Apixaban | BMS-562247-01 | Factor Xa | AmBeed-信号通路专用抑制剂

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

规格	价格	会员价	库存	数量
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产品名称	Factor Xa ↓ ↑	纯度
Rivaroxaban	++ Factor Xa, IC50: 0.7 nM	98%
Apixaban	++++ Factor Xa (rabbit), Ki: 0.17 nM Factor Xa (human), Ki: 0.08 nM	98%
Edoxaban tosylate monohydrate	+++ Factor Xa, Ki: 0.561 nM	98+%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02492828	-		Completed	-	-
NCT01780987	Deep Vein Thrombosis ... 展开 >> Pulmonary Embolism 收起 <<	Phase 3	Completed	-	Japan ... 展开 >> Aichi Medical University Hospital Nagakute, Aichi, Japan, 480-1195 Toho University Sakura Medical Center Sakura, Chiba, Japan, 285-8741 Kokura Memorial Hospital Kitakyusyu, Fukuoka, Japan, 802-8555 Hiroshima General Hospital Hatsukaichi, Hiroshima, Japan, 738-8503 Teine Keijinkai Hospital Sapporo, Hokkaido, Japan, 006-8555 Kanazawa Medical University Hospital Kahoku-gun, Ishikawa, Japan, 920-0293 Yokohama Minami Kyousai Hospital Yokohama, Kanagawa, Japan, 236-0037 National Hospital Organization Yokohama Medical Center Yokohama, Kanagawa, Japan, 245-8575 Mie University Hospital Tsu, MIE, Japan, 514-8507 National Hospital Organization Okayama Medical Center Okayama City, Okayama, Japan, 701-1192 Kinki University Hospital Osakasayama, Osaka, Japan, 589-8511 National Cerebral and Cardiovascular Center Hospital Suita-shi, Osaka, Japan, 565-8565 St. Luke's International Hospital Chuo-ku, Tokyo, Japan, 104-8560 Nihon University Itabashi Hospital Itabashi-ku, Tokyo, Japan, 173-8610 National Hospital Organization Tokyo Medical Center Meguro-ku, Tokyo, Japan, 152-8902 Japanese Red Cross Musashino Hospital Musashino, Tokyo, Japan, 180-8610 Tokyo Medical University Hospital Shinjuku-ku, Tokyo, Japan, 160-0023 Fukushima Medical University Hospital Fukushima, Japan, 960-1295 Kumamoto University Hospital Kumamoto, Japan, 860-8556 Saiseikai Kumamoto Hospital Kumamoto, Japan, 861-4193 收起 <<
NCT02640222	-		Active, not recruiting	December 31, 2019	-
NCT03398434	Atrial Fibrillation	Phase 2	Withdrawn(Study Cancelled befo... 展开 >>re FPFV (no patient enrolled)) 收起 <<	January 30, 2020	-
NCT02942407	Atrial Fibrillation ... 展开 >> End Stage Renal Disease 收起 <<	Phase 4	Recruiting	September 2019	-
NCT02789917	Acute Coronary Syndrome ... 展开 >> Atrial Fibrillation Coronary Artery Disease 收起 <<	Phase 4	Recruiting	December 2018	Germany ... 展开 >> Munich University Hospital Recruiting Munich, Bavaria, Germany, 81377 Contact: Reza Wakili, MD +49894400 ext 73036 reza.wakili@med.uni-muenchen.de Contact: Lisa Maria Riesinger, MD +49894400 ext 0 Lisa_Maria.Riesinger@med.uni-muenchen.de Universitätsklinikum der RWTH Aachen Recruiting Aachen, Germany Charité, Campus Virchow-Klinikum Recruiting Berlin, Germany Klinikum Coburg Recruiting Coburg, Germany Westdeutsches Herzzentrum am Universitätsklinikum Recruiting Essen, Germany Universitätsmedizin Greifswald Recruiting Greifswald, Germany Universitätsmedizin Göttingen Not yet recruiting Göttingen, Germany Universitätsklinikum Heidelberg Recruiting Heidelberg, Germany UKHS Campus Kiel Recruiting Kiel, Germany Klinikum Lüdenscheid Not yet recruiting Lüdenscheid, Germany Universitätsmedizin Mainz Recruiting Mainz, Germany Klinikum Augustinum Recruiting München, Germany Städtisches Klinikum München-Neuperlach Not yet recruiting München, Germany Universitätsmedizin Rostock Recruiting Rostock, Germany 收起 <<
NCT01780987	-		Completed	-	-
NCT02080858	Atrial Fibrillation ... 展开 >> Acute Coronary Syndrome 收起 <<	Phase 1	Completed	-	Austria ... 展开 >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 收起 <<
NCT02818868	-		Not yet recruiting	May 2019	-
NCT00852397	Acute Coronary Syndrome	Phase 2	Terminated(See termination rea... 展开 >>son in detailed description.) 收起 <<	-	Japan ... 展开 >> Pfizer Investigational Site Kasuga, Fukuoka, Japan Pfizer Investigational Site Kitakyusyu, Fukuoka, Japan Pfizer Investigational Site Kure, Hiroshima, Japan Pfizer Investigational Site Sapporo, Hokkaido, Japan Pfizer Investigational Site Uji, Kyoto, Japan Pfizer Investigational Site Ikoma, Nara, Japan Pfizer Investigational Site Hirakata, Osaka, Japan Pfizer Investigational Site Kawachinagano, Osaka, Japan Pfizer Investigational Site Matsubara, Osaka, Japan Pfizer Investigational Site Yao, Osaka, Japan Pfizer Investigational Site Wako, Saitama, Japan Pfizer Investigational Site Sunto, Shizuoka, Japan Pfizer Investigational Site Minato-Ku, Tokyo, Japan Pfizer Investigational Site Shinagawa, Tokyo, Japan Pfizer Investigational Site Gifu, Japan Pfizer Investigational Site Hiroshima, Japan Pfizer Investigational Site Kumamoto, Japan Pfizer Investigational Site Osaka, Japan 收起 <<
NCT00412984	-		Completed	-	-
NCT02339818	-		Completed	-	United States, New Jersey ... 展开 >> Local Institution Princeton, New Jersey, United States, 08540 收起 <<
NCT00852397	-		Terminated(See termination rea... 展开 >>son in detailed description.) 收起 <<	-	-
NCT00787150	Atrial Fibrillation	Phase 2	Completed	-	Japan ... 展开 >> Pfizer Investigational Site Nagoya, Aichi, Japan Pfizer Investigational Site Seto, Aichi, Japan Pfizer Investigational Site Touon, Ehime, Japan Pfizer Investigational Site Kitakyushu, Fukuoka, Japan Pfizer Investigational Site Ogaki, Gifu, Japan Pfizer Investigational Site Isezaki, Gunma, Japan Pfizer Investigational Site Shibukawa, Gunma, Japan Pfizer Investigational Site Sapporo, Hokkaido, Japan Pfizer Investigational Site Higashiibaraki-gunn Ibarakimachi, Ibaraki, Japan Pfizer Investigational Site Zentsuji, Kagawa, Japan Pfizer Investigational Site Kawasaki, Kanagawa, Japan Pfizer Investigational Site Tsu, Mie, Japan Pfizer Investigational Site Minato-ku, Tokyo, Japan Pfizer Investigational Site Shinagawa-ku, Tokyo, Japan Pfizer Investigational Site Shinjuku-ku, Tokyo, Japan Pfizer Investigational Site Iwakuni, Yamaguchi, Japan Pfizer Investigational Site Fukuoka, Japan Pfizer Investigational Site Kumamoto, Japan 收起 <<
NCT03100071	-		Recruiting	December 31, 2019	Canada, Ontario ... 展开 >> London Health Science Center, Victoria Hospital Recruiting London, Ontario, Canada, N6A 5W9 Contact 519-685-8500 收起 <<
NCT00412984	Atrial Fibrillation ... 展开 >> Atrial Flutter 收起 <<	Phase 3	Completed	-	-
NCT00787150	-		Completed	-	-
NCT00320255	Thrombosis Ca... 展开 >>ncer Pulmonary Embolism 收起 <<	Phase 2	Completed	-	United States, Arizona ... 展开 >> Arizona Cancer Center Tucson, Arizona, United States, 85724 United States, California Univ. Of Southern Calif. /Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 United States, Massachusetts Dana-Farber Cancer Inst Boston, Massachusetts, United States, 02115 United States, Nevada Nevada Cancer Institute Las Vegas, Nevada, United States, 89135 United States, New York Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Mount Sinai School Of Medicine New York, New York, United States, 10029 University Of Rochester Rochester, New York, United States, 14642 United States, Texas University Of Texas Md Anderson Cancer Ctr Houston, Texas, United States, 77030 Canada, Ontario Local Institution Hamilton, Ontario, Canada, L8V 2C5 Local Institution London, Ontario, Canada, N6A 4L6 Local Institution Toronto, Ontario, Canada, M4N 3M5 Local Institution Toronto, Ontario, Canada, M5G 2M9 Canada, Quebec Local Institution Montreal, Quebec, Canada, H1T 2M4 Local Institution Montreal, Quebec, Canada, H3G 1A4 收起 <<
NCT00320255	-		Completed	-	-
NCT00633893	Venous Thrombosis	Phase 3	Completed	-	-
NCT02100228	Atrial Fibrillation	Phase 4	Completed	-	-
NCT02100228	-		Completed	-	-
NCT00643201	Venous Thrombosis	Phase 3	Completed	-	-
NCT00633893	-		Completed	-	-
NCT02007655	-		Active, not recruiting	December 31, 2020	Japan ... 展开 >> Local Institution Toyama-shi, Toyama, Japan, 930-0194 收起 <<
NCT03026556	-		Completed	-	United States, New Jersey ... 展开 >> Inventiv Health Princeton, New Jersey, United States, 08450 收起 <<
NCT00643201	-		Completed	-	-
NCT00313300	Acute Coronary Syndrome (ACS)	Phase 2	Completed	-	-
NCT01437839	Healthy	Phase 1	Completed	-	Singapore ... 展开 >> Pfizer Investigational Site Singapore, Singapore, 188770 收起 <<
NCT02270918	Thrombosis	Phase 1	Completed	-	United States, Pennsylvania ... 展开 >> Thomas Jefferson University Hosptial Philadelphia, Pennsylvania, United States, 19107 收起 <<
NCT01885585	-		Completed	-	Korea, Republic of ... 展开 >> Local Institution Seoul, Korea, Republic of, 110-744 收起 <<
NCT02565693	Cerebral Hemorrhage ... 展开 >> Atrial Fibrillation 收起 <<	Phase 2	Recruiting	January 31, 2021	Netherlands ... 展开 >> Amsterdam UMC Recruiting Amsterdam, Netherlands Principal Investigator: Jonathan Coutinho, MD PhD OLVG Recruiting Amsterdam, Netherlands Principal Investigator: Vincent IH Kwa, MD PhD Gelre Ziekenhuizen Recruiting Apeldoorn, Netherlands Principal Investigator: Henri P Bienfait, MD Rijnstate Recruiting Arnhem, Netherlands Principal Investigator: Jeannette Hofmeijer, MD PhD Amphia Ziekenhuis Recruiting Breda, Netherlands Principal Investigator: Michel JM Remmers, MD Haaglanden MC Recruiting Den Haag, Netherlands Contact: Ido R van den Wijngaard +31 88 979 2508 i.van.den.wijngaard@haaglandenmc.nl Albert Schweitzer Ziekenhuis Recruiting Dordrecht, Netherlands Principal Investigator: Henk Kerkhoff, MD PhD Medisch Spectrum Twente Recruiting Enschede, Netherlands Principal Investigator: Heleen M den Hertog, MD PhD University Medical Center Groningen Recruiting Groningen, Netherlands Principal Investigator: Gert-Jan Luijckx, MD PhD Zuyderland Ziekenhuis Recruiting Heerlen, Netherlands Principal Investigator: Antonia CH Schreuder, MD Leiden University Medical Center Recruiting Leiden, Netherlands Principal Investigator: Marieke JH Wermer, MD PhD Maastricht University Medical Center Recruiting Maastricht, Netherlands Principal Investigator: Julie Staals, MD PhD Radboud University Medical Center Recruiting Nijmegen, Netherlands Principal Investigator: Catherina JM Klijn, MD PhD Erasmus MC Recruiting Rotterdam, Netherlands Principal Investigator: Diederik WJ Dippel, MD PhD Elisabeth-Tweesteden Ziekenhuis Recruiting Tilburg, Netherlands Principal Investigator: Julia H van Tuijl, MD PhD UMC Utrecht Recruiting Utrecht, Netherlands, 3584CX Contact: Bart M van der Worp, MD, PhD +31887577975 h.b.vanderworp@umcutrecht.nl Principal Investigator: H Bart van der Worp, MD PhD Sub-Investigator: Koen M van Nieuwenhuizen, MD 收起 <<
NCT02369653	Lymphoma Acut... 展开 >>e Lymphoblastic Leukemia 收起 <<	Phase 3	Recruiting	May 28, 2020	-
NCT00313300	-		Completed	-	-
NCT00914641	Thrombosis	Phase 1	Completed	-	United States, Connecticut ... 展开 >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 收起 <<
NCT02666157	Atrial Fibrillation	Phase 4	Unknown	December 2018	Taiwan ... 展开 >> National Cheng Kung University Hospital Recruiting Tainan, Tainan City, Taiwan, 704 Contact: Ting-Hsing Chao, MD 886-6-2353535 ext 2382 chaoth@mail.ncku.edu.tw Principal Investigator: Ting-Hsing Chao, MD Sub-Investigator: Ju-Yi Chen, MD and PhD Sub-Investigator: Cheng-Han Lee, MD and PhD Sub-Investigator: Chih-Chan Lin, MD Sub-Investigator: Chih-Hung Chen, MD Sub-Investigator: Liang-Miin Tsai, MD Sub-Investigator: Li-Jen Lin, MD Sub-Investigator: Wei-Chuan Tsai, MD Sub-Investigator: Ping-Yen Liu, MD and PhD Tainan Hospital Ministry of Health and Welfare Not yet recruiting Tainan, Tainan City, Taiwan, 704 Contact: Li-Dan Yang, MD 886-6-2200055 ext 9 litannyang@yahoo.com.tw Principal Investigator: Li-Dan Yang, MD National Cheng Kung University Hospital Dou-Liou Branch Not yet recruiting Dou-Liou City, Taiwan, 640 Contact: Yang-Cheh Hsueh, MD 886-5-5332121 ext 5101 p308378@dou6.hosp.ncku.edu.tw Principal Investigator: Yang-Cheh Hsueh, MD Sub-Investigator: Yuen-Ting Sung, MD and PhD E-DA Hospital Not yet recruiting Kaohsiung, Taiwan, 824 Contact: Wei-Kung Tseng, MD and PhD 886-7-6150011 ext 5005 arthurtseng@me.com Principal Investigator: Wei-Kung Tseng, MD and PhD Tainan Municipal Hospital Recruiting Tainan, Taiwan, 701 Contact: I-Chih Chen, MD 886-6-2609926 ext 212045 ichih1230@yahoo.com.tw Principal Investigator: I-Chih Chen, MD Sub-Investigator: Ruei-Chang Zeng, MD 收起 <<
NCT02227550	Atrial Fibrillation	Phase 4	Completed	-	United States, New York ... 展开 >> Montefiore Medical Center New York, New York, United States United States, Pennsylvania Hospital of the University of Pennsyvlania Philadelphia, Pennsylvania, United States United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States United States, Texas Texas Cardiac Arrhythmia Research Austin, Texas, United States United States, Virginia Sentara Cariovascular Research Insititute Norfolk, Virginia, United States Austria 4 Sites Different, Austria Belgium 5 Sites Different, Belgium Denmark 5 Sites Different, Denmark Germany 13 Sites Different, Germany Italy 4 Sites Different, Italy Netherlands 6 Sites Different, Netherlands Spain 3 Sites Different, Spain United Kingdom 4 Sites Different, United Kingdom 收起 <<
NCT02066454	Myeloma Venou... 展开 >>s Thromboembolism 收起 <<	Phase 3	Unknown	July 2017	France ... 展开 >> CHRA Recruiting Annecy, France, 74374 Contact: Frédérique ORSINI, MD 04 50 63 66 08 Principal Investigator: Frédérique ORSINI, MD Sub-Investigator: Pascale CONY-MAKHOUL, MD Sub-Investigator: Anne PARRY, MD Sub-Investigator: Bernadette CORRONT, MD Sub-Investigator: DAGUINDAU Nicolas, MD Ch La Cote Basque Recruiting Bayonne, France, 64100 Contact: Anne BANOS, MD 05 59 44 38 32 abanos@ch-cotebasque.fr Principal Investigator: Anne BANOS, MD Sub-Investigator: Carla ARAUJO, MD Hia Percy Recruiting Clamart, France, 92141 Contact: Thierry DE REVEL, MD 01 41 46 63 01 thderevel@gmail.com Principal Investigator: Thierry DE REVEL, MD Chu Hopital Henri Mondor Recruiting Creteil, France, 94010 Contact: Karim BELHADJ-MERZOUG, MD 01 49 81 49 63 karim.belhadj@hmn.aphp.fr Principal Investigator: Karim BELHADJ-MERZOUG, MD Centre Hospitalier Recruiting Dunkerque, France, 59385 Contact: Marc WETTERWALD, MD 03 28 28 56 33 marc.wetterwald@ch-dunkerque.fr Principal Investigator: Marc WETTERWALD, MD Chu Grenoble Recruiting Grenoble, France, 38043 Contact: Brigitte PEGOURIE, MD 04 76 76 55 90 bpegourie@chu-grenoble.fr Principal Investigator: Brigitte PEGOURIE, MD Sub-Investigator: Rémy GRESSIN, MD Sub-Investigator: Lysiane MOLINA, MD Sub-Investigator: Audrey SIMON, MD Sub-Investigator: Stéphane COURBY, MD Sub-Investigator: Claude-Eric BULABOIS, MD Sub-Investigator: Anne THIEBAUT, MD Sub-Investigator: Jean-Yves CAHN, PHD Chd Vendee Recruiting La Roche Sur Yon, France, 85925 Contact: Mourad TIAB, MD 02 51 44 61 73 mourad.tiab@chd-vendee.fr Principal Investigator: Mourad TIAB, MD Clinique Victor Hugo Recruiting Le Mans, France, 72000 Contact: Eric VOOG, MD Principal Investigator: Eric VOOG, MD Hopital St Vincent - Ghicl Recruiting Lille, France, 59020 Contact: Manuel CLIQUENNOIS, MD 03 20 87 45 32 cliquennois.manuel@ghicl.net Principal Investigator: Manuel CLIQUENNOIS, MD Chru Hopital Huriez Recruiting Lille, France, 59037 Contact: Thierry FACON, MD 03 20 44 57 12 thierry.facon@chru-lille.fr Principal Investigator: Thierry FACON, MD Sub-Investigator: Xavier LELEU, MD Centre Leon Berard Recruiting Lyon, France, 69373 Contact: Philippe REY, MD 04 78 78 67 95 philippe.rey@lyon.unicancer.fr Principal Investigator: Philippe REY, MD Sub-Investigator: Catherine SEBAN, MD Sub-Investigator: Pierre BIRON, MD Groupe Hospitalier Du Havre Recruiting Montivilliers, France, 76290 Contact: Charles ZARNITSKY, MD 02 32 73 33 78 charles.zarnitsky@ch-havre.fr Principal Investigator: Charles ZARNITSKY, MD Hopital de L'Archet Recruiting Nice, France, 06202 Contact: Jean-Gabriel FUZIBET, MD 04 92 03 58 23 fuzibet.jg@chu-nice.fr Principal Investigator: Jean-Gabriel FUZIBET, MD Hopital Pitie Salpetriere Recruiting Paris, France, 75651 Contact: Damien ROOS-WEIL, MD 01 42 16 28 34 damienroosweil@voila.fr Principal Investigator: Damien ROOS-WEIL, MD Sub-Investigator: Véronique MOREL-MALEK, MD Ch de Perigueux Recruiting Perigueux, France, 24000 Contact: Philippe RODON, MD 05 53 45 29 78 rodon.philippe@wanadoo.fr Principal Investigator: Philippe RODON, MD Chu Bordeaux Recruiting Pessac, France, 33604 Contact: Gérald MARIT, MD 05 57 65 65 11 gerald.marit@chu-bordeaux.fr Principal Investigator: Gérald MARIT, MD Sub-Investigator: Axelle LASCAUX, MD Sub-Investigator: Sophie DIMICOLI-SALAZAR, MD Ch Lyon Sud Recruiting Pierre Benite, France, 69310 Contact: Lionel KARLIN, MD 04 78 86 43 09 lionel.karlin@chu-lyon.fr Principal Investigator: Lionel KARLIN, MD Chu Poitiers Recruiting Poitiers, France, 86021 Contact: Isabelle AZAIS, MD 05 49 44 44 65 i.azais@chu-poitiers.fr Principal Investigator: Isabelle AZAIS, MD Chru de Tours Recruiting Tours, France, 37000 Contact: Lotfi BENBOUKER, MD Principal Investigator: Lotfi BENBOUKER, MD 收起 <<
