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Masoprocol {[allProObj[0].p_purity_real_show]}

货号:A914482 同义名: meso-Nordihydroguaiaretic acid;meso-NDGA

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Masoprocol 化学结构 CAS号:27686-84-6
Masoprocol 化学结构
CAS号:27686-84-6
Masoprocol 3D分子结构
CAS号:27686-84-6
Masoprocol 化学结构 CAS号:27686-84-6
Masoprocol 3D分子结构 CAS号:27686-84-6
规格 价格 会员价 库存 数量
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Masoprocol 纯度/质量文件 产品仅供科研

货号:A914482 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

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产品名称 lipoxygenase 其他靶点 纯度
Zileuton 97%
Nordihydroguaiaretic acid 99%+
MK-886 99%+
Esculetin 98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Masoprocol 生物活性

描述 Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

Masoprocol 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00259818 Cancer Phase 1 Completed - United States, Arizona ... 展开 >> Premiere Oncology of Arizona Scottsdale, Arizona, United States United States, New York Albert Einstein College of Medicine Bronx, New York, United States United States, Tennessee Sarah Cannon Cancer Center Nashville, Tennessee, United States 收起 <<
NCT00664586 Refractory Solid Tumors ... 展开 >> Lymphoma 收起 << Phase 1 Terminated(Funding constraints... 展开 >>) 收起 << - United States, Tennessee ... 展开 >> The Sarah Cannon Cancer Center Nashville, Tennessee, United States, 37203 收起 <<
NCT00664677 Leukemias Acu... 展开 >>te Myeloid Leukemia (AML) Acute Lymphocytic Leukemia (ALL) Adult T Cell Leukemia (ATL) Chronic Myeloid Leukemia (CML-BP) Chronic Lymphocytic Leukemia (CLL) Myelodysplastic Syndrome (MDS) Chronic Myelomonocytic Leukemia (CMML) 收起 << Phase 1 Terminated(Funding constraints... 展开 >>) 收起 << - United States, North Carolina ... 展开 >> UNC, Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina, United States, 27599 收起 <<

Masoprocol 参考文献

[1]Gowri MS, Reaven GM, et al. Effect of masoprocol on glucose transport and lipolysis by isolated rat adipocytes. Metabolism. 1999 Apr;48(4):411-4.

[2]Reed MJ, Meszaros K, et al. Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes. Diabetologia. 1999 Jan;42(1):102-6.

Masoprocol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.31mL

0.66mL

0.33mL

16.54mL

3.31mL

1.65mL

33.07mL

6.61mL

3.31mL

Masoprocol 技术信息

CAS号27686-84-6
分子式C18H22O4
分子量 302.365
别名 meso-Nordihydroguaiaretic acid;meso-NDGA
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度

DMSO: 105 mg/mL(347.26 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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