Fludrocortisone acetate is a synthetic mineralocorticoid, used to control the amount of sodium and fluids in your body. It is used to treat Addison's disease by decreasing the amount of sodium that is lost (excreted) in your urine, also used to increase blood pressure. Treatment with FCA (Fludrocortisone Acetate) produced dose-dependent (5, 10, and 25 mg/kg) increases in both magnitude and duration of water and sodium intake. Chronic elevation of water and saline intake was achieved with daily injections of FCA. Daily injection of FCA, when only 0.9% saline was available, produced a remarkably rapid increase in saline intake. A single injection of FCA stimulated brisk diuresis and natriuresis in fluid-restricted animals[3]. Administration of fludrocortisone resulted in a significant decrease in the UACR (urinary aldosterone to creatinine ratio) in healthy cats. Using the UACR for an oral fludrocortisone suppression test may be useful for the diagnosis of primary hyperaldosteronism in cats[4]. DOCP (desoxycorticosterone pivalate) treatment more effectively suppresses PRA (plasma renin activity) compared to FC (fludrocortisone acetate) in dogs with PH (primary hypoadrenocorticism) [5].
United States, Arizona
... 展开 >>
Mayo Clinic Arizona
Scottsdale, Arizona, United States, 85259
United States, California
City Of Hope
Duarte, California, United States, 91010-3000
The Angeles Clinic & Research Institute
Los Angeles, California, United States, 90025
United States, Connecticut
Yale University School Of Medicine
New Haven, Connecticut, United States, 06520
United States, Illinois
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Oncology Specialists, S.C.
Park Ridge, Illinois, United States, 60068
United States, Indiana
Indiana University Cancer Center
Indianapolis, Indiana, United States, 46202
United States, Massachusetts
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
United States, New Hampshire
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
United States, New York
Local Institution
Bronx, New York, United States, 10466
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
United States, Oregon
Providence Portland Med Ctr
Portland, Oregon, United States, 97213
United States, Tennessee
Vanderbilt-Ingram Cancer Ctr
Nashville, Tennessee, United States, 37232
United States, Washington
Seattle Cancer Care Alliance
Seattle, Washington, United States, 98109-1023 收起 <<
United States, New York
... 展开 >>
VA Medical Center, Bronx
Not yet recruiting
Bronx, New York, United States, 10468
Contact: Jill Wecht, EdD jm.wecht@va.gov
Contact: Nhuquynh Nguyen, BS 718-584-9000 ext 1732 Nhuquyhn.nguyen@va.gov
Principal Investigator: Jill Wecht, EdD
Sub-Investigator: William Bauman, MD
Mount Sinai School of Medicine
Recruiting
New York, New York, United States, 10029
Contact: Andrew Delgado, MS
Contact: Kristall Taylor, BS
Principal Investigator: Thomas Bryce, MD
Sub-Investigator: Miguel Escalon, MD 收起 <<
United States, North Carolina
... 展开 >>
Wake Forest Baptist Health
Recruiting
Winston-Salem, North Carolina, United States, 27157
Contact: Anya Brown 336-716-4325 anybrown@wakehealth.edu
Contact: Hossam Shaltout, PhD 收起 <<
United States, California
... 展开 >>
Children's Hospital of Los Angeles
Not yet recruiting
Los Angeles, California, United States, 90027
Contact: Mitchell Geffner, MD mgeffner@chla.usc.edu
United States, Maryland
National Institutes of Health
Not yet recruiting
Bethesda, Maryland, United States, 20892-1932
Contact: Deborah Merke, MD 301-496-0718 DMerke@cc.nih.gov
United States, Michigan
University of Michigan
Not yet recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Richard Auchus, MD rauchus@med.umich.edu
United States, New York
North Shore/Long Island Jewish Hospital
Not yet recruiting
New Hyde Park, New York, United States, 11040
Contact: Phyllis W Speiser, MD 516-472-3750 mailto:PSpeiser@northwell.edu
United States, Texas
Children's Medical Center
Recruiting
Dallas, Texas, United States, 75235
Contact: Carolyn Kelly, RN, BS 214-456-2106 carolyn.kelly@childrens.com 收起 <<
United States, California
... 展开 >>
Children's Hospital of Los Angeles