NCT01924325	Ischemic Stroke ... 展开 >> TIA 收起 <<	Phase 2 Phase 3	Unknown	July 2016	China, Shaanxi ... 展开 >> Xijing Hospital Not yet recruiting Xi'an, Shaanxi, China, 710032 Contact: Fang Yang, M.D. Ph.D. +86 029 84773214 fyangx@fmmu.edu.cn Principal Investigator: Gang Zhao, M.D. 收起 <<
NCT03045406	Venous Thromboembolism	Phase 3	Recruiting	June 2019	-
NCT03441633	-		Completed	-	Spain ... 展开 >> IDIAP Jordi Gol Barcelona, Cataluña, Spain, 8007 收起 <<
NCT02179177	Vaso-occlusive Crisis ... 展开 >> Reduction in Hospitalizations Sickle Cell Disease 收起 <<	Phase 3	Recruiting	September 30, 2019	United States, North Carolina ... 展开 >> Duke University Medical Center Recruiting Durham, North Carolina, United States, 27710 Contact: Betty Thames, BSN 919-681-9564 elizabeth.thames@dm.duke.edu Contact: Sheila Adams 919-684-2406 sheila.lambertadams@dm.duke.edu 收起 <<
NCT00496769	Atrial Fibrillation	Phase 3	Completed	-	-
NCT02836457	-		Recruiting	June 2019	Japan ... 展开 >> Local Institution Recruiting Shinjuku-ku, Tokyo, Japan, 162-0822 Contact: Site 0001 收起 <<
NCT02687854	-		Completed	-	United States, New York ... 展开 >> New York, New York, United States 收起 <<
NCT00496769	-		Completed	-	-
NCT00457002	Venous Thrombosis ... 展开 >> Pulmonary Embolism 收起 <<	Phase 3	Completed	-	-
NCT01885598	-		Completed	-	Korea, Republic of ... 展开 >> Local Institution Seoul, Korea, Republic of, 110-756 收起 <<
NCT02981472	Thrombosis	Phase 2	Recruiting	October 1, 2021	-
NCT02415400	Acute Coronary Syndromes	Phase 4	Completed	-	-
NCT02283294	Transient Ischemic Attack ... 展开 >> Stroke Atrial Fibrillation 收起 <<	Phase 3	Recruiting	December 2018	United States, California ... 展开 >> Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Recruiting Torrance, California, United States, 90502 Contact: Jason Ledesma jason.ledesma@labiomed.org Principal Investigator: Bijal Mehta, MD United States, Florida Bayfront Health St Petersburg Recruiting Saint Petersburg, Florida, United States, 33701 Contact: Kimberly Delmontagne, RN kimberly.delmontagne@bayfronthealth.com Contact: Tina Henderson tina.henderson@bayfronthealth.com Principal Investigator: Ravikiran Korabathina, MD Tampa General Hospital Recruiting Tampa, Florida, United States, 33602 Contact: Anderson Brabson, MS, MHSA c-rbrabson@tgh.org Principal Investigator: Arthur Labovitz, MD Sub-Investigator: W. Scott Burgin, MD Sub-Investigator: David Rose, MD Sub-Investigator: Swetha Renati, MD University of South Florida Recruiting Tampa, Florida, United States, 33602 Contact: Nhi Tran, MS 813-259-0628 nntran@health.usf.edu Principal Investigator: Arthur Labovitz, MD Sub-Investigator: W. Scott Burgin, MD Sub-Investigator: David Rose, MD Sub-Investigator: Swetha Renati, MD Sub-Investigator: Michael Fradley, MD United States, Kentucky University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Rita Longaker, RN 502-386-4134 rita.longaker@louisville.due Principal Investigator: Marcus Stoddard, MD 收起 <<
NCT01340586	End Stage Renal Disease	Phase 1	Completed	-	United States, Florida ... 展开 >> Orlando, Florida, United States 收起 <<
NCT01340586	-		Completed	-	-
NCT02559856	Venous Thromboembolism	Phase 4	Completed	-	Canada, Ontario ... 展开 >> The Ottawa Hospital - General Campus Ottawa, Ontario, Canada, K1H 8L6 收起 <<
NCT02585713	Cerebral Vein Thrombosis ... 展开 >> Deep Vein Thrombosis Gonadal Thrombosis Hepatic Thrombosis Malignant Neoplasm Mesenteric Thrombosis Metastatic Malignant Neoplasm Portal Vein Thrombosis Pulmonary Embolism Renal Vein Thrombosis Splenic Thrombosis Venous Thromboembolism 收起 <<	Phase 3	Active, not recruiting	November 20, 2018	United States, Arizona ... 展开 >> Mayo Clinic in Arizona Scottsdale, Arizona, United States, 85259 United States, Florida Mayo Clinic in Florida Jacksonville, Florida, United States, 32224-9980 United States, Illinois NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois, United States, 60201 Illinois CancerCare-Peoria Peoria, Illinois, United States, 61615 United States, Iowa University of Iowa/Holden Comprehensive Cancer Center Iowa City, Iowa, United States, 52242 Siouxland Regional Cancer Center Sioux City, Iowa, United States, 51101 United States, Kansas Cancer Center of Kansas - Wichita Wichita, Kansas, United States, 67214 United States, Michigan Cancer Research Consortium of West Michigan NCORP Grand Rapids, Michigan, United States, 49503 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 Coborn Cancer Center at Saint Cloud Hospital Saint Cloud, Minnesota, United States, 56303 Metro Minnesota Community Oncology Research Consortium Saint Louis Park, Minnesota, United States, 55416 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 United States, New Hampshire New Hampshire Oncology Hematology PA-Hooksett Hooksett, New Hampshire, United States, 03106 United States, North Carolina FirstHealth of the Carolinas-Moore Regional Hosiptal Pinehurst, North Carolina, United States, 28374 United States, Ohio Columbus NCI Community Oncology Research Program Columbus, Ohio, United States, 43215 Toledo Clinic Cancer Centers-Toledo Toledo, Ohio, United States, 43623 United States, Pennsylvania Guthrie Medical Group PC-Robert Packer Hospital Sayre, Pennsylvania, United States, 18840 United States, South Dakota Rapid City Regional Hospital Rapid City, South Dakota, United States, 57701 收起 <<
NCT02912234	Venous Thromboembolism	Phase 1	Completed	-	United States, Texas ... 展开 >> Ppd Development, Llc Austin, Texas, United States, 78744 收起 <<
NCT02464969	Venous Thromboembolism	Phase 4	Recruiting	April 29, 2021	-
NCT00457002	-		Completed	-	-
NCT03288454	Healthy	Phase 2	Recruiting	January 2019	United States, New Jersey ... 展开 >> Frontage Clinical Services Inc. Recruiting Secaucus, New Jersey, United States, 07094 Contact: Alexander N. Prezioso, MD 201-416-7747 aprezioso@frontaglab.com Principal Investigator: Alexander N Prezioso, MD 收起 <<
NCT02829957	Venous Thromboembolism ... 展开 >> Menstruation 收起 <<	Phase 2 Phase 3	Recruiting	December 2020	United States, Indiana ... 展开 >> Eskenazi Health System Recruiting Indianapolis, Indiana, United States, 46202 Indiana University Health Methodist Hospital Recruiting Indianapolis, Indiana, United States, 46202 收起 <<
NCT02295475	Antiphospholipid Syndrome ... 展开 >> Thrombosis 收起 <<	Phase 4	Recruiting	December 2019	United States, Utah ... 展开 >> Intermountain Medical Center Recruiting Murray, Utah, United States, 84157 Contact: Shauna Bruun 801-408-2137 Shauna.Bruun@imail.org 收起 <<
NCT01195727	Venous Thromboembolism	Phase 1	Terminated	-	United States, California ... 展开 >> Children'S Hospital Of Orange County Orange, California, United States, 92868 United States, New Jersey Saint Peter'S University Hospital New Brunswick, New Jersey, United States, 08901 United States, Ohio The Toledo Children'S Hospital Toledo, Ohio, United States, 43606 United States, Pennsylvania Penn State Hershey Children'S Hospital Hershey, Pennsylvania, United States, 17033 Belgium Local Institution Bruxelles, Belgium, 1020 Local Institution Leuven, Belgium, 3000 Canada, Alberta Local Institution Edmonton, Alberta, Canada, T6G 2B7 Canada, Ontario Local Institution Ottawa, Ontario, Canada, K1H 8L1 Mexico Local Institution Mexico City, Distrito Federal, Mexico, 14080 Local Institution Mexico, D. F., Distrito Federal, Mexico, 11000 Local Institution Mexico, Distrito Federal, Mexico, 04530 Local Institution Guadalajara, Jalisco, Mexico, 44340 Local Institution Puebla, Mexico, 72190 Netherlands Local Institution Amsterdam, Netherlands, 1105 AZ 收起 <<
