货号:A142721
同义名:
抗坏血酸棕榈酸酯
/ L-Ascorbic acid 6-hexadecanoate;6-O-Palmitoyl-L-ascorbic acid
Ascorbyl palmitate是由抗坏血酸与棕榈酸形成的酯,创造出一种脂溶性的维生素 C,亦作为抗氧化剂食品添加剂使用。
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描述 | Ascorbyl palmitate (AP) is a fatty acid ester endowed with antioxidant properties, used as a food additive and cosmetic ingredient, which is presently produced by chemical synthesis[3]. Ascorbyl palmitate can interact with amylose to form amylose-lipid complexes. About 93% and 66% of ascorbyl palmitate were encapsulated when 15mg and 50mg was respectively added to maize starch during pasting[4]. The growth of HUVECs (Human Umbilical Vein Endothelial Cells)was decreased upon treatment with AP in dose-and time-dependent manner. Furthermore, real time PCR results showed that AP induces apoptosis by up-regulation of caspase-3, 9 and down-regulation of Bcl-2 ratio[5]. Ascorbyl palmitate (AP) and sodium ascorbyl phosphate (SAP) supplementations to skin proved a promising choice for controlling facial sebum secretions and could be evaluated for undesired oily skin and acne reductions for beautifying the facial appearance[6]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT01066182 | Learning Beha... 展开 >>viour 收起 << | Phase 2 | Completed | - | United Kingdom ... 展开 >> Department of Social Policy and Social Work Oxford, Oxfordshire, United Kingdom, OX1 2ER 收起 << |
NCT03201588 | Ophthalmological Disorder | Not Applicable | Recruiting | December 31, 2019 | Sweden ... 展开 >> Queen Silvias Childrens Hospital Recruiting Göteborg, Sweden, 41650 Contact: Karin Savman, MD,PhD +46 ext 739940937 karin.savman@vgregion.se Contact: Svetlana Najm, MD +46 ext 738999992 svatlana.najm@vgregion.se Skanes Universitetssjukhus Recruiting Lund, Sweden Contact: David Ley, Professor +46 ext 709264824 david.ley@med.lu.se Contact: Ingrid Pupp, MD,PhD +46 ext 761712021 ingrid.pupp@med.lu.se KI Recruiting Stockholm, Sweden, 14157 Contact: Boubou Hallberg, MD.PhD +46 ext 700021010 boubou.hallberg@karolinska.se Contact: Dirk Wackernagel, MD +46 ext 700011758 dirk.wackernagel@karolinska.se 收起 << |
NCT01192269 | Healthy | Not Applicable | Completed | - | Germany ... 展开 >> Ludwig Maximilians University Munich, Germany, 80337 收起 << |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.41mL 0.48mL 0.24mL |
12.06mL 2.41mL 1.21mL |
24.12mL 4.82mL 2.41mL |
CAS号 | 137-66-6 |
分子式 | C22H38O7 |
分子量 | 414.53 |
别名 | 抗坏血酸棕榈酸酯 ;L-Ascorbic acid 6-hexadecanoate;6-O-Palmitoyl-L-ascorbic acid;HSDB 418;CCRIS 3930;BRN 0096552;6-Palmitoylascorbic acid;Vitamin C palmitate;NSC 402451;Ascorbylpalmitic Acid |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry,Room Temperature |
溶解方案 |
DMSO: 105 mg/mL(253.3 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |