Azilsartan medoxomil is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.

Candesartan-d4是 Candesartan 的氘代形式，常用于研究药代动力学和药物代谢。Candesartan是一种临床用于治疗高血压和心力衰竭的药物，通过阻断血管紧张素II与其AT1受体结合，抑制血管收缩和盐水潴留，进而降低血压，涉及RAAS（肾素-血管紧张素-醛固酮系统）通路的调节。

Olmesartan-d4是 Olmesartan 的氘代形式，通常用于药物代谢和药代动力学研究。Olmesartan是一种血管紧张素II受体拮抗剂（ARB），其主要作用是通过阻断血管紧张素II与其AT1受体的结合，抑制血管收缩和醛固酮的分泌，从而降低血压并减轻心脏负担。

Losartan-d4 (carboxylic acid)是一种氘代 Losartan，主要用于研究 Losartan 在药物代谢和药理学中的应用，尤其适用于高血压和心血管疾病相关研究。

Sparsentan是一种双重拮抗剂，能够同时作用于血管紧张素 II (angiotensin II) 和内皮素 A (endothelin A) 受体，具有在高血压和心血管疾病治疗中的应用潜力。

AT2R agonist C21 is a small-molecule ATR receptor (AT2R) agonist.

Tranilast is an antiallergic agent.

Olmesartan Medoxomil is a synthetic imidazole-derived angiotensin II receptor antagonist, acting as a prodrug with an antihypertensive property.

Olmesartan medoxomil impurity C是 Olmesartan medoxomil 的杂质，后者是一种有效的、选择性的血管紧张素 AT1 受体抑制剂，IC50 为 66.2 μM。

Fimasartan is an improved non-peptide angiotensin II receptor blocker used for the treatment of hypertension and heart failure, which enables higher potency and longer duration than losartan.

Eprosartan Mesylate is a reversible and competitive angiotensin II receptor inhibitor.

Losartan D4 is deuterium labeled Losartan, which is an angiotensin II receptor antagonist.

Candesartan is a benzimidazole-derived and competitive AT1 inhibitor with IC50 value of 0.26 nM.

Losartan potassium (DuP-753 potassium) 作为血管紧张素II受体1型（AT1）拮抗剂，竞争性抑制血管紧张素II与AT1的结合，IC50为20 nM。

Losartan是一种血管紧张素 II 受体拮抗剂，以 IC50 为 20 nM 竞争性抑制血管紧张素 II 与 AT1 受体结合。

Angiotensin II (3-8), human is an agonist of angiotensin AT1 receptor. Its activation is relatively weak.

AVE 0991 is a nonpeptide Ang-(1-7) receptor Mas agonist.

trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

Azilsartan is an orally available angiotensin II type 1 (AT1) receptor antagonist with IC50 value of 2.6 nM.

AHU-377 and valsartan can compose LCZ696 in a 1:1 molar ratio. It also works as an inhibitor of neprilysin with IC50 value of 5 nM.