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Maohuoside A {[allProObj[0].p_purity_real_show]}

货号:A673676

Maohuoside A, a natural product isolated and purified from the roots of Epimedium brevicornu Maxim, seems to enhance the osteogenesis of rMSC and bone marrow-derived mesenchymal stem cells at least partly via the BMP and MAPK signaling pathways and bone morphogenetic protein signalling, respectively.

Maohuoside A 化学结构 CAS号:128988-55-6
Maohuoside A 化学结构
CAS号:128988-55-6
Maohuoside A 3D分子结构
CAS号:128988-55-6
Maohuoside A 化学结构 CAS号:128988-55-6
Maohuoside A 3D分子结构 CAS号:128988-55-6
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Maohuoside A 纯度/质量文件 产品仅供科研

货号:A673676 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

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产品名称 ALK1 ALK2 ALK3 ALK4 ALK6 Smad3 TGF-β TGFβRI/ALK5 TGFβRII 其他靶点 纯度
LDN193189 ++++

ALK1, IC50: 0.8 nM

++++

ALK2, IC50: 0.8 nM

+++

ALK3, IC50: 5.3 nM

+++

ALK6, IC50: 16.7 nM

99%+
LDN-212854 ++++

ALK1, IC50: 2.4 nM

++++

ALK2, IC50: 1.3 nM

+

ALK3, IC50: 85.8 nM

+

ALK4, IC50: 2133 nM

+

ALK5, IC50: 9276 nM

99%+
ML347 ++

ALK1, IC50: 46 nM

++

ALK2, IC50: 32 nM

98%
K02288 ++++

ALK1, IC50: 1.8 nM

++++

ALK2, IC50: 1.1 nM

++

ALK3, IC50: 34.4 nM

+++

ALK6, IC50: 6.4 nM

99%+
LDN-193189 dihydrochloride ++++

ALK1, IC50: 0.8 nM

++++

ALK2, IC50: 0.8 nM

+++

ALK3, IC50: 5.3 nM

+++

ALK6, IC50: 16.7 nM

99%
LDN-214117 ++

ALK2, IC50: 24 nM

98%
DMH-1 +

ALK2, IC50: 107.9 nM

99%+
SB-505124 +

ALK4, IC50: 129 nM

++

ALK5, IC50: 47 nM

99%+
Vactosertib +++

ALK4, IC50: 13 nM

+++

ALK5, IC50: 11 nM

99%+
Alantolactone 98%
SIS3 97%
Pirfenidone 98%
Hesperetin 97%
RepSox ++++

TGFβR1(ALK5), IC50: 4 nM

98%
GW788388 +++

ALK5, IC50: 18 nM

98%
LY364947 ++

TGFβRI, IC50: 59 nM

+

TGFβRII, IC50: 0.4 μM

98%
SD-208 ++

TGF-βRI (ALK5), IC50: 48 nM

98%
SB-525334 +++

TGFβR1(ALK5), IC50: 14.3 nM

99%+
LY2109761 ++

TβRI, Ki: 38 nM

+

TβRII, Ki: 300 nM

99%+
Galunisertib ++

TβRI, IC50: 56 nM

98%
SB 431542 +

ALK5, IC50: 94 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Maohuoside A 生物活性

描述 Maohuoside A, a natural product isolated and purified from the roots of Epimedium brevicornu Maxim, seems to enhance the osteogenesis of rMSC and bone marrow-derived mesenchymal stem cells at least partly via the BMP and MAPK signaling pathways and bone morphogenetic protein signalling, respectively.

Maohuoside A 参考文献

[1]Cai M, Li G, et al. Maohuoside A acts in a BMP-dependent manner during osteogenesis. Phytother Res. 2013 Aug;27(8):1179-84.

[2]Yang L, Wang NL, Cai GP. Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways. Mol Cell Biochem. 2011 Dec;358(1-2):37-44.

Maohuoside A 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.82mL

0.36mL

0.18mL

9.12mL

1.82mL

0.91mL

18.23mL

3.65mL

1.82mL

Maohuoside A 技术信息

CAS号128988-55-6
分子式C27H32O12
分子量 548.536
别名
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,2-8°C

溶解度
动物实验配方
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