生物活性 | |||
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靶点 |
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描述 | Edoxaban tosylate monohydrate is an orally active, potent, selective and direct FXa inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and thrombin, and is more than 10,000-fold selective for free human FXa and thrombomodulin over other thrombin enzymes.Edoxaban tosylate monohydrate is used in thromboembolic disease prevention studies. Edoxaban tosylate monohydrate is used in studies for the prevention of thromboembolic diseases.Edoxaban tosylate monohydrate prolongs human plasma PT, TT, and APTT in a concentration-dependent manner[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.35mL 0.27mL 0.14mL |
6.77mL 1.35mL 0.68mL |
13.55mL 2.71mL 1.35mL |
参考文献 |
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