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胆固醇 /Cholesterol {[allProObj[0].p_purity_real_show]}

货号：A612467 同义名： 胆甾醇 / N-Octadecanoyl-monosialoganglioside GM1 (NH4+salt);Cholesterin

Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated.

Cholesterol 化学结构 CAS号：57-88-5
Cholesterol 化学结构
CAS号：57-88-5
Cholesterol 3D分子结构
CAS号：57-88-5
Cholesterol 化学结构 CAS号：57-88-5
Cholesterol 3D分子结构 CAS号：57-88-5
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Cholesterol 纯度/质量文件 产品仅供科研

货号：A612467 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]
• JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]
• BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]
• J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]
• PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]
更多 >

Cholesterol 生物活性

描述 Cholesterol, as a kind of the oxidizable lipids, is an agent of biomembranes and plasma lipoproteinsis. In vitro studies, cholesterol could impact the function and inhibition of multidrug resistance P-glycoprotein (Pgp) in NIH 3T3 cells , through some special substrate and cell-type-specific manners. In vivo studies, it was found that dietary cholesterol could increase plasma lipoprotein concentrations in adult baboons, as well as suppress the activity of hepatic sterol 27-hydroxylase in baboons. Besides this, maternal cholesterol could also strengthen the movement of cholesterol down a concentration gradient in the placenta , lipoprotein secretion from the yolk sac (shown previously) and possibly placental NPC1L1 expression in the golden Syrian hamster.

Cholesterol 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01156597 - Completed - -
NCT02534376 Prostate Cancer Early Phase 1 Recruiting February 2020 United States, California ... 展开 >> Cedars Sinai Medical Center Recruiting Los Angeles, California, United States, 90048 Contact: Jenny Park, MPH    310-423-8762    jenny.park@cshs.org    Principal Investigator: Hyung L Kim, MD 收起 <<
NCT01156597 Type 2 Diabetes Mellitus Phase 3 Completed - United States, Florida ... 展开 >> Diabetes Research Institute Miami, Florida, United States, 33136 收起 <<

Cholesterol 参考文献

[1]Terao J. Cholesterol hydroperoxides and their degradation mechanism. Subcell Biochem. 2014.

[2]Luker GD, Pica CM, et al. Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains. Biochemistry. 2000;39(26):7651-61.

[3]Mott GE, Jackson EM, et al. Dietary cholesterol and type of fat differentially affect cholesterol metabolism and atherosclerosis in baboons. J Nutr. 1992;122(7):1397-406.

[4]Kushwaha RS, Guntupalli B, et al. Effect of dietary cholesterol and fat on the expression of hepatic sterol 27-hydroxylase and other hepatic cholesterol-responsive genes in baboons (Papio species). Arterioscler Thromb Vasc Biol. 1995;15(9):1404-11.

[5]Burke KT, Colvin PL, et al. Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster. J Lipid Res. 2009;50(6):1146-55.

Cholesterol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.93mL

2.59mL

1.29mL

25.86mL

5.17mL

2.59mL

Cholesterol 技术信息

CAS号57-88-5
分子式C27H46O
分子量 386.654
别名 胆甾醇 ;N-Octadecanoyl-monosialoganglioside GM1 (NH4+salt);Cholesterin;NSC 8798;HSDB 7106;CCRIS2834 CCRIS-2834;AI3 03112 CCRIS 2834;AI3-03112;N-Stearoyl GM1;N-C18:0 GM1
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Store in freezer, under -20°C
溶解度

无水乙醇: 20 mg/mL(51.73 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇
动物实验配方

Tags: Cholesterol | N-Octadecanoyl-monosialoganglioside GM1 (NH4+salt);Cholesterin;NSC 8798;HSDB 7106;CCRIS2834 CCRIS-2834;AI3 03112 CCRIS 2834;AI3-03112;N-Stearoyl GM1;N-C18:0 GM1 | 胆甾醇 | Additive and Auxiliary Reagent | Medicinal Excipient | Plant Standard | Cholestane | AmBeed-信号通路专用抑制剂 | Cholesterol 纯度/质量文件 | Cholesterol 生物活性 | Cholesterol 临床数据 | Cholesterol 参考文献 | Cholesterol 实验方案 | Cholesterol 技术信息

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