Ketanserin is a specific 5-HT2A serotonin receptor antagonist with K_i of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug.

Asenapine Maleate is a 5-HT and dopamine D2 receptor antagonist used to treat schizophrenia and bipolar mania.

Risperidone is a multiple-target antipsychotic with high affinity for 5-HT2A and D2 receptors, alpha 1, alpha 2 and H1 receptors.

Blonanserin is a D2/5-HT2 receptor antagonist, atypical antipsychotic.

BMY 7378 2HCl is a 5-HT1A partial agonist and a high-affinity α1D adrenoceptor antagonist with Ki values of 2, 800 and 600 nM for cloned rat α1D, rat α1A and hamster α1B receptors respectively.

Sarpogrelate HCl is an antagonist of both 5HT2A and 5-HT2B receptors, which can block serotonin-induced platelet aggregation and treat diabetes mellitus, Buerger's disease, Raynaud's disease, coronary artery disease, angina pectoris and atherosclerosis.

Cyproheptadine Hydrochloride Sesquihydrate is a serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.

Pimavanserin Dihydroxysuccinate(2:1) is an antagonist of 5-HT2 receptor, used to treat hallucinations and psychosis in patients with Parkinson disease.

Olanzapine is a multiple-target antagonist for 5-HT2A receptors and D2 dopamine receptors, as well as muscarinic M3 receptor.

Clozapine, an antipsychotic drug, is antagonist of dopamine and other receptors used to treat schizophrenia with a Ki value of 9.5 nM for M1 receptor.

Agomelatine is a melatonin structurely similar 5-HT2C receptor antagonist as well as a potent melatonin receptor agonist, used to treat major depressive disorder.

Cyclobenzaprine HCl is a 5-HT2 receptor antagonist as a skeletal muscle relaxant and a central nervous system (CNS) depressant with elimination half-life of ‎32 hours.

RS 127445 is a potent and selective antagonist at 5-HT2B receptor with pKi value of 9.5.

Loxapine succinate salt is an multiple-target antagonist of both D2/D4 dopamine receptor and 5-HT2A/2B, 5-H7 serotonin receptor, used as an antipsychotic agent.

PRX-08066 maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model.

Flibanserin is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. It is also a P-Glycoprotein Inhibitor.