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6-Demethoxytangeretin
6-去甲氧基三苯甲基黄嘌呤 /6-Demethoxytangeretin
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货号：A958074
6-Demethoxytangeretin is a natural product isolated and purified from the herbs of Andrographis paniculata with anti-inflammatory activity.
6-Demethoxytangeretin 化学结构
6-Demethoxytangeretin 3D分子结构
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6-Demethoxytangeretin 纯度/质量文件 产品仅供科研
货号：A958074
标准纯度：
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产品说明书
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6-Demethoxytangeretin 质控信息
ASP3026
+
99%+
ALK-IN-1
++++
98+%
Crizotinib
++++
ALK, IC50: 24 nM
ROS1, Ki: <0.025 nM
98%
Entrectinib
✔
99%+
Brigatinib
+++
ROS1, IC50: 1.9 nM
ALK, IC50: 0.37 nM
FLT3
98%
NVP-TAE 684
+
99%+
Alectinib
++
ALK (F1174L), IC50: 3.5 nM
ALK, IC50: 1.9 nM
98%
Ceritinib
+++
IGF-1R,Insulin Receptor
98%
GSK1838705A
+++
IGF-1R,Insulin Receptor
99%
AZD-3463
++
IGF-1R
99%
Lorlatinib
++++
ALK (L1196M), Ki: 0.07 nM
ROS1, Ki: <0.07 nM
98%
Repotrectinib
+
ALK(G1202R), IC50: 1.26 nM
ALK(L1196M), IC50: 1.01 nM
Src
99%
Belizatinib
++
99%+
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
6-Demethoxytangeretin 生物活性
描述
6-Demethoxytangeretin is a natural product isolated and purified from the herbs of Andrographis paniculata with anti-inflammatory activity. It also can suppress production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase and mitogen-activated protein kinase pathways and suppress the interleukin 1 (IL-1) induced production of proMMP-9/progelatinase B in rabbit synovial cells in a dose dependent manner (< 64 mM).
6-Demethoxytangeretin 参考文献
6-Demethoxytangeretin 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.92mL
0.58mL
0.29mL
14.61mL
2.92mL
1.46mL
29.21mL
5.84mL
2.92mL
6-Demethoxytangeretin 技术信息
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