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全部(43) Inhibitor(3)
LY2584702 tosylate salt is an inhibitor of p70S6K signaling and can prevent the phosphorylation of S6 subunit of ribosomes.
LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and RSK3, respectively.
S6K1-IN-DG2是一种 p70S6K 抑制剂,IC50 小于 100 nM,适用于细胞增殖和信号转导通路的研究,特别是在与 mTOR 通路相关的研究中具有应用潜力。
S6K1-IN-1是一种选择性p70S6K1抑制剂,能够有效抑制这一关键的信号通路成分。它在细胞增殖和癌症研究中表现出重要作用。
PF-4708671是一种强效、细胞可渗透的 S6K1 抑制剂,Ki 为 20 nM,IC50 为 160 nM。
LY2584702 is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
BI-D1870是一种ATP竞争性的、细胞渗透的、能够穿透大脑的RSK同工型抑制剂,其对RSK1、RSK2、RSK3和RSK4的IC50值分别为31 nM、24 nM、18 nM和15 nM。
Carnosol, a natural product isolated and purified from the herbs of Rosmarinus officinalis L., enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. Carnosol may as an agonist of TRPA1 with an EC50 value of 12.46 µM.
MSC2363318A, also known as M2698, is an orally available inhibitor of the serine/threonine protein kinases ribosomal protein S6 Kinase (p70S6K) and Akt (protein kinase B), with potential antineoplastic activity.
LJI308 is a potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
LY2584702 HCl is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir.
Tags: RSK | PI3K/Akt/mTOR | MAPK/ERK Pathway | RSK 相关产品
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