NCT02048865	Venous Thromboembolism ... 展开 >> Cancer 收起 <<	Phase 2	Completed	-	Canada, British Columbia ... 展开 >> Vancouver General Hospital Vancouver, British Columbia, Canada, V5Z 1M9 Canada, Nova Scotia Capital District Health Authority Halifax, Nova Scotia, Canada, B3H 1V7 Canada, Ontario Royal Victoria Regional Health Centre (RVH) Barrie, Ontario, Canada, L4M 6M2 William Osler Health System -Brampton Brampton, Ontario, Canada, L6R 3J7 Juravinski Hospital & Cancer Centre Hamilton, Ontario, Canada, L8V 1C3 Kingston General Hospital Kingston, Ontario, Canada, K7L 2V7 London Health Sciences Center London, Ontario, Canada, N6A 5W9 Lakeridge Health -Oshawa Oshawa, Ontario, Canada Ottawa Hospital-General Campus Ottawa, Ontario, Canada, K1H 8L6 Sault Area Hospital Sault Ste. Marie, Ontario, Canada, P6B 0A8 Markham Stouffville Hospital Toronto, Ontario, Canada, L3P 7P3 Canada, Quebec Centre intégré de santé et de services sociaux de l'Outaouais - Gatineau Gatineau, Quebec, Canada, J8P 7H2 Jewish General Hospital Montreal, Quebec, Canada, H3T 1E2 Centre intégré de santé et de services sociaux du Bas St Laurent -Rimouski Rimouski, Quebec, Canada 收起 <<
NCT02714855	-		Completed	-	France ... 展开 >> Local Institution Fontaine Les Dijon, France, 21121 收起 <<
NCT03590743	Deep Vein Thrombosis	Phase 4	Recruiting	December 31, 2021	United States, Minnesota ... 展开 >> Mayo Clinic in Rochester Recruiting Rochester, Minnesota, United States, 55905 United States, Wisconsin Mayo Clinic Recruiting Eau Claire, Wisconsin, United States, 54701 Contact: Andrew Calvin, MD 715-838-6836 calvin.andrew@mayo.edu Contact: Holly Hennlich 715-464-8172 hennlich.holly@mayo.edu Mayo Clinic Recruiting La Crosse, Wisconsin, United States, 54601 Contact: Carolyn R Flock 608-392-9462 Flock.Carolyn@mayo.edu Contact: Patsy Cacerers Figueroa 608-392-9280 caceresfigueroa.patsy@mayo.edu 收起 <<
NCT03746782	-		Recruiting	July 2019	United States, Tennessee ... 展开 >> CirQuest Labs, LLC Recruiting Memphis, Tennessee, United States, 38112 Contact: Carol Hendrix, MSN, RN 901-866-1700 chendrix@cirquestlabs.com Contact: Edward Hord, BSN, RN 901-866-1700 ehord@cirquestlabs.com Principal Investigator: Jayaprakash Kotha, PhD Sub-Investigator: Frank McGrew, MD Sub-Investigator: Lisa Jennings, PhD 收起 <<
NCT02427126	Embolic Stroke	Phase 3	Recruiting	December 2019	Germany ... 展开 >> Klinik für NeurologieKnappschaftskrankenhaus Bochum-Langendreer Recruiting Bochum, Germany Contact: Uwe Schlegel, MD Neurologische Klinik, Universität Bonn Recruiting Bonn, Germany Contact: Gabor Petzold, Dr. med. Klinikum Coburg GmbH II Recruiting Coburg, Germany Contact: Johannes Brachmann, Prof Neurologie, Klinikum Friedrichshafen GmbH Recruiting Friedrichshafen, Germany Contact: R Huber, Prof Universitätsmedizin GöttingenAbt. Innere Medizin, Klinik für Kardiologie und Pneumologie, Recruiting Göttingen, Germany Contact: Rolf Wachter, MD Neurologische Klinik Städtische Kliniken Karlsruhe,Städtisches Klinikum Karlsruhe gGmbH Not yet recruiting Karlsruhe, Germany Contact: Gahn, Prof Klinik für Neurolgie,UKSH Campus Kiel Not yet recruiting Kiel, Germany Contact: Andreas Binder, MD Klinik für Neurologie, Klinikum Ludwigsburg Recruiting Ludwigsburg, Germany Contact: Martin Schabet, Prof Carl von Basedow KlinikumSaalekreis gGmbH Not yet recruiting Merseburg, Germany Contact: Carsten Hobohm, MD Marienhospital Stuttgart, Klinik für Neurologie Recruiting Stuttgart, Germany Contact: Alfred Lindner, Prof Neurologische Klinik des Bürgerhospitals Recruiting Stuttgart, Germany Contact: Elisabeth Schmid, Dr. med. University Hospital Recruiting Tubingen, Germany, D72076 Contact: Tobias Geisler, Prof Contact: Timea Keller, Mrs Principal Investigator: Tobias Geisler, Prof Sub-Investigator: Sven Poli, MD Sub-Investigator: Jürgen Schreieck, MD Universitäts- und Rehabilitationskliniken Ulm,Klinik für Neurologie Recruiting Ulm, Germany Contact: Katharina Althaus, Dr Schwarzwald Baar Klinikum GmbH Recruiting Villingen-Schwenningen, Germany Contact: Werner Jung, Prof Rems-Murr-Klinikum WinnendenNeurologie Recruiting Winnenden, Germany Contact: Fabian Hillenbrand, MD 收起 <<
NCT03200613	Spinal Cord Injuries ... 展开 >> Venous Thromboembolism 收起 <<	Phase 2	Recruiting	November 1, 2019	Canada, Ontario ... 展开 >> Hamilton General Hospital Recruiting Hamilton, Ontario, Canada, L8L 2X2 Principal Investigator: Sam Schulman, MD, PhD Principal Investigator: Siavash Piran, MD, MSc 收起 <<
NCT02958969	Venous Thromboembolism ... 展开 >> Multiple Myeloma 收起 <<	Phase 4	Active, not recruiting	June 2019	United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 收起 <<
NCT01707394	Thromboembolism	Phase 1	Recruiting	December 31, 2019	-
NCT02666742	Ventricular Tachycardia	Phase 4	Terminated(Investigator left I... 展开 >>nstitution.) 收起 <<	-	United States, Kansas ... 展开 >> University of Kansas Medical Center Kansas City, Kansas, United States, 66160 收起 <<
NCT02345343	-		Completed	-	Mexico ... 展开 >> Local Institution Queretaro, Mexico, 76000 收起 <<
NCT02366871	Gynecologic Cancer ... 展开 >> Venous Thromboembolism 收起 <<	Phase 2	Recruiting	March 2019	United States, Colorado ... 展开 >> University of Colorado Denver Recruiting Aurora, Colorado, United States, 80045 收起 <<
NCT02034565	-		Completed	-	-
NCT02262533	N/A - Healthy Subjects	Phase 1	Completed	-	United States, New Jersey ... 展开 >> Bms Clinical Research Center Hamilton, New Jersey, United States, 08690 收起 <<
NCT02262520	N/A - Healthy Subjects	Phase 1	Completed	-	-
NCT02034565	Healthy Volunteers	Phase 1	Completed	-	United States, New Jersey ... 展开 >> Mds Pharma Services Neptune, New Jersey, United States, 07753 收起 <<
NCT02090075	Atrial Fibrillation	Phase 4	Completed	-	United States, California ... 展开 >> Los Angeles Biomedical Research Institute Torrance, California, United States, 90502 收起 <<
NCT01938248	Atrial Fibrillation ... 展开 >> Stroke 收起 <<	Phase 4	Recruiting	April 2021	-
NCT01884337	Anticoagulation	Phase 4	Recruiting	December 31, 2018	India ... 展开 >> Local Institution Withdrawn Pune, Maharashtra, India, 422001 Local Institution Active, not recruiting Ahmedabad, India, 380015 Local Institution Active, not recruiting Ahmedabad, India, 380016 Local Institution Active, not recruiting Ahmedabad, India, 380060 Local Institution Not yet recruiting Alappuzha, India, 688005 Contact: Site 0072 Local Institution Active, not recruiting Aurangabad, India, 431003 Local Institution Active, not recruiting Bangalore, India, 560054 Local Institution Not yet recruiting Chandigarh, India, 160012 Contact: Site 0040 Local Institution Withdrawn Chennai, India, 600001 Local Institution Recruiting Chennai, India, 600010 Contact: Site 0053 Local Institution Active, not recruiting Delhi, India, 110029 Local Institution Active, not recruiting Hyderabad, India, 500001 Local Institution Active, not recruiting Kerala, India, 695011 Local Institution Active, not recruiting Lucknow, India, 226003 Local Institution Active, not recruiting Mohali, India, 160062 Local Institution Active, not recruiting Mumbai, India, 400022 Local Institution Active, not recruiting Nagpur, India, 440009 Local Institution Not yet recruiting Pune, India, 411001 Contact: Site 0070 Local Institution Active, not recruiting Pune, India, 411004 Local Institution Recruiting Pune, India, 411005 Contact: Site 0062 Local Institution Active, not recruiting Pune, India, 411013 收起 <<
NCT02982590	Left Ventricular Thrombosis	Phase 3	Recruiting	December 2018	Malaysia ... 展开 >> Hospital Universiti Sains Malaysia Recruiting Kota Bharu, Kelanatan, Malaysia, 16150 Contact: Dr W. Yus Haniff W. Isa 60199228373 收起 <<
NCT02074358	-		Completed	-	-
NCT02034591	Healthy Subjects	Phase 1	Completed	-	United States, Texas ... 展开 >> Healthcare Discoveries, LLC D/B/A Icon Development Solutions San Antonio, Texas, United States, 78209 收起 <<
NCT02034591	-		Completed	-	-
NCT03199521	-		Recruiting	March 2019	United Kingdom ... 展开 >> Hertfordshire Cardiology Centre, East and North Hertfordshire NHS Trust Recruiting Stevenage, United Kingdom, SG14AB Contact: Dr Phillip Smith 02038262162 phillip.smith5@nhs.net 收起 <<
