Sorbic Acid inhibits growth of fungi, yeast, mold and some bacteria and is nearly nontoxic to humans. It's a natural preservative that comes from the rowan berries, Sorbus aucuparia (family Rosaceae) and widely used in foods, drugs, and cosmetic products as preservatives.
Sorbic acid (Sorbate ) generally is an effective inhibitor of most molds and yeasts and some bacteria. Environmental factors such as pH, water activity, temperature, atmosphere, microbial load, microbial flora and certain food components can influence the effectiveness of sorbate. Strains of microorganisms resistant to sorbate exist and therefore are common causes of food spoilage. Some molds and bacteria are able to degrade sorbate[1]. Sorbate and benzoate showed inhibitory activities against C. perfringens in the rich medium, no such effect was observed in cooked chicken meat[2]. Sorbate concentration decreased during film storage due to its oxidative degradation. Active films resulted more yellow and less transparent than films without sorbate. The minimum inhibitory concentration of sorbate resulted 0.3%, regardless of the starch type and the formulation pH[3].
United States, Minnesota
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University of Minnesota
Minneapolis, Minnesota, United States, 55455
United States, Washington
Kaiser Permanente Washington Health Research Institute
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United States, Michigan
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Henry Ford Hospital
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Detroit, Michigan, United States, 48202
Contact: Allen A Kadado, MD 248-990-0410 akadado1@hfhs.org 收起 <<
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UCLA Center for Prevention Research
Los Angeles, California, United States, 90024
United States, Pennsylvania
Magee/University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213 收起 <<
Congenital Heart Disease
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Brain Development
Cardiac Surgery
Neurodevelopmental Disability
Fetal Neuroprotection 收起 <<
Phase 2
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December 2021
United States, Pennsylvania
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The Children's Hospital of Philadelphia
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Philadelphia, Pennsylvania, United States, 19104
Contact: Nancy Burnham, MSN 215-410-0721 burnhamn@email.chop.edu 收起 <<
United States, New York
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University of Rochester Eastman Dental Center
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Rochester, New York, United States, 14620
Contact: Christine Lung, MS 585-275-5087 Christine_Lung@urmc.rochester.edu 收起 <<
United States, New York
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Albert Einstein College of Medicine
Bronx, New York, United States, 10451
United States, Utah
University of Utah
Salt Lake City, Utah, United States, 84112 收起 <<
South Africa
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Pietermaritzburg, Kwa-Zulu NAtal, South Africa, 316
Desmond Tutu HIV Centre / University of Cape Town
Cape Town, South Africa
Perinatal HIV Research Unit / University of the Witwatersrand
Diepkloof, South Africa
Wits Reproductive Health and HIV Institute / University of the Witwatersrand
Hillbrow, South Africa
Qhakaza Mbokodo Research Clinic
Ladysmith, South Africa, 3370
Medunsa Clinical Research Unit / Ga-Ra
Pretoria, South Africa
The Aurum Institute (Rustenburg)
Rustenburg, South Africa
Setshaba Research Centre
Soshanguve, South Africa
The Aurum Institute, Tembisa Hospital
Tembisa, South Africa 收起 <<
Antioxidant Role of the Lutein... 展开 >> in Preterm Newborn 收起 <<
Not Applicable
Recruiting
October 1, 2018
Italy
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Napoli, Italia, Italy, 80100
Contact: Giuseppe De Bernardo, M.D. +393357441303 pinodebtin@gmail.com
Contact: Desiree Sordino, M.D. +393383482584 dsordino@gmail.com
Principal Investigator: Giuseppe De Bernardo, M.D.
Azienda Ospedaliera Universitaria Padova
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Padova, Italia, Italy, 35128
Contact: Daniele Trevisanuto, Prof. +393406632734 daniele.trevisanuto@gmail.com
Sub-Investigator: Daniele Trevisanuto, Prof.
Azienda Ospedaliera Le Scotte Siena
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Siena, Italia, Italy, 53100
Contact: Giuseppe Buonocore, Prof. +393491770396 buonocore@unisi.it
Sub-Investigator: Giuseppe Buonocore, Prof.
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