货号:A145318 同义名: 2-Butenedioic acid;Trans-Butenedioic acid
Fumaric acid a reversible inhibitor of tyrosinase.
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产品名称 | diphenolase ↓ ↑ | monophenolase ↓ ↑ | tyrosinase ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hexylresorcinol |
+++
diphenolase, IC50: 0.85 μM |
++
monophenolase, IC50: 1.24 μM |
+++
diphenolase, IC50: 0.85 μM monophenolase, IC50: 0.85 μM |
99%+ | |||||||||||||||
Aloin | ✔ | 98% | |||||||||||||||||
Arbutin |
+
tyrosinase, IC50: 1.09 mM |
98% | |||||||||||||||||
Monobenzone | ✔ | 98% | |||||||||||||||||
Deoxyarbutin |
++++
tyrosinase, IC50: 50 nM |
98% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Fumaric acid (FA), a metabolic intermediate, has been identified as an important carbohydrate derived platform chemical. Fumaric acid as a four-carbon unsaturated dicarboxylic acid is widely used in the food and chemical industries[1]. Fumaric acid is a naturally occurring organic acid that is an intermediate of the tricarboxylic acid cycle. Fungal species belonging to Rhizopus have traditionally been employed for the production of fumaric acid[2]. Fumaric acid concentrations increase with plant age and light intensity in Arabidopsis leaves. Moreover, Arabidopsis phloem exudates contain significant quantities of fumaric acid, raising the possibility that fumaric acid may function in carbon transport[3]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
8.62mL 1.72mL 0.86mL |
43.08mL 8.62mL 4.31mL |
86.15mL 17.23mL 8.62mL |
CAS号 | 110-17-8 |
分子式 | C4H4O4 |
分子量 | 116.072 |
别名 | 2-Butenedioic acid;Trans-Butenedioic acid;Tumaric acid;Kyselina fumarova;Fumarate;Lichenic acid;Donitic acid;Boletic acid;Allomaleic acid |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,Room Temperature |
溶解度 |
DMSO: 25 mg/mL(215.38 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 10 mg/mL(86.15 mM),配合低频超声助溶 |
动物实验配方 |