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全部(123) Modulator(2) Agonist(4) Antagonist(22) Inhibitor(6)
Azilsartan medoxomil is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
Azilsartan is an orally available angiotensin II type 1 (AT1) receptor antagonist with IC50 value of 2.6 nM.
PD123319 Ditrifluoroacetate is a potent, selective and non-peptide angiotensin AT2 receptor antagonist.
Candesartan-d4是 Candesartan 的氘代形式,常用于研究药代动力学和药物代谢。Candesartan是一种临床用于治疗高血压和心力衰竭的药物,通过阻断血管紧张素II与其AT1受体结合,抑制血管收缩和盐水潴留,进而降低血压,涉及RAAS(肾素-血管紧张素-醛固酮系统)通路的调节。
Olmesartan-d4是 Olmesartan 的氘代形式,通常用于药物代谢和药代动力学研究。Olmesartan是一种血管紧张素II受体拮抗剂(ARB),其主要作用是通过阻断血管紧张素II与其AT1受体的结合,抑制血管收缩和醛固酮的分泌,从而降低血压并减轻心脏负担。
Losartan-d4 (carboxylic acid)是一种氘代 Losartan,主要用于研究 Losartan 在药物代谢和药理学中的应用,尤其适用于高血压和心血管疾病相关研究。
Sparsentan是一种双重拮抗剂,能够同时作用于血管紧张素 II (angiotensin II) 和内皮素 A (endothelin A) 受体,具有在高血压和心血管疾病治疗中的应用潜力。
AT2R agonist C21 is a small-molecule ATR receptor (AT2R) agonist.
Tranilast is an antiallergic agent.
Olmesartan Medoxomil is a synthetic imidazole-derived angiotensin II receptor antagonist, acting as a prodrug with an antihypertensive property.
Olmesartan medoxomil impurity C是 Olmesartan medoxomil 的杂质,后者是一种有效的、选择性的血管紧张素 AT1 受体抑制剂,IC50 为 66.2 μM。
Fimasartan is an improved non-peptide angiotensin II receptor blocker used for the treatment of hypertension and heart failure, which enables higher potency and longer duration than losartan.
Eprosartan Mesylate is a reversible and competitive angiotensin II receptor inhibitor.
Losartan D4 is deuterium labeled Losartan, which is an angiotensin II receptor antagonist.
Candesartan is a benzimidazole-derived and competitive AT1 inhibitor with IC50 value of 0.26 nM.
Losartan potassium (DuP-753 potassium) 作为血管紧张素II受体1型(AT1)拮抗剂,竞争性抑制血管紧张素II与AT1的结合,IC50为20 nM。
Losartan是一种血管紧张素 II 受体拮抗剂,以 IC50 为 20 nM 竞争性抑制血管紧张素 II 与 AT1 受体结合。
Angiotensin II (3-8), human is an agonist of angiotensin AT1 receptor. Its activation is relatively weak.
AVE 0991 is a nonpeptide Ang-(1-7) receptor Mas agonist.
trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
Tags: 血管紧张素受体 | Angiotensin Receptor | G蛋白偶联受体/G蛋白 | GPCR/G Protein | 血管紧张素受体 相关产品
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