GBR 12935 二盐酸盐 /GBR 12935 2HCl
{[allProObj[0].p_purity_real_show]}
货号：A751627
同义名：
GBR 12935 (hydrochloride);GBR 12935 dihydrochloride
GBR 12935 2HCl is a potent and selective dopamine reuptake inhibitor with KD of 5.5 nM in rat striatal membranes.
GBR 12935 2HCl 化学结构
GBR 12935 2HCl 3D分子结构
规格
价格
会员价
库存
数量
{[ item.pr_size ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}
{[ getRatePrice(item.pr_rmb_sale, 1,1) ]}
{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}
{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]}
{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb_sale, 1,1) ]}
{[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]}
{[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]}
现货
咨询
-
+
GBR 12935 2HCl 纯度/质量文件 产品仅供科研
货号：A751627
标准纯度：
{[allProObj[0].p_purity_real_show]}
产品说明书
全球学术期刊中引用的产品
• Nat. Biomed. Eng. , 2024, 8, 1412-1424. Ambeed. A538667 ,
A631746
]
• JMC , 2024. Ambeed. A356070
]
• BMC Cancer , 2024, 24(1): 1415. Ambeed. A209020
]
• J. Am. Soc. Mass Spectrom. , 2024, 35(12): 3192-3202. Ambeed. A961334 ,
A292945 ,
A230770 ,
A300620 ,
A1114580 ,
A1159765 ,
A206238
]
• PloS One , 2024, 19(11): e0308060. Ambeed. 更多 >
GBR 12935 2HCl 质控信息
GBR 12935 2HCl 生物活性
描述
GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor. The calculated Kd of [3H]GBR-12935 binding to CYP2D6 was 42.2 nM[3] [4] [5]
GBR 12935 2HCl 参考文献
[1] Rahman S, Engleman E, et al. Negative interaction of dopamine D2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens. Eur J Pharmacol. 2001 Feb 23;414(1):37-44.
[2] Hiroi T, Imaoka S, et al. Specific binding of 1-[2-(diphenylmethoxy)ethyl] -4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. Biochem Pharmacol. 1997 Jun 15;53(12):1937-9.
[3] Hiroi T, Imaoka S, Chow T, Yabusaki Y, Funae Y. Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. Biochem Pharmacol. 1997 Jun 15;53(12):1937-9
[4] Rahman S, Engleman E, Simon J, McBride WJ. Negative interaction of dopamine D2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens. Eur J Pharmacol. 2001 Feb 23;414(1):37-44
[5] Tolliver BK, Carney JM. Comparison of cocaine and GBR 12935: effects on locomotor activity and stereotypy in two inbred mouse strains. Pharmacol Biochem Behav. 1994 Jul;48(3):733-9
展开
GBR 12935 2HCl 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.05mL
0.41mL
0.21mL
10.26mL
2.05mL
1.03mL
20.51mL
4.10mL
2.05mL
GBR 12935 2HCl 技术信息
搜索
