There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
---|---|---|---|---|---|---|---|
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{[ getRatePrice(item.pr_rmb, 1,1) ]} | {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} | 现货 | 咨询 | - + |
快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | Factor Xa ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rivaroxaban |
++
Factor Xa, IC50: 0.7 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Apixaban |
++++
Factor Xa (rabbit), Ki: 0.17 nM Factor Xa (human), Ki: 0.08 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Edoxaban tosylate monohydrate |
+++
Factor Xa, Ki: 0.561 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
靶点 |
|
描述 | Edoxaban tosylate monohydrate is an orally active, potent, selective and direct FXa inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and thrombin, and is more than 10,000-fold selective for free human FXa and thrombomodulin over other thrombin enzymes.Edoxaban tosylate monohydrate is used in thromboembolic disease prevention studies. Edoxaban tosylate monohydrate is used in studies for the prevention of thromboembolic diseases.Edoxaban tosylate monohydrate prolongs human plasma PT, TT, and APTT in a concentration-dependent manner[1]. |
Animal study | Administered as a single oral dose at 0.5, 2.5 and 12.5 mg/kg, Edoxaban tosylate monohydrate inhibited exogenous FXa activity, significantly and dose-dependently reducing thrombosis and prolonging PT in a venous stasis thrombosis model in Wistar rats and male New Zealand White rabbits[1]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.35mL 0.27mL 0.14mL |
6.77mL 1.35mL 0.68mL |
13.55mL 2.71mL 1.35mL |
CAS号 | 1229194-11-9 |
分子式 | C31H40ClN7O8S2 |
分子量 | 738.274 |
别名 | DU-176b monohydrate;DU-176b |
运输 | 蓝冰 |
存储条件 |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 50 mg/mL(67.73 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 1 mg/mL(1.35 mM),配合低频超声助溶 |
动物实验配方 |