VEGFR

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VEGFR 相关产品
VEGFR 亚型比较

全部(357) Inhibitor(46)

货号			产品名	纯度
A297529	现货	促	SU5208 SU5208 is an analogue of SU5025.	99%+
A142950	现货	促	Sunitinib Malate/苹果酸舒尼替尼 Sunitinib Malate（SU 11248 Malate）是一种多靶点受体酪氨酸激酶抑制剂，对VEGFR2和PDGFRβ的IC50值分别为80 nM和2 nM。作为一种ATP竞争性抑制剂，马来酸舒尼替尼有效抑制Ire1α的自磷酸化及随后的RNase激活。	98%
A1229398	现货	促	VEGFR-2-IN-37 VEGFR-2-IN-37是一种 VEGFR-2 抑制剂，200 μM 时的抑制率约为 56.9%，可抑制人脐静脉内皮细胞 (HUVEC) 的增殖。	99%+
A1370275	现货	促	hVEGF-IN-2 hVEGF-IN-2是一种选择性 VEGF (Flk-1) 受体酪氨酸激酶抑制剂，IC₅₀ 为 2.5 μM，显示出抑制血管生成的潜力，可用于癌症及相关的血管生成疾病研究。	97%
A1598849	现货	促	VEGFR2-IN-2 VEGFR2-IN-2是一种有效的 VEGFR2 抑制剂，能够显著抑制 VEGFR2 催化活性。它在抗肿瘤和抗血管生成治疗中具有重要的研究价值。	95%
A240857	现货	促	VEGFR-2-IN-29 VEGFR-2-IN-29是一种 VEGFR-2 抑制剂，其 IC50 值为 16.5 nM。	97%
A204345	现货	促	VEGFR-IN-1 VEGFR-IN-1是一种高效的血管生成抑制剂，能够抑制 KDR、Flt-1、c-Kit、EGF-R 和 c-Src，IC₅₀ 分别为 0.02、0.18、0.24、7.3 和 7 µM，适用于与血管生成相关的癌症及其他疾病的研究。	98%+
A1461903	现货	促	Chiauranib Chiauranib是一种口服有效的多靶点抑制剂，主要靶向血管生成相关激酶如VEGFR和PDGFR。它对癌症具有强大的抗肿瘤活性，并在血管生成抑制研究中具有潜力。	97%
A708891	现货	促	hVEGF-IN-1 hVEGF-IN-1是一种选择性 VEGF 抑制剂，能有效阻断 VEGF 信号通路。它在抗癌治疗中具有潜在应用，特别是在抑制肿瘤血管生成方面。	98%
A1145666	现货	促	ZD-4190 ZD-4190 is an inhibitor of vascular endothelial cell growth factor receptor 2 (VEGFR2) and epidermal growth factor receptor (EGFR) signalling.	98%
A1174764	现货	促	Bevacizumab/贝伐珠单抗 Bevacizumab 是一种人源化的 IgG1 单克隆抗体，能够高亲和力且特异性地与所有 VEGF-A 结合。	~25mg/mL
A432321	现货	促	4,4′-Bis(4-aminophenoxy)biphenyl/4,4'-双(4-氨苯氧基)联 4,4'-Bis(4-aminophenoxy)biphenyl is a potent Flk-1 (VEGFR2) inhibitor.	98%
A694724	现货	促	BFH772 BFH772 selectively targets VEGFR2 kinase with IC50 of 3 nM.	98%
A1463355	现货	促	Zanzalintinib XL-092 is an ATP-competitive inhibitor of multiple receptor tyrosine kinases including MET, VEGFR2, AXL and MER, with IC50 values of 15, 1.6, 3.4, and 7.2 nM, respectively, in cell-based assays.	99%+
A652756	现货	促	ZM323881 HCl ZZZM 323881 HCl is a potent and selective VEGFR2 inhibitor with IC50 of < 2 nM, almost no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.	98%
A425715	现货	促	SU5205 Su5205 是一种 VEGFR2 抑制剂。	97%
A147248	现货	促	Oglufanide/奥谷法奈 Oglufanide is inhibitor of vascular endothelial growth factor (VEGF) that suppresses angiogenesis.	98%
A657558	现货	促	SU1498 SU1498 is a selective inhibitor of the VEGFR2 with IC50 of 700 nM.	99%+
A147165	现货	促	Rivoceranib Mesylate/甲磺酸阿帕替尼 Apatinib Mesylate is a VEGFR2 inhibitor with IC50 of 1 nM and also can suppress the activities of Ret (IC50 = 13 nM), c-Kit (IC50 = 429 nM) and c-Src (IC50 = 530 nM).	98+%
A394842	现货	促	Vatalanib/瓦他拉尼碱 Vatalanib is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, showing less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4.	99%+

