货号:A1152213 同义名: ARRY-520 hydrochloride
Filanesib hydrochloride是一种 Kinesin spindle protein (KSP) 抑制剂,能够干扰细胞分裂。它在癌症治疗中展现出显著的抗增生活性。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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产品名称 | Kinesin ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SB-743921 HCl |
++++
KSP, Ki: 0.07 nM KSP (P388 cells), IC50: 14.4 nM |
99%+ | |||||||||||||||||
GSK-923295 |
++
CENP-E, Ki: 3.2 nM |
99%+ | |||||||||||||||||
Ispinesib |
+++
KSP (HsEg5), Ki app: 1.7 nM |
99%+ | |||||||||||||||||
AZ3146 |
+
Mps1, IC50: ~35 nM |
98+% | |||||||||||||||||
MPI-0479605 |
++
Mps1, IC50: 1.8 nM |
99%+ | |||||||||||||||||
BAY1217389 |
+++
Mps1, IC50: 0.63 nM |
98% | |||||||||||||||||
ARQ 621 | ✔ | 98% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
产品名称 | c-Kit ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrphostin AG1296 |
+
c-Kit (Swiss 3T3), IC50: 1.8 μM |
PDGFR | 99%+ | ||||||||||||||||
Masitinib |
+
Kit, IC50: 200 nM |
99%+ | |||||||||||||||||
Motesanib Diphosphate |
+++
Kit, IC50: 8 nM |
98% | |||||||||||||||||
Ki8751 |
++
c-Kit, IC50: 40 nM |
98+% | |||||||||||||||||
Tivozanib |
++
c-Kit, IC50: 78 nM |
99%+ | |||||||||||||||||
Pazopanib |
+
c-Kit, IC50: 140 nM |
99% | |||||||||||||||||
Sitravatinib |
+++
Kit, IC50: 6 nM |
99%+ | |||||||||||||||||
Pexidartinib |
+++
Kit, IC50: 10 nM |
99%+ | |||||||||||||||||
Lactate |
++++
c-Kit, IC50: 2 nM |
FLT3 | 85% | ||||||||||||||||
Amuvatinib |
+++
c-Kit (D816H), IC50: 10 nM |
99%+ | |||||||||||||||||
Imatinib Mesylate |
+
c-Kit, IC50: 100 nM |
PDGFR | 99% | ||||||||||||||||
AZD2932 |
+++
c-Kit, IC50: 9 nM |
98% | |||||||||||||||||
Axitinib |
++++
Kit, IC50: 1.7 nM |
98% | |||||||||||||||||
Dovitinib |
++++
c-Kit, IC50: 2 nM |
FLT3 | 99%+ | ||||||||||||||||
Sunitinib | ✔ | FLT3 | 98% | ||||||||||||||||
OSI-930 |
+
Kit, IC50: 80 nM |
99%+ | |||||||||||||||||
Telatinib |
++++
c-Kit, IC50: 1 nM |
99%+ | |||||||||||||||||
Dasatinib monohydrate |
++
c-Kit (D816V), IC50: 37 nM c-Kit (wt), IC50: 79 nM |
Src | 98% | ||||||||||||||||
Dasatinib |
++
c-Kit (wt), IC50: 79 nM c-Kit (D816V), IC50: 37 nM |
Src | 98% | ||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.19mL 0.44mL 0.22mL |
10.94mL 2.19mL 1.09mL |
21.88mL 4.38mL 2.19mL |
CAS号 | 1385020-40-5 |
分子式 | C20H23ClF2N4O2S |
分子量 | 456.937 |
别名 | ARRY-520 hydrochloride |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,2-8°C |
溶解度 | |
动物实验配方 |