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产品名称 | PD-1 ↓ ↑ | PD-1/PD-L1 ↓ ↑ | PD-1/PD-L1 interaction ↓ ↑ | PD-L1 ↓ ↑ | 其他靶点 | 纯度 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SR0987 | ✔ | 98% | |||||||||||||||||
Pembrolizumab | ✔ | 98% | |||||||||||||||||
Camrelizumab | ✔ | 5mg/mL | |||||||||||||||||
Spartalizumab | ✔ | 95% | |||||||||||||||||
BMS-1001 |
+
PD-1/PD-L1, EC50: 253 nM |
+
PD-1/PD-L1, EC50: 253 nM |
98% | ||||||||||||||||
INCB086550 |
++
PD-1/PD-L1, IC50: <10 nM |
++
PD-1/PD-L1, IC50: <10 nM |
98% | ||||||||||||||||
BMS-1 |
++
PD-1/PD-L1 interaction, IC50: 0.006 μM |
99%+ | |||||||||||||||||
BMS-202 |
+
PD-1/PD-L1 interaction, IC50: 0.018 μM |
99%+ | |||||||||||||||||
PD-1/PD-L1-IN 3 |
+++
PD-1/PD-L1 interaction, IC50: 5.6 nM |
98+% | |||||||||||||||||
Nivolumab |
+++
PD-1/PD-L1 interaction, IC50: 2.52 nM |
95% | |||||||||||||||||
BMS-1166 |
+++
PD-1/PD-L1 interaction, IC50: 1.4 nM |
99%+ | |||||||||||||||||
Durvalumab |
++++
PD-1/PD-L1 interaction, IC50: 0.1 nM |
95% | |||||||||||||||||
Evixapodlin |
++++
PD-1/PD-L1, IC50: 0.213 nM |
95% | |||||||||||||||||
CA-170 | ✔ | 97% (contains 2.7% ethanol) | |||||||||||||||||
Atezolizumab |
+++
hPD-L1, Kd: 0.4 nM |
98% | |||||||||||||||||
AUNP-12 | ✔ | 99% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Product Name: Feladilimab Corss-reactivity: Human,Cynomolgus Organism:Human Target name: ICOS / CD278 Recommended Dilution Buffer: Sterile PBS or 0.9% saline for reconstitution/dilution. It is recommended to use the reconstituted/diluted product within one month. Formulation: 100 mM Pro-Ac,20 mM Arg,pH5.0 Endotoxin: < 0.001EU/μg, determined by LAL method. Purity: >95%. Determined by SDS-PAGE Purification: Purified, Protein A, affinity column Storage: -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles. Isotype: IgG4PE-Kappa |
CAS号 | 2252518-85-5 |
分子式 | |
分子量 |
别名 | Anti-ICOS/CD278 Reference Antibody (feladilimab);GSK3359609 |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 |
溶解度 | |
动物实验配方 |