产品名	VEGFR1 ↓ ↑	VEGFR2 ↓ ↑	VEGFR3 ↓ ↑	其他靶点	纯度
Motesanib Diphosphate	++++ VEGFR1, IC50: 2 nM	++++ VEGFR2/Flk1, IC50: 3 nM VEGFR2, IC50: 3 nM	+++ VEGFR3, IC50: 6 nM	PDGFR,RET	98%
Tivozanib	++ VEGFR1, IC50: 30 nM	+++ VEGFR2, IC50: 6.5 nM	++ VEGFR3, IC50: 15 nM		99%+
Brivanib	+ VEGFR1, IC50: 380 nM	++ Flk1, IC50: 25 nM VEGFR2, IC50: 25 nM			99%+
Regorafenib	+++ VEGFR1, IC50: 13 nM	+++ VEGFR2, IC50: 4.2 nM	+ VEGFR3, IC50: 46 nM	RET	98%
Pazopanib	+++ VEGFR1, IC50: 10 nM	++ VEGFR2, IC50: 30 nM	+ VEGFR3, IC50: 47 nM	c-Kit,FGFR,PDGFR	99%
Sitravatinib	+++ VEGFR1 (FLT1), IC50: 6 nM	+++ VEGFR2 (KDR), IC50: 5 nM	++++ VEGFR3 (FLT4), IC50: 2 nM		99%+
Foretinib	+++ VEGFR1/FLT1, IC50: 6.8 nM	++++ KDR, IC50: 0.86 nM	++++ VEGFR3/FLT4, IC50: 2.8 nM	Tie-2	99%+
MGCD-265 analog	++++ VEGFR1, IC50: 3 nM	++++ VEGFR2, IC50: 3 nM	++++ VEGFR3, IC50: 4 nM	Tie-2	99%+
Lactate	+++ VEGFR1/FLT1, IC50: 10 nM	+++ VEGFR2/Flk1, IC50: 13 nM	+++ VEGFR3/FLT4, IC50: 8 nM	c-Kit,FLT3	85%
AEE788	+ FLT1, IC50: 59 nM	+ KDR, IC50: 77 nM		EGFR	98+%
Linifanib	++++ VEGFR1/FLT1, IC50: 3 nM	++++ VEGFR2/KDR, IC50: 4 nM	+ VEGFR3/FLT4, IC50: 190 nM	FLT3	99%+
Vatalanib 2HCl	+ VEGFR1/FLT1, IC50: 77 nM	++ VEGFR2/KDR, IC50: 37 nM VEGFR2/Flk1, IC50: 270 nM	+ VEGFR3/FLT4, IC50: 660 nM	c-Kit,c-Fms	99%+
Axitinib	++++ VEGFR1/FLT1, IC50: 0.1 nM	++++ VEGFR2/KDR, IC50: 0.2 nM VEGFR2/Flk1, IC50: 0.18 nM			98%
Dovitinib	+++ VEGFR1/FLT1, IC50: 10 nM	+++ VEGFR2/Flk1, IC50: 13 nM	+++ VEGFR3/FLT4, IC50: 8 nM	c-Kit,FLT3	99%+
ZM 306416	+ VEGFR1, IC50: 0.33 μM			Src	99%+
KRN-633	+ VEGFR1, IC50: 170 nM	+ VEGFR2, IC50: 160 nM	+ VEGFR3, IC50: 125 nM	c-Kit,BTK	98%
OSI-930	+++ FLT1, IC50: 8 nM	+++ KDR, IC50: 9 nM			99%+
Lenvatinib	++ VEGFR1/FLT1, IC50: 22 nM	++++ VEGFR2/KDR, IC50: 4.0 nM	+++ VEGFR3/FLT4, IC50: 5.2 nM		98%
NVP-BAW2881	+ hVEGFR1, IC50: 820 nM	+++ hVEGFR2, IC50: 9 nM mVEGF2, IC50: 165 nM	+ hVEGFR3, IC50: 420 nM		98%
Cediranib	+++ VEGFR1/FLT1, IC50: 5 nM	++++ VEGFR2/KDR, IC50: 0.5 nM		c-Kit	99%+
Nintedanib	++ VEGFR1, IC50: 34 nM	+++ VEGFR2, IC50: 13 nM	+++ VEGFR3, IC50: 13 nM	FLT3	99+%
BMS-794833		++ VEGFR2, IC50: 15 nM			99%+
SKLB1002		++ VEGFR2, IC50: 32 nM			98%
Cabozantinib S-malate		++++ VEGFR2/KDR, IC50: 0.035 nM			99+%
Ki8751		++++ VEGFR2, IC50: 0.9 nM		c-Kit	98+%
SU 5402		++ VEGFR2, IC50: 20 nM			98%
Rivoceranib Mesylate		++++ VEGFR2, IC50: 1 nM		RET	98+%
Ponatinib		++++ VEGFR2, IC50: 1.5 nM			98%
LY2874455		+++ VEGFR2, IC50: 7 nM			99%+
ZM323881 HCl		++++ VEGFR2, IC50: <2 nM			98%
AZD2932		+++ VEGFR-2, IC50: 8 nM		c-Kit	98%
Cabozantinib		++++ VEGFR2/KDR, IC50: 0.035 nM			98%
Sorafenib		++ VEGFR2/Flk1, IC50: 90 nM VEGFR2, IC50: 90 nM			99%
CYC-116		++ VEGFR2, Ki: 44 nM		FLT3	99%+
Golvatinib		++ VEGFR2, IC50: 16 nM			99%+
Sunitinib		+ VEGFR2 , IC50: 80 nM		FLT3	98%
RAF265		++ VEGFR2, EC50: 30 nM			99%+
PD173074					99%+
BFH772		++++ VEGFR2, IC50: 3 nM			98%
Semaxinib		+ VEGFR2/Flk1, IC50: 1.23 μM			98%
Vandetanib		++ VEGFR2, IC50: 40 nM	+ VEGFR3, IC50: 110 nM	EGFR	98%
SAR131675			++ VEGFR3, IC50: 23 nM		99%+
ENMD-2076		+ VEGFR2/KDR, IC50: 58.2 nM	++ VEGFR3/FLT4, IC50: 15.9 nM	FLT3,RET	98%
Telatinib		+++ VEGFR2, IC50: 6 nM	++++ VEGFR3, IC50: 4 nM	c-Kit	99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

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