Bleomycin Sulfate is a glycopeptide antitumor antibiotic with antineoplastic efficacy[1].
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Bleomycin Sulfate is a glycopeptide antitumor antibiotic with antineoplastic efficacy[1]. Bleomycin sulfate treatment (3.5-4.0 mg/kg; intra-tracheal) on day 0, body weights decrease by day 4 then increases by Day 7 through the end of the study. Intra-tracheal bleomycin produced a statistically significant increase in lung hydroxyproline levels as well as increase in right caudal lung lobe mass[2]. Bleomycin sulfate (intratracheally; 2.5 mg/kg; 1.25 mg/ml, approximately 50 µl per mouse) induces pulmonary fibrosis in male C57BL/6 mice (8 weeks old, average weight approximately 24.5 g) [3].
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