NCT02074358	Anticoagulation	Phase 1	Completed	-	-
NCT03448783	-		Recruiting	December 2026	Norway ... 展开 >> St. Olavs University Hospital Recruiting Trondheim, Norway Contact: Magnus Strømmen, MSc 收起 <<
NCT03232398	Acute Myocardial Infarction ... 展开 >> Left Ventricular Thrombosis Anticoagulants and Bleeding Disorders 收起 <<	Phase 3	Not yet recruiting	October 31, 2019	Israel ... 展开 >> Hadassah Medical Organization Jerusalem, Israel 收起 <<
NCT03266783	Venous Thromboembolism	Phase 4	Recruiting	May 2022	Canada, Alberta ... 展开 >> University of Calgary Not yet recruiting Calgary, Alberta, Canada Contact: Deepa Suryanarayan, MD Alberta Health Sciences Recruiting Edmonton, Alberta, Canada Contact: Cynthia Wu, MD Canada, British Columbia St. Paul's Hospital Not yet recruiting Vancouver, British Columbia, Canada Contact: Tony Wan, MD Canada, Nova Scotia QEII Health Science Centre Recruiting Halifax, Nova Scotia, Canada, B3H 2Y9 Contact: Sudeep Shivakumar, MD Canada, Ontario Cornwall Hospital Not yet recruiting Cornwall, Ontario, Canada Contact: Nancy McDonald, RN Hamilton General Hospital Recruiting Hamilton, Ontario, Canada Contact: Kerstin de Wit, MD Juravinski Hospital Recruiting Hamilton, Ontario, Canada Contact: Kerstin de Wit, MD St. Joseph's Healthcare Hamilton Recruiting Hamilton, Ontario, Canada Contact: James Douketis, MD London Health Sciences Center Not yet recruiting London, Ontario, Canada, N6A 5W9 Contact: Michael Kovacs, MD The Ottawa Hospital - General Campus Recruiting Ottawa, Ontario, Canada, K1H 8L6 Contact: Lana Castellucci, MD, FRCPC 613-737-8899 ext 73682 lcastellucci@toh.on.ca Contact: Yan Yu He, MSc 613-737-8899 ext 72103 yahe@ohri.ca Principal Investigator: Lana Castellucci, MD, FRCPC Sub-Investigator: Marc Carrier, MD, FRCPC Canada, Quebec St. Mary's Hospital Not yet recruiting Montreal, Quebec, Canada Contact: Susan Solymoss, MD Jewish General Hospital Not yet recruiting Montréal, Quebec, Canada, H3T 1E2 Contact: Susan Kahn, MD, FRCPC McGill University Health Center Not yet recruiting Montréal, Quebec, Canada, H4A 3J1 Contact: Susan Solymoss, MD , CHU de Québec- Enfant-Jésus Not yet recruiting Quebec city, Quebec, Canada Contact: Benoit Cote, MD 收起 <<
NCT02378623	Patent Foramen Ovale ... 展开 >> Cardiac Implantable Electronic Device 收起 <<	Phase 2	Withdrawn(Sponsor withdrew fun... 展开 >>ding - May 2016) 收起 <<	January 2020	United States, Minnesota ... 展开 >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 收起 <<
NCT02153424	-		Withdrawn(Business objectives ... 展开 >>have changed.) 收起 <<	-	Mexico ... 展开 >> Local Institution Guadalajara, Jalisco, Mexico, 442003 Local Institution Puebla, Mexico, 72040 收起 <<
NCT02933697	Atrial Fibrillation ... 展开 >> End-stage Kidney Disease 收起 <<	Phase 3	Recruiting	April 2019	Germany ... 展开 >> Universitätsklinikum Münster Recruiting Münster, Germany, 48149 收起 <<
NCT03080883	Cerebral Vein Thrombosis ... 展开 >> Deep Vein Thrombosis Malignant Neoplasm Metastatic Malignant Neoplasm Pulmonary Embolism Splanchnic Vein Thrombosis 收起 <<	Phase 3	Recruiting	May 1, 2023	United States, Arizona ... 展开 >> Mayo Clinic in Arizona Not yet recruiting Scottsdale, Arizona, United States, 85259 Contact: Leslie J. Padrnos Padrnos.Leslie@mayo.edu Principal Investigator: Leslie J. Padrnos United States, Florida Mayo Clinic in Florida Not yet recruiting Jacksonville, Florida, United States, 32224-9980 Contact: Prakash Vishnu Vishnu.Prakash@mayo.edu Principal Investigator: Prakash Vishnu United States, Illinois Illinois Cancer Center Recruiting Chicago, Illinois, United States, 60603 Contact: Nadia Q. Rehman nrehman@illinoiscancercare.com Principal Investigator: Nadia Q. Rehman NorthShore University HealthSystem-Evanston Hospital Recruiting Evanston, Illinois, United States, 60201 Contact: Michele Britto 224-251-4705 mbritto@northshore.org Principal Investigator: Alfonso J. Tafur Carle Cancer Center Not yet recruiting Urbana, Illinois, United States, 61801 Contact: Elizabeth Barnick 217-383-3010 betsy.barnick@carle.com Principal Investigator: Vamsi K. Vasireddy United States, Iowa University of Iowa/Holden Comprehensive Cancer Center Recruiting Iowa City, Iowa, United States, 52242 Contact: Karen Parrott 319-353-6347 karen-parrott@uiowa.edu Principal Investigator: Usha S. Perepu United States, Kansas Cancer Center of Kansas - Wichita Recruiting Wichita, Kansas, United States, 67214 Contact: Pat Stone 316-262-4467 pat.stone@cancercenterofkansas.com Principal Investigator: Shaker R. Dakhil United States, Kentucky Saint Elizabeth Medical Center South Recruiting Edgewood, Kentucky, United States, 41017 Contact: Sara Browne 859-301-4046 sara.browne@stelizabeth.com Principal Investigator: Colleen M. Darnell United States, Michigan University of Michigan Comprehensive Cancer Center Recruiting Ann Arbor, Michigan, United States, 48109 Contact: Patricia Bebee 734-763-4457 pbe@med.umich.edu Principal Investigator: John C. Krauss United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Kim Hitchcock 507-266-3964 hitchcock.kimberly@mayo.edu Principal Investigator: Robert D. McBane Metro Minnesota Community Oncology Research Consortium Recruiting Saint Louis Park, Minnesota, United States, 55416 Contact: Elizabeth J. Wagner 952-993-1555 elizabethwagner@gmail.com Principal Investigator: Daniel M. Anderson United States, Missouri Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Caroline M. Bumb 314-362-7249 cbumb@dom.wustl.edu Principal Investigator: Tanya M. Wildes United States, Nebraska University of Nebraska Medical Center Not yet recruiting Omaha, Nebraska, United States, 68198 Contact: Krishna Gundabolu krishna.gundabolu@unmc.edu Principal Investigator: Krishna Gundabolu United States, New Hampshire New Hampshire Oncology Hematology PA-Hooksett Recruiting Hooksett, New Hampshire, United States, 03106 Contact: Douglas J. Weckstein 603-622-6484 d.weckstein@nhoh.com Principal Investigator: Douglas J. Weckstein Dartmouth Hitchcock Medical Center Recruiting Lebanon, New Hampshire, United States, 03756 Contact: Julie D. Schettino 603-650-2967 Julie.D.Schettino@hitchcock.org Principal Investigator: Monic R. Drescher United States, North Carolina UNC Lineberger Comprehensive Cancer Center Recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Marcus A. Layer 919-966-4432 marcus_layer@med.unc.edu Principal Investigator: Micah J. Mooberry Duke University Medical Center Recruiting Durham, North Carolina, United States, 27710 Contact: Wendy A. Bloomer 919-668-6716 wendy.bloomer@duke.edu Principal Investigator: Ewa M. Wysokinska Cone Health Cancer Center Withdrawn Greensboro, North Carolina, United States, 27403 FirstHealth of the Carolinas-Moore Regional Hospital Recruiting Pinehurst, North Carolina, United States, 28374 Contact: Lori DeSpain 910-715-3500 ldespain@firsthealth.org Principal Investigator: Charles S. Kuzma United States, North Dakota Altru Cancer Center Not yet recruiting Grand Forks, North Dakota, United States, 58201 Contact: Robert D. McBane 507-284-4565 Principal Investigator: Robert D. McBane United States, Wisconsin Marshfield Clinic Not yet recruiting Marshfield, Wisconsin, United States, 54449 Contact: Debra D. Schillinger 715-387-5416 Schillinger.Debra@mcrf.mfldclin.edu Principal Investigator: Chady A. Leon 收起 <<
NCT02101112	Thrombosis	Phase 1	Completed	-	-
NCT01884350	Non-valvular Atrial Fibrillati... 展开 >>on 收起 <<	Phase 4	Completed	-	-
NCT02581176	Neoplasms Ven... 展开 >>ous Thrombosis 收起 <<	Phase 4	Completed	-	Norway ... 展开 >> Haukeland University Hospital Bergen, Norway Vestre Viken- Drammen Hospital Drammen, Norway Vestre Viken - Bærum sykehus Gjettum, Norway, 1346 Department of Hematology, Akershus University Hospital Lørenskog, Norway, 1478 Oslo University Hospital Oslo, Norway Østfold Hospital Kalnes Sarpsborg, Norway Stavanger University Hospital Stavanger, Norway St. Olavs Hospital Trondheim, Norway Volda Hospital Volda, Norway 收起 <<