Not yet recruiting
Los Angeles, California, United States, 90027
Contact: Mitchell Geffner, MD
United States, Maryland
National Institutes of Health
Not yet recruiting
Bethesda, Maryland, United States, 20892
Contact: Deborah Merke
United States, Michigan
University of Michigan
Ann Arbor, Michigan, United States, 48109
United States, New York
North Shore/Long Island Jewish Hospital
New Hyde Park, New York, United States, 11040
United States, Texas
Children's Medical Center
Dallas, Texas, United States, 75235 收起 <<
France
... 展开 >> Henri Mondor Hospital
Créteil, France, 94
Raymond Poincaré Hospital
Garches, France, 92380
Pitié Salpêtrière Hospital
Paris, France, 75
Saint Josef Hospital
Paris, France, 75 收起 <<
United States, Massachusetts
... 展开 >>
Brigham and Women's Hospital
Recruiting
Boston, Massachusetts, United States, 02115
Principal Investigator: Jonathan S Williams, MD, MMSc
Sub-Investigator: Gordon Williams, MD
Sub-Investigator: Tina Gupta, MD 收起 <<
France
... 展开 >> Hôpital Avicenne
Bobigny, France
Hôpital Jean Verdier
Bondy, France
CHU Grenoble
Grenoble, France
Hôpital central
Nancy, France
Hôpital Saint Louis
Paris, France, 75
Hôpital Bichat Claude Bernard
Paris, France
hôpital Cochin
Paris, France
Hôpital Delafontaine
Saint Denis, France, 93 收起 <<
United States, Georgia
... 展开 >>
Emory University
Atlanta, Georgia, United States, 30322
United States, North Carolina
University of North Carolina
Chapel Hill, North Carolina, United States, 27599 收起 <<
Germany
... 展开 >> Charité Universitätsmedizin Berlin
Recruiting
Berlin, Germany, 12203
Contact: Christian Otte, Prof. Dr. +49-30-450-517532 Christian.Otte@charite.de 收起 <<
France
... 展开 >> University hospital
Amiens, France
University Hospital
Angers, France
University Hospital
Beaujon, France
University hospital
Bordeaux, France, 33000
University Hospital
Brest, France
Universtiy Hospital
Caen, France
University Hospital
Clermont Ferrand, France
University hospital
Creteil, France, 94000
University Hospital
Creteil, France
University Hospital
Grenoble, France
University Hospital
Montpellier, France
University Hospital
Nantes, France
University Hospital
Nimes, France
European Hospital Georges Pompidou
Paris, France, 75000
Saint Louis Hospital
Paris, France, 75000
University hospital
Poitiers, France, 86000
University Hospital
Strasbourg, France
University Hospital
Toulouse, France 收起 <<
United States, Massachusetts
... 展开 >>
Boston University
Boston, Massachusetts, United States, 02118
United States, Tennessee
Vanderbilt University
Nashville, Tennessee, United States, 37232-2195
United States, Virginia
Virginia Cardiovascular Specialists
Richmond, Virginia, United States, 23225-3838
Canada, Alberta
University of Calgary, Faculty of Medicine
Calgary, Alberta, Canada, T2N 4N1
Alberta Children's Hospital
Calgary, Alberta, Canada, T3B 6A8
Canada, Manitoba
St. Boniface General Hospital
Winnipeg, Manitoba, Canada, R2H 2A6
Canada, Nova Scotia
Queen Elizabeth II, Halifax Infirmary
Halifax, Nova Scotia, Canada, B3H 3A7
Canada, Ontario
McMaster University, Hamilton Health Sciences
Hamilton, Ontario, Canada, L8L 2X2
Queen's University
Kingston, Ontario, Canada, K7V 2V7
University of Western Ontario, London Health Sciences
London, Ontario, Canada, N6A 5A5
University of Ottawa, Ottawa Heart Institute
Ottawa, Ontario, Canada, K1Y 4W7
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8
Canada, Quebec
Institut de Cardiologie de Montreal
Montreal, Quebec, Canada, H1T 1C8
Hopital Sacre Coeur de Montreal
Montreal, Quebec, Canada, H4J 1C5 收起 <<
Brazil
... 展开 >> General Hospital of School of Medicine - Universiy of Sao Paulo
Recruiting
Sao Paulo, SP, Brazil, 05403-000
Contact: Andrea P Abreu, MD (5511) 86921219 andreapioabreu@gmail.com
Contact: Decio Mion Junior, MD, PhD (5511) 26617686 deciomion@uol.com.br
Sub-Investigator: Andrea P Abreu, MD
Principal Investigator: Decio Mion Junior, MD, PhD 收起 <<
United States, Oregon
... 展开 >>
Oregon Health & Science University
Recruiting
Portland, Oregon, United States, 97239
Contact: Anh Nguyen-Huynh 503-260-9192 nguyanh@ohsu.edu
Principal Investigator: Anh Nguyen-Huynh, MD PhD 收起 <<
搜索
