GSK840是一种选择性的 RIP3 激酶抑制剂，IC₅₀ 为 0.9 nM，能够抑制 RIP3 激酶活性，广泛用于凋亡及坏死调控机制的研究，尤其适用于与凋亡和坏死性炎症相关的疾病研究。

RIPK1-IN-7是一种强效的 RIPK1 抑制剂，具有抗炎和抗癌的潜力，用于相关疾病的研究中。

GSK583 is a selective inhibitor of RIP2 Kinase and IC50 value is 5 nM.

Necrostatin-1 is an inhibitor of RIP1 and can decrease TNF-α-induced necroptosis with EC50 of 490 nM.

NSC 146109 HCl是一种小分子 p53 激活剂，通过靶向 MDMX 激活 p53 通路，诱导乳腺癌细胞凋亡。该化合物为乳腺癌治疗的研究提供了新的思路和潜在治疗靶点。

Nec-34 can synergize with Nec-1s to inhibit RIPK1 in vitro and in vivo.

RIP2 kinase inhibitor 1 is a receptor interacting protein-2 (RIP2) kinase inhibitor.

RIPA-56 is a RIP1 inhibitor with EC50 value of 28nM. It efficiently reduced TNFα-induced mortality and multi-organ damage.

PK68是一种特异性RIPK1抑制剂，能够抑制RIPK1依赖性坏死，对TNF诱导的全身炎症反应综合征有显著的改善作用。

GSK2983559 free acid is a small-molecule inhibitor of RIP2 kinase. GSK2983559 free acid potently binds to RIP2 kinase with good kinase specificity and has excellent activity in blocking many proinflammatory cytokine responses in vivo .

HS1371 is an ATP-competitive and novel kinase inhibitor of RIP3-mediated necroptosis which can directly bind to RIP3.

GSK'547 is a highly selective and potent RIP1 inhibitor with improved oral bioavailability.

GSK-843是一种选择性 RIP3 (RIPK3) 抑制剂，IC₅₀ 为 8.6 nM，通过抑制 RIP3 激酶活性 (IC₅₀ = 6.5 nM) 展现出显著的抗炎活性，适用于炎症和凋亡相关机制的研究。

GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells.

GSK3145095 is a potent and orally active RIPK1 inhibitor with IC50 of 5 nM and potential antineoplastic and immunomodulatory activities.

GSK2982772 is an inhibitor of receptor interacting protein 1 (RIP1) with IC50 of 16 nM and it is used for the treatment of inflammatory diseases.

Resibufogenin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, displays great potential as a chemotherapeutic agent in oncology.

GSK'963 inhibits RIP1-dependent cell death with an IC50 of between 1 and 4 nM in human and murine cells.

ICCB-19 HCl是一种 TRADD 抑制剂，能够干扰 TRADD 的功能，具有研究免疫和炎症的潜力。

Necrostatin-5是一种高效的细胞坏死（Necroptosis）和 RIP1 激酶抑制剂，EC₅₀ 为 0.24 µM。该分子具有显著的心脏保护作用，广泛用于研究坏死性细胞死亡的调控机制。