NCT03136510	Coagulation Disorder ... 展开 >> Non Valvular Atrial Fibrillation 收起 <<	Not Applicable	Recruiting	June 2018	France ... 展开 >> Department of Cardiology Lariboisiere Hospital Recruiting Paris, France, 75010 Contact: Claire Bal dit Sollier (33) 1 49 95 85 78 claire.bal@aphp.fr 收起 <<
NCT02034578	Healthy Volunteers	Phase 1	Completed	-	United States, Maryland ... 展开 >> Parexel Baltimore Early Phase Clinical Unit Baltimore, Maryland, United States, 21225 收起 <<
NCT02101112	-		Completed	-	-
NCT02809469	Atrial Fibrillation	Phase 2	Unknown	August 2018	Canada, Ontario ... 展开 >> Hamilton General Hospital Hamilton, Ontario, Canada, L8L 2X2 收起 <<
NCT02889562	Coronary Artery Bypass Graftin... 展开 >>g Postoperative Atrial Fibrilation Stroke Systemic Embolism Deep Venous Thrombosis 收起 <<	Phase 2 Phase 3	Recruiting	December 2018	United States, North Dakota ... 展开 >> Sanford Health Recruiting Fargo, North Dakota, United States, 58122 Contact: Elizabeth Eidenschink 701-234-6298 elizabeth.eidenschink@sanfordhealth.org Principal Investigator: Cornelius Dyke, MD Sub-Investigator: Todd Chapin, PharmD 收起 <<
NCT03456648	ESRD Anticoag... 展开 >>ulant Toxicity 收起 <<	Phase 2	Completed	-	Belgium ... 展开 >> University Hospitals Leuven Leuven, Vlaams-brabant, Belgium, 3000 收起 <<
NCT02406885	Bariatric Surgery ... 展开 >> Obesity 收起 <<	Phase 4	Recruiting	December 2020	United States, Maryland ... 展开 >> The Johns Hopkins Center for Bariatric Surgery Recruiting Baltimore, Maryland, United States, 21224 Contact: Kimberely E Steele, MD, PhD 410-550-0409 Contact: Dene Palazzi-Kahn 410-443-287-8610 Principal Investigator: Kimberley E Steele, MD, PhD Principal Investigator: Grant G Petty, MD Sub-Investigator: Michael A Schweitzer, MD Sub-Investigator: Thomas H Magnuson, MD 收起 <<
NCT02034578	-		Completed	-	-
NCT03594045	Heparin-induced Thrombocytopen... 展开 >>ia Heparin-induced Thrombocytopenia and Thrombosis 收起 <<	Phase 2	Recruiting	December 31, 2025	United States, Massachusetts ... 展开 >> Massachusetts General Hospital Recruiting Boston, Massachusetts, United States, 02214 Contact: Rachel P. Rosovsky, MD 617-724-4000 rprosovsky@partners.org Principal Investigator: Rachel P. Rosovsky, M Beth Israel Deaconess Medical Center Recruiting Boston, Massachusetts, United States, 02215 Contact: Jefftrey Zwicker, MD jzwicker@bidmc.harvard.edu Principal Investigator: Jeffrey Zwicker, MD Brigham and Women Hospital Not yet recruiting Boston, Massachusetts, United States, 02215 Contact: Jean Marie Connors, MD JCONNORS@PARTNERS.ORG Principal Investigator: Jean Marie Connors, MD 收起 <<
NCT02935751	-		Completed	-	United States, Pennsylvania ... 展开 >> Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 收起 <<
NCT03678506	Venous Thromboembolism ... 展开 >> Anticoagulants 收起 <<	Phase 4	Recruiting	January 2022	Italy ... 展开 >> Daniela Poli Recruiting Firenze, Italy, 50134 收起 <<
NCT03083782	Venous Thromboembolism ... 展开 >> Pharmacokinetics Healthy 收起 <<	Phase 1	Completed	-	United States, Pennsylvania ... 展开 >> Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 收起 <<
NCT02672709	End-stage Renal Disease	Phase 4	Completed	-	Canada ... 展开 >> Jewish General Hospital Montreal, Canada 收起 <<
NCT02599532	Nephrotic Syndrome ... 展开 >> Proteinuria 收起 <<	Phase 1	Recruiting	April 2019	United States, North Carolina ... 展开 >> University of North Carolina at Chapel Hill Recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Daniel Crona, PharmD, PhD 919-966-4343 crona@email.unc.edu Contact: Andy Szeto, PharmD 919-445-2760 ahszeto@email.unc.edu Sub-Investigator: Vimal Derebail, MD Sub-Investigator: Nigel Key, MD 收起 <<
NCT02450682	Atrial Fibrillation	Phase 2	Withdrawn	March 2017	United States, Minnesota ... 展开 >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 收起 <<
NCT02945280	Deep Venous Thrombosis ... 展开 >> Upper Extremity Deep Venous Thrombosis Thrombus Venous Thromboembolism Deep Vein Thrombosis 收起 <<	Phase 4	Recruiting	October 2019	United States, Utah ... 展开 >> Intermountain Medical Center Recruiting Murray, Utah, United States, 84107 Contact: Scott Woller, MD 801-507-7000 Scott.Woller@imail.org Principal Investigator: Stacey Johnson, MD Sub-Investigator: Scott Stevens, MD University of Utah Not yet recruiting Salt Lake City, Utah, United States, 84132 Contact: Mary J Tinnes 801-585-2254 maryjane.tinnes@hsc.utah.edu Contact: Stacy Johnson, MD 801-581-7822 stacy.johnson@hsc.utah.edu 收起 <<
NCT03509883	Healthy Volunteers	Phase 1	Completed	-	United States, Texas ... 展开 >> PPD Austin Clinic Austin, Texas, United States, 78744 收起 <<
NCT03073265	-		Completed	-	United States, North Carolina ... 展开 >> Moses Cone Memorial Hospital Greensboro, North Carolina, United States, 27401 United States, Pennsylvania Lehigh Valley Health Nrwork Allentown, Pennsylvania, United States, 18101 收起 <<
NCT02608099	Atrial Fibrillation	Phase 4	Completed	-	-
NCT03692065	Cancer-associated Thrombosis	Phase 3	Not yet recruiting	April 30, 2023	-
NCT02749617	Anti-Xa Activity	Phase 2	Recruiting	May 2018	Canada, British Columbia ... 展开 >> Vancouver General Hospital Recruiting Vancouver, British Columbia, Canada, V5Z 1M9 Contact: Agnes Lee, MD MSc FRCPC 收起 <<
NCT03610217	Scleroderma, Systemic ... 展开 >> Sclerosis, Systemic 收起 <<	Not Applicable	Not yet recruiting	October 2021	Canada, Ontario ... 展开 >> Saint Joseph's Health Care London Not yet recruiting London, Ontario, Canada, n6a 4v2 Contact: Janet E Pope, MD, MPH, FRCPSC 15196466332 Janet.Pope@sjhc.london.on.ca Contact: Andreu Fernandez-Codina 151964661023 doccodina@gmail.com 收起 <<
NCT03367325	Atrial Fibrillation ... 展开 >> Anticoagulants Clinical Decision Support Systems 收起 <<	Not Applicable	Not yet recruiting	December 15, 2019	-
NCT03182218	-		Completed	-	Spain ... 展开 >> Hospital de Mataró Mataró, Barcelona, Spain, 08304 Hospital de Sabadell-Parc Taulí Sabadell, Barcelona, Spain, 08208 Hospital Universitario Marques de Valdecilla Santander, Cantabria, Spain, 39008 Hospital Universitario Severo Ochoa Leganés, Madrid, Spain, 28911 Hospital Universitario de Canarias La Laguna, Tenerife, Spain, 38320 Hospital de Manises Manises, Valencia, Spain, 46940 Hospital Universitario La Ribera Alzira, Spain, 46600 Parc Salut Mar Barcelona, Spain, 08003 Fundació Puigvert Barcelona, Spain, 08025 Hospital Universitario Vall d'Hebron Barcelona, Spain, 08035 Hospital Puerta del Mar Cadiz, Spain, 11009 Hospital de Galdakao-Usánsolo Galdakao, Spain, 48960 Hospital Universitario de Getafe Getafe, Spain, 28905 Hospital Universitario de Gran Canaria Doctor Negrín Las Palmas de Gran Canaria, Spain, 35012 Hospital General Universitario Gregorio Marañón Madrid, Spain, 28009 Hospital Universitario Infanta Leonor Madrid, Spain, 28031 Hospital Universitario La Paz Madrid, Spain, 28046 Hospital Virgen de la Victoria Malaga, Spain, 29010 Hospital Costa del Sol Marbella, Spain, 29600 Hospital Universitario de Móstoles Móstoles, Spain, 28935 Clínica Universidad de Navarra Pamplona, Spain, 31008 Hospital General de Segovia Segovia, Spain, 40006 Hospital Universitario Virgen del Rocío Sevilla, Spain, 41013 Hospital Virgen de la Salud Toledo, Spain, 45004 Hospital Clínico Universitario Valencia, Spain, 46010 Consorcio H. General Universitario de Valencia Valencia, Spain, 46014 Hospital Universitari i Politècnic La Fe Valencia, Spain, 46016 Hospital Dr Peset Valencia, Spain, 46017 Hospital Lluís Alcanyís Xàtiva, Spain, 46800 Hospital Miguel Servet Zaragoza, Spain, 50009 收起 <<
NCT02635230	-		Active, not recruiting	December 2019	Netherlands ... 展开 >> Amphia Hospital Breda, Noord-Brabant, Netherlands, 4818 CK 收起 <<
NCT01727427	-		Completed	-	-
NCT02353585	-		Recruiting	December 2018	Switzerland ... 展开 >> Stroke Center Recruiting Basel, Switzerland, 4031 Contact: David Seiffge, MD 0041-61-3287278 david.seiffge@usb.ch Principal Investigator: David Seiffge, MD 收起 <<
