货号:A734242 同义名: H 376/95;Exanta
Ximelagatran是一种口服活性凝血酶抑制剂,选择性和竞争性地抑制游离和凝块结合的凝血酶。该化合物具有抗凝血作用,药代动力学和药效学表现出可预测的剂量依赖性,适用于抗凝血治疗的研究。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | Thrombin ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dabigatran |
+++
Thrombin, IC50: 9.3 nM |
98% | |||||||||||||||||
Dabigatran etexilate | ✔ | 98% | |||||||||||||||||
Argatroban | 99%+ | ||||||||||||||||||
Heparin sodium salt | ✔ | ≥150 u/mg | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Ximelagatran is an orally active thrombin inhibitor that selectively and competitively inhibits free or clot-bound thrombin. Ximelagatran can be used as an anticoagulant with rapid onset of action, predictable, dose-dependent pharmacokinetic and pharmacodynamic properties[1][2].Ximelagatran is currently being used in the development of anticoagulants for the prevention and treatment of thromboembolism. Ximelagatran is rapidly absorbed and rapidly converted to its active form, Melagatran. Preliminary studies have demonstrated the efficacy and safety of Ximelagatran in the prevention of venous thromboembolism following total knee or total hip arthroplasty[3]. . |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.56mL 2.11mL 1.06mL |
21.12mL 4.22mL 2.11mL |
CAS号 | 192939-46-1 |
分子式 | C24H35N5O5 |
分子量 | 473.565 |
别名 | H 376/95;Exanta;Exarta;H 376-95 |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,Store in freezer, under -20°C |
溶解度 |
DMSO: 250 mg/mL(527.91 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |