货号:A539125 同义名: 甲基倍他环糊精 / Methyl-beta-cyclodextrin;Randomly methylated β-cyclodextrin
Methyl-β-cyclodextrin是一种环状七糖,,易溶于水,形成稳定的水合物。对非极性物质有增溶作用,可以作为疏水性化合物的增溶剂。它还被广泛用作胆固醇消耗试剂,显著减少网格蛋白依赖性内吞作用并阻止细胞迁移体的形成。
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描述 | Methyl-β-cyclodextrin is a cyclic heptasaccharide utilized for delivering hydrophobic agents due to its property of dissolving nonpolar substances. It is also extensively used as a cholesterol-depleting agent[1]. Methyl-β-cyclodextrin possesses multiple biological activities. It significantly reduces clathrin-dependent endocytosis, thus serving as an endocytosis inhibitor[2]. Methyl-β-cyclodextrin inhibits cell migrasome formation[3]. Methyl-β-cyclodextrin is widely used to enhance cell permeability, thereby increasing the uptake of small molecules such as glucose and nanoparticles. In pharmaceutical formulations, Methyl-β-cyclodextrin is utilized to enhance the bioavailability of drugs[4]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
0.77mL 0.15mL 0.08mL |
3.84mL 0.77mL 0.38mL |
7.67mL 1.53mL 0.77mL |
CAS号 | 128446-36-6 |
分子式 | N/A |
分子量 | 1303.3 |
别名 | 甲基倍他环糊精 ;Methyl-beta-cyclodextrin;Randomly methylated β-cyclodextrin |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,Room Temperature |
溶解度 | |
动物实验配方 |