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反丁烯二酸 /Fumaric acid 99+%

货号:A145318 同义名: 2-Butenedioic acid;Trans-Butenedioic acid Ambeed 开学季,买赠积分,赢豪礼

Fumaric acid a reversible inhibitor of tyrosinase.

Fumaric acid 化学结构 CAS号:110-17-8
Fumaric acid 化学结构
CAS号:110-17-8
Fumaric acid 3D分子结构
CAS号:110-17-8
Fumaric acid 化学结构 CAS号:110-17-8
Fumaric acid 3D分子结构 CAS号:110-17-8
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Fumaric acid 纯度/质量文件 产品仅供科研

货号:A145318 标准纯度: 99+%
批次查询: 批次纯度:

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产品名称 diphenolase monophenolase tyrosinase 其他靶点 纯度
Hexylresorcinol +++

diphenolase, IC50: 0.85 μM

++

monophenolase, IC50: 1.24 μM

+++

diphenolase, IC50: 0.85 μM

monophenolase, IC50: 0.85 μM

99%+
Aloin 98%
Arbutin +

tyrosinase, IC50: 1.09 mM

99%+
Monobenzone 98%
Deoxyarbutin ++++

tyrosinase, IC50: 50 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Fumaric acid 生物活性

描述 Fumaric acid (FA), a metabolic intermediate, has been identified as an important carbohydrate derived platform chemical. Fumaric acid as a four-carbon unsaturated dicarboxylic acid is widely used in the food and chemical industries[1]. Fumaric acid is a naturally occurring organic acid that is an intermediate of the tricarboxylic acid cycle. Fungal species belonging to Rhizopus have traditionally been employed for the production of fumaric acid[2]. Fumaric acid concentrations increase with plant age and light intensity in Arabidopsis leaves. Moreover, Arabidopsis phloem exudates contain significant quantities of fumaric acid, raising the possibility that fumaric acid may function in carbon transport[3].

Fumaric acid 参考文献

[1]Liu H, Ma J, Wang M, Wang W, Deng L, Nie K, Yue X, Wang F, Tan T. Food Waste Fermentation to Fumaric Acid by Rhizopus arrhizus RH7-13. Appl Biochem Biotechnol. 2016 Dec;180(8):1524-1533

[2]Song CW, Kim DI, Choi S, Jang JW, Lee SY. Metabolic engineering of Escherichia coli for the production of fumaric acid. Biotechnol Bioeng. 2013 Jul;110(7):2025-34

[3]Chia DW, Yoder TJ, Reiter WD, Gibson SI. Fumaric acid: an overlooked form of fixed carbon in Arabidopsis and other plant species. Planta. 2000 Oct;211(5):743-51

Fumaric acid 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

8.62mL

1.72mL

0.86mL

43.08mL

8.62mL

4.31mL

86.15mL

17.23mL

8.62mL

Fumaric acid 技术信息

CAS号110-17-8
分子式C4H4O4
分子量 116.072
别名 2-Butenedioic acid;Trans-Butenedioic acid;Tumaric acid;Kyselina fumarova;Fumarate;Lichenic acid;Donitic acid;Boletic acid;Allomaleic acid
运输蓝冰
存储条件

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度

DMSO: 25 mg/mL(215.38 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 10 mg/mL(86.15 mM),配合低频超声助溶

动物实验配方
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