NCT02238470	-		Completed	-	Italy ... 展开 >> Arcispedale Santa Maria Nuova IRCCS Reggio Emilia, Italy Spain Hospital Germans Trias i Pujol Badalona, Barcelona, Spain Fundació Hospital Asil Granollers Granollers, Barcelona, Spain Hospital de Mataró Mataró, Barcelona, Spain Hospital Parc Taulí Sabadell, Barcelona, Spain Hospital Moisés Broggi Sant Joan Despí, Barcelona, Spain Mutua de Terrassa Terrassa, Barcelona, Spain Hospital de la Cinta Tortosa, Tarragona, Spain Hospital de Albacete Albacete, Spain Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Hospital Clínic Barcelona, Spain Hospital del Mar Barcelona, Spain Hospital de Basurto Bilbao, Spain Hospital CA de Burgos Burgos, Spain Hospital San Pedro de Alcántara Cáceres, Spain Hospital de Donostia Donostia, Spain Hospital Virgen de las Nieves Granada, Spain Hospital de León León, Spain Hospital Arnau de Vilanova Lleida, Spain Hospital La Rioja Logroño, Spain Hospital Gregorio Marañón Madrid, Spain Hospital Ramón y Cajal Madrid, Spain Hospital Universitario La Paz Madrid, Spain Centro Médico Asturias Oviedo, Spain Hospital Son Espases Palma de Mallorca, Spain Hospital de Navarra Pamplona, Spain CHU Santiago de Compostela Santiago de Compostela, Spain Hospital Virgen del Rocío Sevilla, Spain Hospital La Fe Valencia, Spain Hospital CU de Valladolid Valladolid, Spain 收起 <<
NCT02219984	-		Active, not recruiting	July 2019	Italy ... 展开 >> S. Orsola-Malpighi University hospital Bologna, BO, Italy, 40138 收起 <<
NCT03002740	-		Withdrawn	August 31, 2018	-
NCT03465735	Acute DVT of Lower Extremity	Not Applicable	Enrolling by invitation	December 2018	United States, Minnesota ... 展开 >> Mayo Clinic Rochester, Minnesota, United States, 55905 收起 <<
NCT02982863	-		Completed	-	Japan ... 展开 >> NISED Center Tokyo, Shinagawa, Japan, 1416017 收起 <<
NCT02982863	-		Completed	-	-
NCT01927445	Atrial Fibrillation	Not Applicable	Completed	-	Canada, Ontario ... 展开 >> Institute for Clinical Evaluative Sciences Toronto, Ontario, Canada, M4N 3M5 收起 <<
NCT03535883	-		Recruiting	June 30, 2020	United States, Connecticut ... 展开 >> Yale New Haven Hospital Recruiting New Haven, Connecticut, United States, 06510 Contact: Jonathan T Puchalski, MD,MEd 203-737-5688 jonathan.puchalski@yale.edu Contact: Zubaida L Dabre, BA, RN 203-737-5403 zubaida.dabre@yale.edu 收起 <<
NCT02921126	-		Completed	-	Italy ... 展开 >> Local Institution Ravenna, Italy, 48121 收起 <<
NCT02120560	Atrial Fibrillation ... 展开 >> Cerebrothromboembolus Neurocognitive Function 收起 <<	Phase 4	Withdrawn	July 2015	United States, California ... 展开 >> University of California, San Francisco San Francisco, California, United States, 94143 收起 <<
NCT01924065	Atrial Fibrillation ... 展开 >> Cardioversion Cerebrovascular Stroke 收起 <<	Phase 3	Active, not recruiting	December 2018	Turkey ... 展开 >> Suleyman Demirel University Isparta, Mediterranean Region, Turkey, 32260 收起 <<
NCT03124030	-		Recruiting	November 15, 2018	Italy ... 展开 >> Clinica Odontoiatrica e Stomatologica Recruiting Trieste, Italy, 34100 Contact: Roberto Di Lenarda, Prof 0403992254 ext 0039 rdilenarda@units.it Contact: Federico Berton, Dr. 0403992020 ext 0039 fberton@units.it Sub-Investigator: Roberto Rizzo, Dr. Sub-Investigator: Michele Maglione, Prof. Sub-Investigator: Fulvia Costantinides, Dr. Sub-Investigator: Erika Visintini, Dr. Principal Investigator: Roberto Di Lenarda, Prof. Sub-Investigator: Federico Berton, Dr. 收起 <<
NCT03388775	-		Recruiting	December 2018	Brazil ... 展开 >> Clinics Hospital of Faculty of Medicine of Paulista State University Recruiting Botucatu, São Paulo, Brazil, 18607621 Contact: Winston B Yoshida, MD; PhD 55 14 38116269 jvascbr.ed@gmail.com Contact: Marcone L Sobreira, MD; PhD 55 14 38116269 mlsobreira@gmail.com Sub-Investigator: Winston B Yoshida, MD; PhD Sub-Investigator: Marcone L Sobreira, MD; PhD Sub-Investigator: Regina Moura, MD; PhD Sub-Investigator: Edwaldo E Jovilliano, MD; PhD Sub-Investigator: Ana T Guillaumon, MD; PhD Sub-Investigator: Marcelo J Almeida, MD; PhD Sub-Investigator: Daniel G Miquelin Sub-Investigator: Ludvig Hafner Sub-Investigator: Martin A Geiger 收起 <<
NCT01962545	Atrial Fibrillation ... 展开 >> Coronary Artery Disease 收起 <<	Phase 4	Completed	-	Japan ... 展开 >> Kyoto University Graduate School of Medicine Kyoto, Japan, 606-8507 收起 <<
NCT03062319	Ischemic Stroke ... 展开 >> Atrial Fibrillation Atherothrombosis 收起 <<	Phase 4	Recruiting	January 31, 2021	Japan ... 展开 >> Kobe City Medical Center General Hospital Recruiting Kobe, Hyogo, Japan, 650-0047 Contact: Nobuyuki Sakai, MD 078-302-7537 n.sakai@siren.ocn.ne.jp Contact: Nobuyuki Ohara, MD 078-302-7537 nobuyuki.ohara@gmail.com National Cerebral and Cardiovascular Center Recruiting Suita, Osaka, Japan, 565-8565 Contact: Hiroshi Yamagami, MD 06-6833-5012 ext 8025 yamagami-brain@umin.ac.jp Contact: Shuhei Okazaki, MD 06-6833-5012 ext 8123 s-okazaki@umin.ac.jp 收起 <<
NCT03508258	-		Active, not recruiting	May 29, 2019	United States, Maryland ... 展开 >> Local Institution Bethesda, Maryland, United States, 20814 收起 <<
NCT03124004	-		Recruiting	November 15, 2018	Italy ... 展开 >> Clinica Odontoiatrica e Stomatologica Recruiting Trieste, Italy, 34100 Contact: Roberto Di Lenarda, Prof. 0403992254 ext 0039 rdilenarda@units.it Contact: Federico Berton, Dr. 0403992020 ext 0039 fberton@units.it Sub-Investigator: Fulvia Costantinides, Dr. Sub-Investigator: Gaetano Castronovo, Dr. 收起 <<
NCT03520868	-		Recruiting	August 4, 2019	United States, Massachusetts ... 展开 >> St Elizabeth Medical Center Recruiting Brighton, Massachusetts, United States, 02135 Contact: Michael V Orlov, MD 617-789-3000 ext 3187 michael.orlov@steward.org Contact: Wajih Syed, md 617-789-3000 ext 3109 wajih.syed@steward.org 收起 <<
NCT03108872	-		Recruiting	October 30, 2017	Korea, Republic of ... 展开 >> Sejong general hospital, 91-121 Sosa 2-Dong, Sosa-Gu Recruiting Bucheon, Gyeonggi, Korea, Republic of, 422-711 Contact: Hyun-Jong Lee, MD 82-10-6217-9315 untouchables@sejongh.co.kr 收起 <<
NCT02900170	-		Recruiting	June 2018	United States, Pennsylvania ... 展开 >> Einstein Medical Center Recruiting Philadelphia, Pennsylvania, United States, 19141 Contact: Basma Abdulhadi, MD abdulhab@einstein.edu 收起 <<
NCT02504177	Atrial Fibrillation	Not Applicable	Recruiting	June 2019	Korea, Republic of ... 展开 >> Severance Cardiovascular Hospital, Yonsei University Health System Recruiting Seoul, Korea, Republic of, 120-752 Contact: Hui-Nam Pak, M.D., Ph.D. 82-2-2228-8459 hnpak@yuhs.ac 收起 <<
NCT02279940	-		Completed	-	Canada, Alberta ... 展开 >> University of Alberta Edmonton, Alberta, Canada, T6G 2B7 收起 <<
NCT03083704	Bleeding	Phase 1	Completed	-	United States, California ... 展开 >> West Coast Clinical Trials Cypress, California, United States, 90630 收起 <<
NCT02185027	-		Unknown	December 2015	Belgium ... 展开 >> CHU Brugmann Recruiting Brussels, Belgium Contact: David Faraoni david.faraoni@huderf.be Principal Investigator: David Faraoni France CH Agen Recruiting Agen, France Contact: Albert Trinh-Duc albert.trinh-duc@wanadoo.fr Principal Investigator: Albert Trinh-Duc CHU d'Amiens Recruiting Amiens, France Contact: Marie-Antoinette Sevestre marie.sevestre@gmail.com Principal Investigator: Marie-Antoinette Sevestre CHR Annecy Recruiting Annecy, France Contact: Marie Lebouc mlebouc@ch-annecy.fr Principal Investigator: Loic Belle Sub-Investigator: Etienne Gautheron Sub-Investigator: Albrice Levrat Sub-Investigator: Frédéric Heluwaert CHU Besançon Recruiting Besançon, France Contact: Emmanuel Samain e1samain@chu-besancon.fr Principal Investigator: Emmanuel Samain CHU Bordeaux Recruiting Bordeaux, France Contact: Stephanie Roullet stephanie.roullet@chu-bordeaux.fr CH Castres Recruiting Castres, France Contact: Jean-Baptiste Rieu jb.rieu@wanadoo.fr Principal Investigator: Jean-Baptiste Rieu CH Chambéry Recruiting Chambery, France Contact: Eléna NEAGOE silvia.neagoe@ch-chambery.fr Principal Investigator: Eléna Neagoe Sub-Investigator: Catherine Chastagner CHU Clermont-Ferrand Recruiting Clermont-ferrand, France Contact: Sophie Kauffmann skauffmann@chu-clermontferrand.fr Principal Investigator: Sophie Kauffmann Sub-Investigator: Julien Pascal Sub-Investigator: Nicolas Combaret Sub-Investigator: Aurélie Fournet-Fayard Sub-Investigator: Anne-Laure Cherprenet Sub-Investigator: Aurélien Lebreton Sub-Investigator: Fares Moustafa CH Alpes leman Recruiting Contamine-sur-Arve, France Contact: Cécile Defournel cdefournel@ch-alpes-leman.fr Principal Investigator: Cécile Defournel CHU Dijon Recruiting Dijon, France Contact: Emmanuel De Maistre, MD emmanuel.demaistre@chu-dijon.fr Principal Investigator: Emmanuel De Maistre Sub-Investigator: Fabienne Volot Sub-Investigator: Claude Girard CH Gap Recruiting GAP, France Contact: Stéphane Macey stephmacey@gmail.com Principal Investigator: Stéphane Macey CHU de Grenoble Recruiting Grenoble, France, 38043 Contact: Pierre ALBALADEJO, MD, PhD PAlbaladejo@chu-grenoble.fr Contact: Pauline Romégoux PRomegoux@chu-grenoble.fr Sub-Investigator: Sébastien Thomas Sub-Investigator: Françoise Bouillet Sub-Investigator: Gilles Pernod Sub-Investigator: Carole Paquier Sub-Investigator: Raphaël Marlu Groupe Hospitalier Mutualiste Grenoble Recruiting Grenoble, France Contact: Yohann Dubois Y.DUBOIS@ghm-grenoble.fr Principal Investigator: Yohann Dubois CHRU Lille Recruiting Lille, France Contact: Sophie Susen sophie.susen@chru-lille.fr Principal Investigator: Sophie Susen Sub-Investigator: Nathalie Trillot HCL - Edouard Herriot Recruiting Lyon, France Contact: Annick Genty annick.genty@chu-lyon.fr Principal Investigator: Pierre Yves Gueugniaud Sub-Investigator: Annick Genty Sub-Investigator: Laurent Jacquin HCL - Hôpital de la Croix-Rousse Recruiting Lyon, France Contact: Frédéric Aubrun frederic.aubrun@chu-lyon.fr Principal Investigator: Frédéric Aubrun Sub-Investigator: Fédérico Bravo HCL - Lyon Sud Recruiting Lyon, France Contact: Vincent Piriou vincent.piriou@chu-lyon.fr Principal Investigator: Vincent Piriou Sub-Investigator: Jean Stéphane David Sub-Investigator: Carine Delaleu-Rague CHU Marseille Recruiting Marseille, France Contact: William Cohen william.cohen@ap-hm.fr Principal Investigator: Marc Léone Sub-Investigator: Pierre Morange Sub-Investigator: William Cohen CHU Montpellier Recruiting Montpellier, France Contact: Jean-François Schved schvedjf@aol.com Principal Investigator: Jean-François Schved Sub-Investigator: Samir Jaber Centre Emile Gallé - SINCAL Recruiting Nancy, France Contact: Sébastien Robaux srobaux@sincal-cto.fr Principal Investigator: Sébastien Robaux CHU Nancy Recruiting Nancy, France Contact: Hervé Bouaziz h.bouaziz@chu-nancy.fr Principal Investigator: Hervé Bouaziz Sub-Investigator: Gérard Audibert Sub-Investigator: Michel Heck CHU Nantes Recruiting Nantes, France Contact: Karim Asehnoune Karim.asehnoune@chu-nantes.fr Principal Investigator: Karim Asehnoune Sub-Investigator: Jerome Paulus CHU Nimes Recruiting Nimes, France Contact: Jean-Yves Lefrant jean.yves.lefrant@chu-nimes.fr Principal Investigator: Jean-Yves Lefrant CH de Niort Recruiting Niort, France Contact: Guillaume Lucas guillaume.lucas@ch-niort.fr Principal Investigator: Guillaume Lucas APHP - Antoine Beclere Recruiting Paris, France Contact: Frederic Mercier frederic.mercier@abc.aphp.fr Principal Investigator: Frederic Mercier APHP - Tenon Recruiting Paris, France Contact: Ismail Elalamy ismail.elalamy@tnn.aphp.fr Principal Investigator: Ismail Elalamy Sub-Investigator: Francis Bonnet Sub-Investigator: Chryssa Papageorgiou APHP Henri Mondor Recruiting Paris, France Contact: Catherine Matheron catherine.matheron@hmn.aphp.fr Principal Investigator: Catherine Matheron APHP Hôpital Bichat Recruiting Paris, France Contact: Dan Longrois dan.longrois@bch.aphp.fr Principal Investigator: Dan Longrois Sub-Investigator: Nadine Ajzenberg Sub-Investigator: Marie Geneviève Huisse APHP Hôpital Cochin Recruiting Paris, France Contact: Charles Marc Samama marc.samama@cch.aphp.fr Principal Investigator: Charles Marc Samama Sub-Investigator: Anne Godier Sub-Investigator: Nadia Rosencher Sub-Investigator: Claire Flaujac APHP Site St Antoine Recruiting Paris, France Contact: Marc Beaussier marc.beaussier@sat.aphp.fr Principal Investigator: Marc Beaussier Sub-Investigator: Daniel Trouslard Aphp-Hegp Recruiting Paris, France Contact: Guy Meyer guy.meyer@egp.aphp.fr Principal Investigator: Guy Meyer Sub-Investigator: Didier Journois APHP-Hôpital Beaujon Recruiting Paris, France Contact: Emmanuelle De Raucourt emmanuelle.de-raucourt@bjn.aphp.fr Principal Investigator: Emmanuelle De Raucourt Sub-Investigator: Julien Josserand Centre Hôpital Américain Recruiting Paris, France Contact: Paul Ihout Paul.IHOUT@ahparis.org Principal Investigator: Emmanuel Marret CHU Bicêtre Recruiting Paris, France Contact: Antonia Blanié blanieodri@gmail.com Principal Investigator: Dan Benhamou Sub-Investigator: Antonia Blanié CHU Rennes Recruiting Rennes, France Contact: Catherine Blery catherine.blery@chu-rennes.fr Principal Investigator: Hélène Beloeil Sub-Investigator: Catherine Blery Sub-Investigator: Lauren Daviet Sub-Investigator: Pierre Gueret CHRU Strasbourg - Hôpital Civil Recruiting Strasbourg, France Contact: Annick Steib Annick.steib@chru-strasbourg.fr Sub-Investigator: Annick Steib Hôpitaux du Léman Recruiting Thonon, France Contact: François Bouniol F-BOUNIOL@ch-hopitauxduleman.fr Principal Investigator: François Bouniol Hôpital d'Instruction des Armées Sainte-Anne Recruiting Toulon, France Contact: Eric Meaudre eric.meaudre@club-internet.fr Principal Investigator: Eric Meaudre CHU Toulouse Recruiting Toulouse, France Contact: Pierre Sié sie.p@chu-toulouse.fr Principal Investigator: Pierre Sié Sub-Investigator: Vincent Minville CH Voiron Recruiting Voiron, France Contact: Cyrille Venet venet_cyrille@yahoo.fr 收起 <<
NCT02339493	Atrial Fibrillation ... 展开 >> Stroke 收起 <<	Not Applicable	Completed	-	United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 收起 <<
NCT02657512	Healthy	Phase 1	Completed	-	France ... 展开 >> CHU de SAINT-ETIENNE Saint-etienne, France, 42000 收起 <<
NCT03490994	Acute Heart Failure	Phase 4	Not yet recruiting	January 31, 2020	-
NCT03012906	-		Recruiting	July 2019	France ... 展开 >> Assistance Publique Hopitaux de Marseille Recruiting Marseille, France, 13354 收起 <<
NCT03765242	-		Active, not recruiting	December 29, 2021	Japan ... 展开 >> Local Institution Minato-ku, Tokyo, Japan, 1080074 收起 <<

靶点	Factor Xa Factor Xa (rabbit), Ki:0.17 nM Factor Xa (human), Ki:0.08 nM
描述	Apixaban (BMS-562247-01) is a potent, selective, reversible, and orally active inhibitor of Factor Xa, displaying inhibition constants of 0.08 nM in humans and 0.17 nM in rabbits. It is currently being developed for the prevention and treatment of various thromboembolic conditions^[1]. Apixaban is applied for the prevention and treatment of various thromboembolic diseases^[2].
体内研究	Pharmacokinetically, Apixaban demonstrates low clearance (Cl: 0.02 L/kg/h) and volume of distribution (Vdss: 0.2 L/kg) in dogs, along with a moderate half-life (T1/2: 5.8 hours) and good oral bioavailability (F: 58%). This profile underscores its potential for consistent and predictable dosing in clinical settings^[1]. In various rabbit models of thrombosis—arteriovenous-shunt thrombosis (AVST), venous thrombosis (VT), and electrically mediated carotid arterial thrombosis (ECAT)—Apixaban demonstrates dose-dependent antithrombotic effects. The effective concentrations (EC50) required for these effects are 270 nM, 110 nM, and 70 nM, respectively, highlighting its efficacy in inhibiting thrombosis across different vascular contexts^[2]. Additionally, Apixaban effectively inhibits factor Xa activity with an IC50 of 0.22 μM in rabbit ex vivo, confirming its potent anti-factor Xa activity beyond human models^[3]. In chimpanzees, Apixaban also exhibits a favorable pharmacokinetic profile with a small volume of distribution (Vdss: 0.17 L/kg), low systemic clearance (Cl: 0.018 L/kg/h), and good oral bioavailability (F: 59%)^[4].
体外研究	In laboratory tests, Apixaban notably prolongs clotting times in normal human plasma; concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM are required to double the prothrombin time (PT), modified prothrombin time (mPT), activated partial thromboplastin time (APTT), and HepTest, respectively. It shows the greatest efficacy in human and rabbit plasma, while exhibiting lesser potency in rat and dog plasma in both PT and APTT assays^[2].

CAS号	503612-47-3
分子式	C₂₅H₂₅N₅O₄
分子量	459.497

别名	BMS-562247-01
运输	蓝冰

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