂肪酰类 / Methyl Stearate

十八碳酸甲酯 /Methyl Stearate {[allProObj[0].p_purity_real_show]}

货号：A171330 同义名： 硬脂酸甲酯 / Stearic acid methyl ester;Methyl octadecanoate

Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels.

Methyl Stearate 化学结构 CAS号：112-61-8
Methyl Stearate 化学结构
CAS号：112-61-8
Methyl Stearate 3D分子结构
CAS号：112-61-8
Methyl Stearate 化学结构 CAS号：112-61-8
Methyl Stearate 3D分子结构 CAS号：112-61-8
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Methyl Stearate 纯度/质量文件 产品仅供科研

货号：A171330 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

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Methyl Stearate 生物活性

描述 Stearic acid methyl ester (SAME) is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils. SAME can enhance MSCs (Mesenchymal stem cells) migration ability mainly through the Vav1/ROCK2 signaling pathway, which could contribute to the accelerated cartilage regeneration[1]. PAME (palmitic acid methyl ester), SAME, and Solutol HS15 provide robust neuroprotection in both paradigms of ischemia[2]. Stearic acid inhibited the colony-forming ability of 4 out of 5 rat and two human tumour continuous cell lines in vitro. Using a model of rat mammary carcinoma induced by nitroso-methyl urea (NMU) the subcutaneous injection of stearic acid at weekly intervals prevented tumour development in 5 to 10 rats. Stearic acid inhibits tumour development in rats[3]. Stearic acid significantly induced CD11c expression in monocytes through activation of the nuclear retinoid acid receptor[4].

Methyl Stearate 参考文献

[1]Liu Y, Xu L, Hu L, Chen D, Yu L, Li X, Chen H, Zhu J, Chen C, Luo Y, Wang B, Li G. Stearic acid methyl ester promotes migration of mesenchymal stem cells and accelerates cartilage defect repair. J Orthop Translat. 2019 Oct 23;22:81-91

[2]Lin HW, Saul I, Gresia VL, Neumann JT, Dave KR, Perez-Pinzon MA. Fatty acid methyl esters and Solutol HS 15 confer neuroprotection after focal and global cerebral ischemia. Transl Stroke Res. 2014 Feb;5(1):109-17

[3]Habib NA, Wood CB, Apostolov K, Barker W, Hershman MJ, Aslam M, Heinemann D, Fermor B, Williamson RC, Jenkins WE, et al. Stearic acid and carcinogenesis. Br J Cancer. 1987 Oct;56(4):455-8

[4]Zeng J, Zhang Y, Hao J, Sun Y, Liu S, Bernlohr DA, Sauter ER, Cleary MP, Suttles J, Li B. Stearic Acid Induces CD11c Expression in Proinflammatory Macrophages via Epidermal Fatty Acid Binding Protein. J Immunol. 2018 May 15;200(10):3407-3419

Methyl Stearate 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.35mL

0.67mL

0.34mL

16.75mL

3.35mL

1.68mL

33.50mL

6.70mL

3.35mL

Methyl Stearate 技术信息

CAS号112-61-8
分子式C19H38O2
分子量 298.504
别名 硬脂酸甲酯 ;Stearic acid methyl ester;Methyl octadecanoate;C18:0 Methyl ester
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月
溶解度

DMSO: 12 mg/mL(40.2 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方

Tags: Methyl Stearate | Stearic acid methyl ester;Methyl octadecanoate;C18:0 Methyl ester | 硬脂酸甲酯 | Aliphatic Acyl | AmBeed-信号通路专用抑制剂 | Methyl Stearate 纯度/质量文件 | Methyl Stearate 生物活性 | Methyl Stearate 参考文献 | Methyl Stearate 实验方案 | Methyl Stearate 技术信息

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